Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Z Gordon, Jiang"'
Autor:
Melanie Zheng, Aaron Hakim, Chigoziri Konkwo, Aimee M. Deaton, Lucas D. Ward, Marina G. Silveira, David N. Assis, AnnMarie Liapakis, Ariel Jaffe, Z. Gordon Jiang, Michael P. Curry, Michelle Lai, Michael H. Cho, Daniel Dykas, Allen Bale, Pramod K. Mistry, Silvia Vilarinho
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104747- (2023)
Summary: Background: Whole-exome sequencing (WES) is an effective tool for diagnosis in patients who remain undiagnosed despite a comprehensive clinical work-up. While WES is being used increasingly in pediatrics and oncology, it remains underutilize
Externí odkaz:
https://doaj.org/article/180bc15093c540db85713ec4b61984c6
Autor:
Sebastian Niezen, Elliot B. Tapper, Hirsh Trivedi, Michelle Lai, Michael P. Curry, Kenneth J. Mukamal, Z. Gordon Jiang
Publikováno v:
Hepatology Communications, Vol 6, Iss 4, Pp 898-909 (2022)
Cirrhosis, a rising cause of death in the United States, has an extended preclinical phase characterized by progressive liver fibrosis. Despite the developments in noninvasive fibrosis measurement, there is no recommended screening, in part due to an
Externí odkaz:
https://doaj.org/article/5f680f96783945c6974e4c8c2c105a0e
Autor:
Aaron Hakim, Matthew Moll, Dandi Qiao, Jiangyuan Liu, Jessica A. Lasky‐Su, Edwin K. Silverman, Silvia Vilarinho, Z. Gordon Jiang, Brian D. Hobbs, Michael H. Cho
Publikováno v:
Hepatology Communications, Vol 5, Iss 8, Pp 1348-1361 (2021)
The serpin family A member 1 (SERPINA1) Z allele is present in approximately one in 25 individuals of European ancestry. Z allele homozygosity (Pi*ZZ) is the most common cause of alpha 1‐antitrypsin deficiency and is a proven risk factor for cirrho
Externí odkaz:
https://doaj.org/article/12ecadbc09b84d74be1f2c5fa3d2dfa5
Autor:
Fredrik Åberg, Christopher J. Danford, Maja Thiele, Mats Talbäck, Ditlev Nytoft Rasmussen, Z. Gordon Jiang, Niklas Hammar, Patrik Nasr, Mattias Ekstedt, Anna But, Pauli Puukka, Aleksander Krag, Jouko Sundvall, Iris Erlund, Veikko Salomaa, Per Stål, Stergios Kechagias, Rolf Hultcrantz, Michelle Lai, Nezam Afdhal, Antti Jula, Satu Männistö, Annamari Lundqvist, Markus Perola, Martti Färkkilä, Hannes Hagström
Publikováno v:
Hepatology Communications, Vol 5, Iss 6, Pp 1021-1035 (2021)
The aspartate‐to‐alanine aminotransferase ratio (AAR) is associated with liver fibrosis, but its predictive performance is suboptimal. We hypothesized that the association between AAR and liver disease depends on absolute transaminase levels and
Externí odkaz:
https://doaj.org/article/cbe82f37a35346fa89a804d5505c178a
Autor:
Giuseppe Ietto, Valentina Iori, Mattia Gritti, Davide Inversini, Angelita Costantino, Sofia Izunza Barba, Z. Gordon Jiang, Giulio Carcano, Daniela Dalla Gasperina, Giuseppe Pettinato
Publikováno v:
Cells, Vol 12, Iss 10, p 1429 (2023)
Over 40,000 patients in the United States are estimated to suffer from end-stage liver disease and acute hepatic failure, for which liver transplantation is the only available therapy. Human primary hepatocytes (HPH) have not been employed as a thera
Externí odkaz:
https://doaj.org/article/92c09068975f446ca76cc83c6eb4d85c
Autor:
Ghideon Ezaz, Hirsh D. Trivedi, Margery A. Connelly, Claudia Filozof, Kellie Howard, Mark L.Parrish, Misung Kim, Mark A. Herman, Imad Nasser, Nezam H. Afdhal, Z. Gordon Jiang, Michelle Lai
Publikováno v:
Hepatology Communications, Vol 4, Iss 5, Pp 670-680 (2020)
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous disease driven by genetic and environmental factors. MicroRNAs (miRNAs) serve as pleiotropic post‐transcriptional regulators of cellular pathways. Although several miRNAs have been associa
Externí odkaz:
https://doaj.org/article/3e31e44a9bf34567b3f367787a2d4008
Autor:
Bynvant Sandhu, Maria C. Perez Matos, Stephanie Tran, Alexander Zhong, Eva Csizmadia, Misung Kim, Mark A. Herman, Imad Nasser, Michelle Lai, Z. Gordon Jiang
Publikováno v:
JHEP Reports, Vol 1, Iss 3, Pp 199-202 (2019)
Background & Aims: The I148M variant (rs738409) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) is by far the most important genetic determinant of non-alcoholic fatty liver disease (NAFLD). However, in the context of NAFLD, the tr
Externí odkaz:
https://doaj.org/article/d104e3d15577434a888733c1c309463a
Autor:
Christopher J. Danford, Margery A. Connelly, Irina Shalaurova, Misung Kim, Mark A. Herman, Imad Nasser, James D. Otvos, Nezam H. Afdhal, Z. Gordon Jiang, Michelle Lai
Publikováno v:
Hepatology Communications, Vol 2, Iss 12, Pp 1467-1478 (2018)
Nonalcoholic fatty liver disease (NAFLD) is a complex disease dictated by both genetic and environmental factors. While insulin resistance (IR) is a key pathogenic driver, two common genetic variants in patatin‐like phospholipase domain containing
Externí odkaz:
https://doaj.org/article/67bd652349954a62aa0fb703e5769fbd
Autor:
Z. Gordon Jiang, Elliot B. Tapper
Publikováno v:
Hepatology Communications, Vol 3, Iss 10, Pp 1293-1295 (2019)
Externí odkaz:
https://doaj.org/article/7d1f7e76adc94672a025d31f34d859ab
Autor:
Jiunn Song, Z. Gordon Jiang
Publikováno v:
Hepatology Communications. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a85c4d2a57130da549ce02a43a2e3abf
https://doi.org/10.1097/hc9.0000000000000124
https://doi.org/10.1097/hc9.0000000000000124