IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion.

Autor: Herhaus L; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Electronic address: lina.herhaus@gmail.com., Gestal-Mato U; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Eapen VV; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Institutes of Medicine, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA., Mačinković I; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Institute of Biochemistry I, Goethe University School of Medicine, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Bailey HJ; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Riedberg Campus, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany., Prieto-Garcia C; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Misra M; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Riedberg Campus, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany., Jacomin AC; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Ammanath AV; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Bagarić I; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Michaelis J; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Vollrath J; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Riedberg Campus, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany; Max Planck Institute of Biophysics, Goethe University Frankfurt, Riedberg Campus, 60438 Frankfurt am Main, Germany., Bhaskara RM; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Riedberg Campus, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany., Bündgen G; Institute for Immunology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Covarrubias-Pinto A; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Husnjak K; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Zöller J; Max Planck Institute of Biophysics, Goethe University Frankfurt, Riedberg Campus, 60438 Frankfurt am Main, Germany., Gikandi A; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Institutes of Medicine, 450 Brookline Avenue, Boston, MA 02215, USA., Ribičić S; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Bopp T; Institute for Immunology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., van der Heden van Noort GJ; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands., Langer JD; Max Planck Institute of Biophysics, Goethe University Frankfurt, Riedberg Campus, 60438 Frankfurt am Main, Germany., Weigert A; Institute of Biochemistry I, Goethe University School of Medicine, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany., Harper JW; Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA., Mancias JD; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Institutes of Medicine, 450 Brookline Avenue, Boston, MA 02215, USA., Dikic I; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Riedberg Campus, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany; Max Planck Institute of Biophysics, Goethe University Frankfurt, Riedberg Campus, 60438 Frankfurt am Main, Germany. Electronic address: dikic@biochem2.uni-frankfurt.de.

Publikováno v: Cell [Cell] 2024 Dec 12; Vol. 187 (25), pp. 7285-7302.e29. Date of Electronic Publication: 2024 Oct 30.

Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA.

Autor: Kuhn BT; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt am Main, Germany.; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., Zöller J; Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany., Zimmermann I; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Gemeinhardt T; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt am Main, Germany., Özkul DH; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt am Main, Germany., Langer JD; Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Proteomics, Max Planck Institute for Brain Research, Frankfurt am Main, Germany., Seeger MA; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Geertsma ER; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt am Main, Germany. geertsma@mpi-cbg.de.; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. geertsma@mpi-cbg.de.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 30; Vol. 15 (1), pp. 7518. Date of Electronic Publication: 2024 Aug 30.

Magnesium Transporter MgtA revealed as a Dimeric P-type ATPase.

Autor: Zeinert R; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA., Zhou F; Unit on Structural Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA., Franco P; Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany., Zöller J; Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany., Lessen HJ; Unit on Membrane Chemical Physics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA., Aravind L; National Center for Biotechnology Information, National Institutes of Health, Bethesda MD 20892, USA., Langer JD; Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany., Sodt AJ; Unit on Membrane Chemical Physics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA., Storz G; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA., Matthies D; Unit on Structural Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 29. Date of Electronic Publication: 2024 Feb 29.

Ligand binding and conformational dynamics of the E. coli nicotinamide nucleotide transhydrogenase revealed by hydrogen/deuterium exchange mass spectrometry.

Autor: Zöller J; Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Proteomics, Max Planck Institute for Brain Research, Frankfurt am Main, Germany., Hong S; Department of Biochemistry, University of Illinois, Urbana, USA., Eisinger ML; Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Present address: AIMS, AbbVie Deutschland, GmbH & Co. KG., Ludwigshafen, Germany., Anderson M; Waters Corporation, Stamford Avenue, Altrincham Road, Wilmslow SK9 4AX, United Kingdom., Radloff M; Molecular Membrane Biology, Max Planck Institute of Biophysics, Frankfurt am Main, Germany., Desch K; Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Proteomics, Max Planck Institute for Brain Research, Frankfurt am Main, Germany., Gennis R; Department of Biochemistry, University of Illinois, Urbana, USA., Langer JD; Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Proteomics, Max Planck Institute for Brain Research, Frankfurt am Main, Germany.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2022 Sep 26; Vol. 20, pp. 5430-5439. Date of Electronic Publication: 2022 Sep 26 (Print Publication: 2022).

Does one size fit all? A qualitative study about the need for individualized information transfer for orthognathic patients.

Autor: Graf I; Department of Orthodontics, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Kerpener Str. 32, 50931, Cologne, Germany. isabelle.graf@uk-koeln.de., Enders A; Department for Research and Quality Management, Federal Centre for Health Education (BZgA), Cologne, Germany., Karbach U; Institute of Medical Sociology, Health Services Research and Rehabilitation Science, Faculties of Medicine and Human Sciences, University of Cologne, Cologne, Germany., Mihailovic T; Department of Orthodontics, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Kerpener Str. 32, 50931, Cologne, Germany., Kruse T; Department of Orthodontics, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Kerpener Str. 32, 50931, Cologne, Germany., Pollklas M; Clinical Psychology and Psychotherapy, University of Cologne, Cologne, Germany., Höfer K; Department of Operative Dentistry and Periodontology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany., Zöller J; Department of Dental Surgery and Oral, Maxillofacial and Plastic Facial Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany., Braumann B; Department of Orthodontics, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Kerpener Str. 32, 50931, Cologne, Germany.

Publikováno v: Head & face medicine [Head Face Med] 2022 Jun 30; Vol. 18 (1), pp. 22. Date of Electronic Publication: 2022 Jun 30.