Výsledky vyhledávání - "Z I Randhawa"

A study of intermediates involved in the folding pathway for recombinant human macrophage colony-stimulating factor (M-CSF): Evidence for two distinct folding pathways

Autor: Z. I. Randhawa, D. Wood, J. A. Wilkins, H. E. Witkowska, M. K. Warren, J. Cone

Publikováno v: Protein Science. 2:244-254

The folding pathway for a 150-amino acid recombinant form of the dimeric cytokine human macrophage colony-stimulating factor (M-CSF) has been studied. All 14 cysteine residues in the biologically active homodimer are involved in disulfide linkages. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dff245ead5ad7f3213455c71ef3aea6c
https://doi.org/10.1002/pro.5560020213

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Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock

Autor: W Newman, L D Beall, C W Carson, G G Hunder, N Graben, Z I Randhawa, T V Gopal, J Wiener-Kronish, M A Matthay

Publikováno v: The Journal of Immunology. 150:644-654

A quantitative sandwich ELISA for E-selectin in the fluid phase (soluble E-selectin, sEs) has been developed that is sensitive to 100 pg/ml. The assay shows no reactivity with either L- or P-selectins. We have used this to determine the fate of E-sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7ae3b0a7a2a798bf849a5c784dd5b60
https://doi.org/10.4049/jimmunol.150.2.644

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Utilization of an active serine 101—-cysteine mutant to demonstrate the proximity of the catalytic serine 101 and histidine 237 residues in thioesterase II

Autor: Stuart Smith, Z I Randhawa, H E Witkowska, J Naggert, Andrzej Witkowski

Publikováno v: Journal of Biological Chemistry. 267:18488-18492

Thioesterase II is a 29-kDa monomer which, in certain specialized tissues, acts as a chain terminator in fatty acid synthesis by hydrolyzing medium-chain fatty acids from the fatty acid synthase. As with serine proteases, hydrolysis appears to involv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54f6ddf2cf6524090584830b5d9c191b
https://doi.org/10.1016/s0021-9258(19)36988-1

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Cloning, sequencing, and characterization of Escherichia coli thioesterase II

Autor: Z I Randhawa, B N Green, L DeVeaux, John E. Cronan, H Cho, M L Narasimhan, Stuart Smith, J Naggert

Publikováno v: Journal of Biological Chemistry. 266:11044-11050

The gene (tesB) encoding Escherichia coli thioesterase II, a low-abundance enzyme of unknown physiological function which can hydrolyze a broad range of acyl-CoA thioesters, has been localized by transposon mutagenesis, cloned and sequenced. A two-ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19ff7384085a28cb85b36f6beec74d65
https://doi.org/10.1016/s0021-9258(18)99125-8

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Incorporation of norleucine at methionine positions in recombinant human macrophage colony stimulating factor (M-CSF, 4-153) expressed in Escherichia coli: structural analysis

Autor: J. Cone, K Yamanishi, J. A. Wilkins, Z. I. Randhawa, P Hughes, Y Masui, H. E. Witkowska, P Arthur, S Yasuda, C Kletke

Publikováno v: Biochemistry. 33(14)

Expression of the 17.5-kDa truncated form of human recombinant macrophage colony stimulating factor (rM-CSF, 4-153) in Escherichia coli is complicated by the replacement of methionine residues by norleucine. In order to detect and quantitate this mis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9ebcaf83b17d24a5942f3755d5fa46
https://pubmed.ncbi.nlm.nih.gov/8155653

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A study of intermediates involved in the folding pathway for recombinant human macrophage colony-stimulating factor (M-CSF): evidence for two distinct folding pathways

Autor: J A, Wilkins, J, Cone, Z I, Randhawa, D, Wood, M K, Warren, H E, Witkowska

Publikováno v: Protein science : a publication of the Protein Society. 2(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad1a1e6559c866b879d599387aa93855
https://pubmed.ncbi.nlm.nih.gov/8443602

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Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock

Autor: W, Newman, L D, Beall, C W, Carson, G G, Hunder, N, Graben, Z I, Randhawa, T V, Gopal, J, Wiener-Kronish, M A, Matthay

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 150(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1daac375dd57d10b44aae3cbe6e50d9e
https://pubmed.ncbi.nlm.nih.gov/7678280

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Utilization of an active serine 101----cysteine mutant to demonstrate the proximity of the catalytic serine 101 and histidine 237 residues in thioesterase II

Autor: A, Witkowski, J, Naggert, H E, Witkowska, Z I, Randhawa, S, Smith

Publikováno v: The Journal of biological chemistry. 267(26)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c65b2fe3a853b42ba9fcc1fa9d72041
https://pubmed.ncbi.nlm.nih.gov/1526985

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Cloning, sequencing, and characterization of Escherichia coli thioesterase II

Autor: J, Naggert, M L, Narasimhan, L, DeVeaux, H, Cho, Z I, Randhawa, J E, Cronan, B N, Green, S, Smith

Publikováno v: The Journal of biological chemistry. 266(17)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1b97cda9d63452bd240198dd0a2f8a6
https://pubmed.ncbi.nlm.nih.gov/1645722

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