Výsledky vyhledávání - "Z-H. Lucy Zhou"

Regulation of monocyte chemoattractant protein (MCP)‐1 transcription by interferon‐gamma (IFN‐γ) in human astrocytoma cells: postinduction refractory state of the gene, governed by its upstream elements

Autor: Sarah Tyler, Tao Wei, M.R. Sandhya Rani, Yulong Han, Richard M. Ransohoff, Sümer Aras, Z.-H. Lucy Zhou, Priya Chaturvedi

Publikováno v: The FASEB Journal. 15:383-392

Monocyte chemoattractant protein (MCP)-1 is expressed by astrocytes in diverse inflammatory states and is a key regulator of monocyte recruitment to the central nervous system (CNS). In the current study, we addressed mechanisms by which transcriptio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa42e2cb6d032569cc513e714692ccf5
https://doi.org/10.1096/fj.00-0373com

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TGF?1 selectively up-regulates CCR1 expression in primary murine astrocytes

Autor: Z.-H. Lucy Zhou, Jintang Wang, Yulong Han, Richard M. Ransohoff

Publikováno v: Glia. 30:1-10

Chemokine receptors dictate the cellular responses to chemokines on target cells. Therefore, the regulation of expression of chemokine receptors is likely a crucial point for the regulation of chemokine action. Here we show that CC chemokine receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c88ddd39002990f42027856797499749
https://doi.org/10.1002/(sici)1098-1136(200003)30:1<1::aid-glia1>3.0.co

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TNF-α Suppresses IFN-γ-Induced MHC Class II Expression in HT1080 Cells by Destabilizing Class IItrans-Activator mRNA

Autor: Yulong Han, Z-H. Lucy Zhou, Richard M. Ransohoff

Publikováno v: The Journal of Immunology. 163:1435-1440

Precise regulation of MHC class II gene expression is crucial for development and function of the immune system. Class II trans-activator (CIITA) has been shown to be required for constitutive and IFN-γ-induced MHC class II transcription. TNF-α is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a83ebd99a3db7be57b0e989168abc6fb
https://doi.org/10.4049/jimmunol.163.3.1435

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IFN-γ Induction of the Human Monocyte Chemoattractant Protein (hMCP)-1 Gene in Astrocytoma Cells: Functional Interaction Between an IFN-γ-Activated Site and a GC-Rich Element

Autor: Z-H Lucy Zhou, Priya Chaturvedi, Yu-long Han, Sumer Aras, Yi-shuan Li, Pappachan E. Kolattukudy, Dongsheng Ping, Jeremy M. Boss, Richard M. Ransohoff

Publikováno v: The Journal of Immunology. 160:3908-3916

We characterized regulation of the human monocyte chemoattractant protein-1 (hMCP-1) gene by IFN-γ in astrocytoma cells, because astroglial cells express chemokines in several central nervous system inflammatory states. It was found that IFN-γ-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2893d7c2b63c0fd730bc502b5d32088
https://doi.org/10.4049/jimmunol.160.8.3908

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