Zobrazeno 1 - 10
of 2 329
pro vyhledávání: '"Z-DNA"'
Publikováno v:
Genomics & Informatics, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract The untranslated regions (UTRs) of genes significantly impact various biological processes, including transcription, posttranscriptional control, mRNA stability, localization, and translation efficiency. In functional areas of genomes, non-B
Externí odkaz:
https://doaj.org/article/0b829b77e77242d2bba5aa018fd1c237
Publikováno v:
Annals of Hepatology, Vol 29, Iss 4, Pp 101475- (2024)
Introduction and Objectives: Acute liver injury (ALI) is characterized by massive hepatocyte death with high mortality and poor prognosis. Hepatocyte pyroptosis plays a key role in the physiopathological processes of ALI, which can damage mitochondri
Externí odkaz:
https://doaj.org/article/de6e1f40815647b0816ba2a8e76fc237
Autor:
Du Hyeong Lee, Woo Hyeon Bae, Hongseok Ha, Woo Ryung Kim, Eun Gyung Park, Yun Ju Lee, Jung-min Kim, Hae Jin Shin, Heui-Soo Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Z-DNA, a well-known non-canonical form of DNA involved in gene regulation, is often found in gene promoters. Transposable elements (TEs), which make up 45% of the human genome, can move from one location to another within the genome. TEs pla
Externí odkaz:
https://doaj.org/article/5e16188efd294295bde17ed2c5a5016a
Autor:
Harp, Joel M.1, Coates, Leighton2, Sullivan, Brendan2, Egli, Martin1 martin.egli@vanderbilt.edu
Publikováno v:
Acta Crystallographica: Section F, Structural Biology Communications. Oct2018, Vol. 74 Issue 10, p603-609. 6p.
Autor:
Vongsutilers, Vorasit1,2 vorasit.v@chula.ac.th, Sawaspaiboontawee, Kulwadee1,2, Tuesuwan, Bodin1,2, Shinohara, Yoko3, Kawai, Gota3
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 2018, Vol. 37 Issue 9, p485-497. 13p.
Autor:
Alan Herbert
Alan Herbert has played a leading part in discovering the biological roles for a high-energy form of DNA twisted to the left rather than to the right. Both Z-DNA and the Z-RNA sensing proteins are critical for protecting hosts against both viruses an
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Autor:
Alan Herbert
Publikováno v:
Royal Society Open Science, Vol 11, Iss 6 (2024)
The Zα fold specifically binds to both Z-DNA and Z-RNA, left-handed nucleic acid structures that form under physiological conditions and are encoded by flipons. I trace the Zα fold back to unicellular organisms representing all three domains of lif
Externí odkaz:
https://doaj.org/article/1a103e69cdc745379a354e7616bfae4c
Autor:
Dajun Zhang, Yu Hao, Xing Yang, Xijuan Shi, Dengshuai Zhao, Lingling Chen, Huanan Liu, Zixiang Zhu, Haixue Zheng
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
African swine fever (ASF) is an infectious disease characterized by hemorrhagic fever, which is highly pathogenic and causes severe mortality in domestic pigs. It is caused by the African swine fever virus (ASFV). ASFV is a large DNA virus and primar
Externí odkaz:
https://doaj.org/article/397d08032dbd4b998684fc05265c272b
Publikováno v:
Virus Research, Vol 343, Iss , Pp 199342- (2024)
African swine fever virus is known to suppress type-I interferon (IFN) responses. The main objective of this study was to screen early-expressed viral genes for their ability to suppress IFN production. Out of 16 early genes examined, I73R exhibited
Externí odkaz:
https://doaj.org/article/6f927be3cb1e4ad8a87315d65203b349