Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Zöhre Ucurum"'
Autor:
Patrick Roth, Jean-Marc Jeckelmann, Inken Fender, Zöhre Ucurum, Thomas Lemmin, Dimitrios Fotiadis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Glucose is the primary source of energy for many organisms and is efficiently taken up by bacteria through a dedicated transport system that exhibits high specificity. In Escherichia coli, the glucose-specific transporter IICBGlc serves as t
Externí odkaz:
https://doaj.org/article/1bb3e7ddac5643729ffc8194c467b3ca
Autor:
Stephan Hirschi, Thomas Lemmin, Nooraldeen Ayoub, David Kalbermatter, Daniele Pellegata, Zöhre Ucurum, Jürg Gertsch, Dimitrios Fotiadis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Microbial ion-pumping rhodopsins (MRs) are extensively studied retinal-binding membrane proteins. However, their biogenesis, including oligomerisation and retinal incorporation, remains poorly understood. The bacterial green-light absorbing
Externí odkaz:
https://doaj.org/article/a108a1ee9b9d4375998fcce708237c39
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract Controlling the pH at the microliter scale can be useful for applications in research, medicine, and industry, and therefore represents a valuable application for synthetic biology and microfluidics. The presented vesicular system translates
Externí odkaz:
https://doaj.org/article/35689160b8d74aaf9cf18dec9f56eaa5
Autor:
Mirko Stauffer, Jean-Marc Jeckelmann, Hüseyin Ilgü, Zöhre Ucurum, Rajendra Boggavarapu, Dimitrios Fotiadis
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-10 (2022)
Understanding the molecular interactions between proton-dependent oligopeptide transporters and their inhibitors is key to drug and tool development, but high-resolution co-crystal structure data remains scarce. Here, the authors report the crystal s
Externí odkaz:
https://doaj.org/article/66a453ed865a4feeb9e84f5e9c5adfae
Autor:
Hüseyin Ilgü, Jean-Marc Jeckelmann, David Kalbermatter, Zöhre Ucurum, Thomas Lemmin, Dimitrios Fotiadis
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background The L-arginine/agmatine transporter AdiC is part of the arginine-dependent extreme acid resistance system of the bacterium Escherichia coli and its pathogenic varieties such as strain E. coli O157:H7. At the present time, there is
Externí odkaz:
https://doaj.org/article/5a4b8474e2574d198278bd45bb5855ef
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Novel approaches in synthetic biology focus on the bottom-up modular assembly of natural, modified natural or artificial components into molecular systems with functionalities not found in nature. A possible application for such techniques i
Externí odkaz:
https://doaj.org/article/cede18987b644fab93c3442631ccfd2c
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The cryo-EM structure of pentameric green-light absorbing proteorhodopsin together with molecular dynamics simulations and functional studies provides insights into the proton translocation pathway and oligomerization, and a protonation-dependent mec
Externí odkaz:
https://doaj.org/article/be15953b5e8e49b3be8f4c74426e812d
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100024- (2020)
The green-light absorbing proteorhodopsin (GPR) is the prototype of bacterial light-driven proton pumps. It has been the focus of continuous research since its discovery 20 years ago and has sparked the development and application of various biophysi
Externí odkaz:
https://doaj.org/article/e14727547c1940b9b8b38396b4e0fe83
Autor:
Satish Kantipudi, Jean-Marc Jeckelmann, Zöhre Ucurum, Patrick D. Bosshart, Dimitrios Fotiadis
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7573 (2020)
The human L-type amino acid transporters LAT1 and LAT2 mediate the transport of amino acids and amino acid derivatives across plasma membranes in a sodium-independent, obligatory antiport mode. In mammalian cells, LAT1 and LAT2 associate with the typ
Externí odkaz:
https://doaj.org/article/050930156fa54866a99c41afe105fae7
Autor:
Mirko Stauffer, Stephan Hirschi, Zöhre Ucurum, Daniel Harder, Ramona Schlesinger, Dimitrios Fotiadis
Publikováno v:
Methods and Protocols, Vol 3, Iss 3, p 51 (2020)
The light-driven proton pump bacteriorhodopsin (BR) from the extreme halophilic archaeon Halobacterium salinarum is a retinal-binding protein, which forms highly ordered and thermally stable 2D crystals in native membranes (termed purple membranes).
Externí odkaz:
https://doaj.org/article/d7f1aa4c173a49d19ae0fb20b0a831ca