Synthesis of pyrazolo-1,2,4-triazolo[4,3-a]quinoxalines as antimicrobial agents with potential inhibition of DHPS enzyme.

Autor: Z El-Attar MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt., Elbayaa RY; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy & Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt., Shaaban OG; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy & Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt., Habib NS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt., Abdel Wahab AE; Genetic Engineering & Biotechnology Research Institute (GEBRI), the City for Scientific Research & Technology Application, Borg El-Arab, Alexandria, Egypt., Abdelwahab IA; Department of Microbiology & Immunology, Faculty of Pharmacy& Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt., M El-Hawash SA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.

Publikováno v: Future medicinal chemistry [Future Med Chem] 2018 Sep 01; Vol. 10 (18), pp. 2155-2175. Date of Electronic Publication: 2018 Aug 08.