Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Z M, Zaïr"'
Publikováno v:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 26(6)
EAC in its early stages, when it can potentially be cured, is rarely symptomatic and is associated with high mortality rates because in part of late-stage diagnosis. Given that DNA repair is an important contributory factor of early-stage malignancy,
Publikováno v:
Diseases of the Esophagus. Aug2013, Vol. 26 Issue 6, p644-650. 7p. 2 Graphs.
Autor:
Siegfried Knasmüller, Michael Fenech
Concerns about the adverse health effects of chemicals and radiation present in the environment and at workplaces have created the need for better detection systems to assess their potential to cause DNA damage in humans and other organisms across ec
Autor:
Glynis Nicholls, Kuresh Youdim
Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. The first volume comprehensively reviewed current knowledge and techniques in the transporter sciences
Autor:
Russell S Thomas, Michael D Waters
Research over the past decade has demonstrated that TGx methods of various types can be used to discriminate modes of mutagenesis as a function of dose. TGx can quickly inform safety evaluation regarding potential mechanisms of conventional outcomes
Autor:
Helmut Greim, Richard Albertini
Genotoxic carcinogens can lead to DNA mutations with the potential to cause cancer. Typically, a series of mutation events are needed before malignancy occurs so a single, small exposure may not result in disease. Also, cells have an armoury of defen