Výsledky vyhledávání - "Z Elaine Dowdy"

Akademický článek

High heritability of metabolomic profiles in families burdened with premature cardiovascular disease

Autor: Svati H Shah, Elizabeth R Hauser, James R Bain, Michael J Muehlbauer, Carol Haynes, Robert D Stevens, Brett R Wenner, Z Elaine Dowdy, Christopher B Granger, Geoffrey S Ginsburg, Christopher B Newgard, William E Kraus

Publikováno v: Molecular Systems Biology, Vol 5, Iss 1, Pp 1-7 (2009)

Abstract Integration of genetic and metabolic profiling holds promise for providing insight into human disease. Coronary artery disease (CAD) is strongly heritable, but the heritability of metabolomic profiles has not been evaluated in humans. We per

Externí odkaz: https://doaj.org/article/33b76d0f84194249ae833a7b95ee37d9

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Akademický článek

Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients

Autor: Jaime E. Mirowsky, Martha Sue Carraway, Radhika Dhingra, Haiyan Tong, Lucas Neas, David Diaz-Sanchez, Wayne Cascio, Martin Case, James Crooks, Elizabeth R. Hauser, Z. Elaine Dowdy, William E. Kraus, Robert B. Devlin

Publikováno v: Environmental Health, Vol 16, Iss 1, Pp 1-10 (2017)

Abstract Background Air pollution is a major risk factor for cardiovascular disease, of which ozone is a major contributor. Several studies have found associations between ozone and cardiovascular morbidity, but the results have been inconclusive. We

Externí odkaz: https://doaj.org/article/23f8027f84bf48b78af564a3620eec73

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Exposures to low-levels of fine particulate matter are associated with acute changes in heart rate variability, cardiac repolarization, and circulating blood lipids in coronary artery disease patients

Autor: Jaime E. Mirowsky, Martha Sue Carraway, Radhika Dhingra, Haiyan Tong, Lucas Neas, David Diaz-Sanchez, Wayne E. Cascio, Martin Case, James L. Crooks, Elizabeth R. Hauser, Z. Elaine Dowdy, William E. Kraus, Robert B. Devlin

Publikováno v: Environmental Research. 214:113768

Exposure to air pollution is a major risk factor for cardiovascular disease, disease risk factors, and mortality. Specifically, particulate matter (PM), and to some extent ozone, are contributors to these effects. In addition, exposures to these poll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e14b0a643db0e104163fe0bfaf3ead
https://doi.org/10.1016/j.envres.2022.113768

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High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort

Autor: Robert W. McGarrah, William E. Kraus, Damian M. Craig, Z. Elaine Dowdy, Svati H. Shah, Carol Haynes

Publikováno v: Atherosclerosis. 246:229-235

Background and Aims Recent failures of HDL cholesterol (HDL-C)-raising therapies to prevent cardiovascular disease (CVD) events have tempered the interest in the role of HDL-C in clinical risk assessment. Emerging data suggest that the atheroprotecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22553a3267167e73ae6f4dd8063650ea
https://doi.org/10.1016/j.atherosclerosis.2016.01.012

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A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience

Autor: Carol Haynes, Z. Elaine Dowdy, Svati H. Shah, Melissa Hurdle, L. Kristin Newby, Mark P. Donahue, Elizabeth R. Hauser, William E. Kraus, Geoffrey S. Ginsburg, Michael H. Sketch, Christopher B. Granger

Publikováno v: Journal of Cardiovascular Translational Research. 8:449-457

The CATHeterization GENetics (CATHGEN) biorepository was assembled in four phases. First, project start-up began in 2000. Second, between 2001 and 2010, we collected clinical data and biological samples from 9334 individuals undergoing cardiac cathet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8788899823f47d7f855209a95388577
https://doi.org/10.1007/s12265-015-9648-y

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A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic

Autor: David Diaz-Sanchez, Cavin K. Ward-Caviness, Karen LaRocque-Abramson, Svati H. Shah, Elizabeth R. Hauser, Z. Elaine Dowdy, Simon G. Gregory, Robert B. Devlin, Colette Blach, Elizabeth Grass, Wayne E. Cascio, William E. Kraus, Marie Lynn Miranda, Carol Haynes, Lucas M. Neas

Publikováno v: PLoS ONE
PLoS ONE 12:e0173880 (2017)
PLoS ONE, Vol 12, Iss 3, p e0173880 (2017)

Air pollution is a worldwide contributor to cardiovascular disease mortality and morbidity. Traffic-related air pollution is a widespread environmental exposure and is associated with multiple cardiovascular outcomes such as coronary atherosclerosis,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524db7d344414e9121fced4eb0faf19b
http://europepmc.org/articles/PMC5371323

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Additional file 2: Table S2. of Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients

Autor: Mirowsky, Jaime, Carraway, Martha, Dhingra, Radhika, Haiyan Tong, Neas, Lucas, Diaz-Sanchez, David, Cascio, Wayne, Case, Martin, Crooks, James, Hauser, Elizabeth, Z. Elaine Dowdy, Kraus, William, Devlin, Robert

Percent changes of measured factors with ambient ozone and PM2.5 concentrations using a two-pollutant model. Effect estimates (95% CI) were log-transformed, correspond to changes per IQR of the corresponding pollutants, and were adjusted for season,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7518af374c4744a2120908125640b5d3

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Additional file 1: Table S1. of Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients

Percent changes of measured factors with ambient ozone concentrations. Effect estimates (95% CI) were log-transformed, correspond to changes per IQR of ozone, and were adjusted for season, temperature, and humidity. Effect estimates for SumPSD, LF:HF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49db606c34511be60ffb6b467dabb377

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GLYCA, A NOVEL BIOMARKER OF SYSTEMIC INFLAMMATION, IMPROVES CARDIOVASCULAR RISK PREDICTION IN A HIGH-RISK CORONARY CATHETERIZATION COHORT

Autor: Robert W. McGarrah, Damian M. Craig, Carol Haynes, William E. Kraus, Z. Elaine Dowdy, Svati H. Shah

Publikováno v: Journal of the American College of Cardiology. 65(10)

Inflammatory biomarkers appear to characterize residual cardiovascular (CV) risk on top of traditional risk factors. GlycA is a serum measurement of enzymatically glycosylated acute phase proteins. GlycA correlates with existing inflammatory biomarke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9fdc6926dc5fcd1ec56e1cd2dbede1

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