Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Z Toossi"'
Autor:
K. A. Wilkinson, T. D. Martin, S. M. Reba, H. Aung, R. W. Redline, W. H. Boom, Z. Toossi, S. A. Fulton
Publikováno v:
Infection and Immunity. 68:6505-6508
Publikováno v:
The Journal of Immunology. 159:4109-4116
Blood monocytes from patients with active tuberculosis are activated in vivo, as evidenced by an increase in the stimulated release of proinflammatory cytokines, such as TNF-alpha, and the spontaneous expression of IL-2R. Further, monocytes from pati
Publikováno v:
The Journal of Immunology. 156:3461-3468
As the main immunocytes lining pulmonary alveoli, alveolar macrophages (AM) are critical to the maintenance of immune hemostasis of the lung. This study examined the capacity of AM obtained from healthy individuals in comparison with autologous blood
Publikováno v:
The Journal of Immunology. 154:465-473
The expression of TGF-beta, a molecule that affects both immune responsiveness and wound healing, was examined in blood monocytes and granulomatous lesions from patients with active pulmonary tuberculosis. The spontaneous release of TGF-beta was high
Publikováno v:
Molecular medicine (Cambridge, Mass.). 7(3)
BACKGROUND: Prolonged exposure of alveolar macrophages (AM) to components of tobacco smoke, including nicotine and aromatic hydrocarbons, may lead to alterations in activation of cellular signaling pathways. In this study, we compared the spontaneous
Autor:
Z, Toossi
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 48(6)
Infection with Mycobacterium tuberculosis (MTB) is accompanied by an intense local inflammatory response which may be critical to the pathogenesis of tuberculosis. Activation of components of the innate immune response, such as recruitment of polymor
Autor:
Z, Toossi
Publikováno v:
Cytokines, cellularmolecular therapy. 4(2)
Tuberculosis persists as a major infectious disease contributing to significant morbidity and mortality worldwide. Presently, antituberculous chemotherapy remains the mainstay of control of tuberculosis; however, it is associated with complexities in
Publikováno v:
The Southeast Asian journal of tropical medicine and public health. 28(4)
Tuberculosis patients with pulmonary (N = 95) or lymph node disease (N = 23) were assessed for Th1 responses (PPD skin test and lymphocyte blastogenic and interferon gamma) and Th2 responses (polyclonal and antigen specific IgE). Skin test responses
Publikováno v:
Journal of clinical immunology. 17(5)
The pathophysiologic basis for the exuberant intracellular growth of Mycobacterium avium complex (MAC) in AIDS patients is unclear but may relate to altered expression of modulatory cytokines. Interleukin (IL)-1, IL-6, and TNF-alpha expression by mon
Publikováno v:
Journal of clinicallaboratory immunology. 49(2)
In humans, tuberculosis is associated with suppression of T-cell responses to antigens of Mycobacterium tuberculosis. Recently, the macrophage product, transforming growth factor-beta (TGF-beta) has been implicated in suppression of T-cell proliferat