Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Zélia Gouveia"'
1
Renal control of disease tolerance to malaria
Autor: Viktória Jeney, Miguel P. Soares, Susana Ramos, Claudia Bank, Ana Ribeiro, Birte Blankenhaus, Raffaella Gozzelino, Temitope W. Ademolue, Faouzi Braza, Subhashini Bolisetty, Zélia Gouveia, Anupam Agarwal, Laura del Barrio, Damian L. Trujillo, Erida Gjini, Pedro Faísca, Abolfazl Zarjou, Silvia Cardoso, Balamurugan Sundaram, Ana Rita Carlos, Sofia Rebelo, Rui Martins
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Significance Malaria, the disease caused by Plasmodium spp. infection, remains a major global cause of morbidity and mortality, claiming the lives of over ∼4.5 × 105 individuals per year. Paradoxically, however, up to 98% of infected individuals s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b99e81101a1adec37eaf0cf0ced02c
https://doi.org/10.1073/pnas.1822024116
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2
Labile heme impairs hepatic microcirculation and promotes hepatic injury
Autor: Kerstin Galler, Zélia Gouveia, Raphael A. Seidel, Ute Neugebauer, Georg Pohnert, Stefan H. Heinemann, Mark G. Clemens, Franziska A. Englert, Sebastian Weis, Christoph Sponholz, Michael Bauer, Miguel P. Soares
Publikováno v: Archives of Biochemistry and Biophysics
Sepsis is a life-threatening clinical syndrome defined as a deregulated host response to infection associated with organ dysfunction. Mechanisms underlying the pathophysiology of septic liver dysfunction are incompletely understood. Among others, the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d087b0f9851e6ca498b251b509dd8a3c
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4
Characterization of plasma labile heme in hemolytic conditions
Autor: Zélia Gouveia, Ana Catarina Cunha Santos, Ana Rita Carlos, Susana Ramos, Roland Stocker, Frederico Aires-da-Silva, Sónia S. Leal, João Gonçalves, Olga Iranzo, Miguel P. Soares, Xiaojing Yuan, Cláudio M. Gomes, Smilja Todorovic, Iqbal Hamza, Ghassan J. Maghzal
Publikováno v: FEBS Journal
FEBS Journal, 2017, 284 (19), pp.3278-3301. ⟨10.1111/febs.14192⟩
The FEBS journal
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
FEBS Journal, Wiley, 2017, 284 (19), pp.3278-3301. ⟨10.1111/febs.14192⟩
The deposited article is the accepted manuscript (post-print version) posted online 7 August 2017 and provided by The Febs Journal. This article has been accepted for publication and undergone full peer review but has not been through the copyediting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec98edeaf032d8a197cc09b5091c007
https://hal.science/hal-01793489
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5
Akademický článek
Identification of Small Molecules Affecting the Secretion of Therapeutic Antibodies with the Retention Using Selective Hook (RUSH) System
Autor: Mathilde Coulet, Sylvie Lachkar, Marion Leduc, Marc Trombe, Zelia Gouveia, Franck Perez, Oliver Kepp, Guido Kroemer, Stéphane Basmaciogullari
Publikováno v: Cells, Vol 12, Iss 12, p 1642 (2023)
Unlocking cell secretion capacity is of paramount interest for the pharmaceutical industry focused on biologics. Here, we leveraged retention using a selective hook (RUSH) system for the identification of human osteosarcoma U2OS cell secretion modula
Externí odkaz: https://doaj.org/article/4e8d2b8b7b4849619780f26877bc9c09
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6
Heme Cytotoxicity and the Pathogenesis of Immune-Mediated Inflammatory Diseases
Autor: Rasmus Larsen, Miguel P. Soares, Zélia Gouveia, Raffaella Gozzelino
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Pharmacology, Vol 3 (2012)
Frontiers in Pharmacology
Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of hemoproteins essential to support life under aerobic conditions. The Fe contained within the prosthetic heme groups of these hemoproteins can catalyze the production of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c246743286d57623998ea052a4b9d4f
https://doi.org/10.3389/fphar.2012.00077
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7
Probing the chemotaxis periplasmic sensor domains from Geobacter sulfurreducens by combined resonance Raman and molecular dynamic approaches: NO and CO sensing
Autor: Miguel Pessanha, Ariel G. De Candia, Smilja Todorovic, Ana P. Fernandes, Marcelo A. Marti, Zélia Gouveia, Carlos A. Salgueiro, Teresa Catarino, Daniel H. Murgida, P. Raj Pokkuluri
Publikováno v: The journal of physical chemistry. B. 114(34)
The periplasmic sensor domains encoded by genes gsu0582 and gsu0935 are part of methyl accepting chemotaxis proteins in the bacterium Geobacter sulfurreducens (Gs). The sensor domains of these proteins contain a heme-c prosthetic group and a PAS-like
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1739db17cf7aa815851fde7ab62fe71a
https://pubmed.ncbi.nlm.nih.gov/20690670
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8
The alternative oxidase family of Vitis vinifera reveals an attractive model to study the importance of genomic design
Autor: Zélia Gouveia, Birgit Arnholdt-Schmitt, Augusto Peixe, Hélia Cardoso, José Hélio Costa, Dirce Fernandes de Melo
Publikováno v: Physiologia plantarum. 137(4)
'Genomic design' refers to the structural organization of gene sequences. Recently, the role of intron sequences for gene regulation is being better understood. Further, introns possess high rates of polymorphism that are considered as the major sour
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e7db1c23750cdb8a91dbcbf2ff0eeb
https://pubmed.ncbi.nlm.nih.gov/19682279
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