Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC.

Autor: Ellenbroek BD; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Kahler JP; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Arella D; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Lin C; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Jespers W; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Züger EA; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Drukker M; Leiden University, LACDR, NETHERLANDS, KINGDOM OF THE., Pomplun SJ; Leiden University, LACDR, Wassenaarseweg 76, 2333AL, Leiden, NETHERLANDS, KINGDOM OF THE.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Sep 24, pp. e202416082. Date of Electronic Publication: 2024 Sep 24.