Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Z Qui"'
Publikováno v:
Value in Health. 25:S268
Publikováno v:
Journal of Analytical Toxicology. 38:456-461
In order to achieve chromatographic separation, urine samples shown to be initially positive for amphetamines and methamphetamines in US Department of Defense immunoassays are derivatized with R-(-)-α-methoxy-α-(trifluoromethyl)phenylacetyl chlorid
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 90:e31.3-e31
ObjectivesThe impact of Traumatic Brain Injury (TBI) on the synapse is poorly understood. We examined the impact of TBI on the distribution of two postsynaptic density proteins (PSD95 and SAP102) at single-synapse resolution.Subjects44 male transgeni
Autor:
Roslyn A Taylor, Harry Z. Qui, Marie-Clare St. Rose, Anthony T. Vella, Adam T. Hagymasi, Adam J. Adler, Suman Bandyopadhyay
Publikováno v:
Immunology and cell biology
T cell tolerance to tumor antigens represents a major hurdle in generating tumor immunity. Combined administration of agonistic monoclonal antibodies to the costimulatory receptors CD134 plus CD137 can program T cells responding to tolerogenic antige
Autor:
Adam T. Hagymasi, Marie-Clare St. Rose, Robert B. Clark, Adam J. Adler, Marianne A. Mihalyo, Harry Z. Qui, Suman Bandyopadhyay
Publikováno v:
The Journal of Immunology. 183:4975-4983
Cbl-b is an E3 ubiquitin ligase that limits Ag responsiveness in T cells by targeting TCR-inducible signaling molecules. Cbl-b deficiency thus renders T cells hyperresponsive to antigenic stimulation and predisposes individuals toward developing auto
Publikováno v:
Immunology Letters. 122:214-218
Epigenetic remodeling of genes encoding effector cytokines that permit accessibility to the transcriptional machinery is a central event in the differentiation of naive T cells into effectors that can attack pathogens and tumors. Covalent modificatio
Autor:
Marianne A. Mihalyo, Robert S. Mittler, Harry Z. Qui, Aaron M. Slaiby, Suman Bandyopadhyay, Adam J. Adler, Hector L. Aguila, Adam T. Hagymasi, Meixiao Long, Anthony T. Vella
Publikováno v:
The Journal of Immunology. 181:7728-7737
We compared how CD4 vs CD8 cells attain the capacity to express the effector cytokine IFN-γ under both immunogenic and tolerogenic conditions. Although the Ifng gene locus was epigenetically repressed in naive Ag-inexperienced CD4 cells, it had alre
Autor:
Aaron M. Slaiby, Marianne A. Mihalyo, Adam J. Adler, Harry Z. Qui, Leo Lefrançois, David J. Zammit, Adam T. Hagymasi
Publikováno v:
The Journal of Immunology. 179:1524-1531
Bone marrow-derived APC are critical for both priming effector/memory T cell responses to pathogens and inducing peripheral tolerance in self-reactive T cells. In particular, dendritic cells (DC) can acquire peripheral self-Ags under steady state con
Publikováno v:
Public Health. 119:1111-1115
Summary Background North America's first medically supervised safer injection facility (SIF) for illicit drug users was opened in Vancouver, Canada on 22 September 2003. We examined the prevalence and correlates of hepatitis C (HCV) infection among a
Autor:
Adam T. Hagymasi, Suman Bandyopadhyay, Steven L. Reiner, Marie-Clare St. Rose, Robert S. Mittler, Scott M. Gordon, Anthony T. Vella, Raghunath Ramanarasimhaiah, Harry Z. Qui, Adam J. Adler, Antoine Ménoret
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(7)
Cytotoxic CD4 Th1 cells are emerging as a therapeutically useful T cell lineage that can effectively target tumors, but until now the pathways that govern their differentiation have been poorly understood. We demonstrate that CD134 (OX40) costimulati