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Akademický článek

Software tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values

Autor: Jeremy P. Koelmel, Jason A. Cochran, Candice Z. Ulmer, Allison J. Levy, Rainey E. Patterson, Berkley C. Olsen, Richard A. Yost, John A. Bowden, Timothy J. Garrett

Publikováno v: BMC Bioinformatics, Vol 20, Iss 1, Pp 1-13 (2019)

Abstract Background Lipidomics, the comprehensive measurement of lipids within a biological system or substrate, is an emerging field with significant potential for improving clinical diagnosis and our understanding of health and disease. While lipid

Externí odkaz: https://doaj.org/article/12f50269baf64f3d8c2932396d7b0de3

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Akademický článek

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma[S]

Autor: John A. Bowden, Alan Heckert, Candice Z. Ulmer, Christina M. Jones, Jeremy P. Koelmel, Laila Abdullah, Linda Ahonen, Yazen Alnouti, Aaron M. Armando, John M. Asara, Takeshi Bamba, John R. Barr, Jonas Bergquist, Christoph H. Borchers, Joost Brandsma, Susanne B. Breitkopf, Tomas Cajka, Amaury Cazenave-Gassiot, Antonio Checa, Michelle A. Cinel, Romain A. Colas, Serge Cremers, Edward A. Dennis, James E. Evans, Alexander Fauland, Oliver Fiehn, Michael S. Gardner, Timothy J. Garrett, Katherine H. Gotlinger, Jun Han, Yingying Huang, Aveline Huipeng Neo, Tuulia Hyötyläinen, Yoshihiro Izumi, Hongfeng Jiang, Houli Jiang, Jiang Jiang, Maureen Kachman, Reiko Kiyonami, Kristaps Klavins, Christian Klose, Harald C. Köfeler, Johan Kolmert, Therese Koal, Grielof Koster, Zsuzsanna Kuklenyik, Irwin J. Kurland, Michael Leadley, Karen Lin, Krishna Rao Maddipati, Danielle McDougall, Peter J. Meikle, Natalie A. Mellett, Cian Monnin, M. Arthur Moseley, Renu Nandakumar, Matej Oresic, Rainey Patterson, David Peake, Jason S. Pierce, Martin Post, Anthony D. Postle, Rebecca Pugh, Yunping Qiu, Oswald Quehenberger, Parsram Ramrup, Jon Rees, Barbara Rembiesa, Denis Reynaud, Mary R. Roth, Susanne Sales, Kai Schuhmann, Michal Laniado Schwartzman, Charles N. Serhan, Andrej Shevchenko, Stephen E. Somerville, Lisa St. John-Williams, Michal A. Surma, Hiroaki Takeda, Rhishikesh Thakare, J. Will Thompson, Federico Torta, Alexander Triebl, Martin Trötzmüller, S. J. Kumari Ubhayasekera, Dajana Vuckovic, Jacquelyn M. Weir, Ruth Welti, Markus R. Wenk, Craig E. Wheelock, Libin Yao, Min Yuan, Xueqing Heather Zhao, Senlin Zhou

Publikováno v: Journal of Lipid Research, Vol 58, Iss 12, Pp 2275-2288 (2017)

As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950–Metabolites in Frozen Human Plasma

Externí odkaz: https://doaj.org/article/e757670a32e84af9bc9bad52c975b5dc

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Akademický článek

LipidMatch: an automated workflow for rule-based lipid identification using untargeted high-resolution tandem mass spectrometry data

Autor: Jeremy P. Koelmel, Nicholas M. Kroeger, Candice Z. Ulmer, John A. Bowden, Rainey E. Patterson, Jason A. Cochran, Christopher W. W. Beecher, Timothy J. Garrett, Richard A. Yost

Publikováno v: BMC Bioinformatics, Vol 18, Iss 1, Pp 1-11 (2017)

Abstract Background Lipids are ubiquitous and serve numerous biological functions; thus lipids have been shown to have great potential as candidates for elucidating biomarkers and pathway perturbations associated with disease. Methods expanding cover

Externí odkaz: https://doaj.org/article/24d0b49e7e954a8da7e3dbc92d2574d8

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High-Resolution Mass Spectrometry for the Measurement of PTH and PTH Fragments: Insights into PTH Physiology and Bioactivity

Autor: Candice Z. Ulmer, Kittrawee Kritmetapak, Ravinder J. Singh, Hubert W. Vesper, Rajiv Kumar

Publikováno v: Journal of the American Society of Nephrology. 33:1448-1458

Full-length parathyroid hormone (PTH 1-84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1-84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by PTH immunoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c412ecc835fb7c063ae822087e032a4
https://doi.org/10.1681/asn.2022010036

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Introducing the Lipidomics Minimal Reporting Checklist

Publikováno v: Nature metabolism. 4(9)

The rapid increase in lipidomic data has triggered a community-based movement to develop guidelines and minimum requirements for generating, reporting and publishing lipidomic data. The creation of a dynamic checklist summarizing key details of lipid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adffc26ba492153ea9d529e4516d3b2a
https://pubmed.ncbi.nlm.nih.gov/35934691

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The path to the standardization of PTH

Autor: Candice Z. Ulmer, Konstantinos Makris, Annemieke C. Heijboer, Etienne Cavalier, Samuel Vasikaran, Harjit Pal Bhattoa

Publikováno v: Cavalier, E, Vasikaran, S, Bhattoa, H P, Heijboer, A C, Makris, K & Ulmer, C Z 2021, ' The path to the standardization of PTH : Is this a realistic possibility? a position paper of the IFCC C-BM ', Clinica Chimica Acta, vol. 515, pp. 44-51 . https://doi.org/10.1016/j.cca.2020.12.022
Clinica chimica acta; international journal of clinical chemistry, 515, 44-51. Elsevier
Clinica Chimica Acta, 515, 44-51. Elsevier
Clin Chim Acta

Parathyroid hormone (PTH) determination is of greatest importance for patients suffering from parathyroid gland disorders and for the follow-up of bone turnover in patients suffering from chronic kidney disease (CKD). Two generations of PTH assays ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f0f898a806ada223f6f64b72f2492f
https://doi.org/10.1016/j.cca.2020.12.022

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Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood

Autor: Candice Z. Ulmer, Niklas Rye Jørgensen, Richard Eastell, Konstantinos Makris, Annemieke C. Heijboer, Harjit Pal Bhattoa, Etienne Cavalier, Cyrus Cooper, Samuel Vasikaran, Stuart L. Silverman, John A. Kanis

Publikováno v: Clinica chimica acta; international journal of clinical chemistry, 515, 16-20. Elsevier
Bhattoa, H P, Cavalier, E, Eastell, R, Heijboer, A C, Jørgensen, N R, Makris, K, Ulmer, C Z, Kanis, J A, Cooper, C, Silverman, S L & Vasikaran, S D 2021, ' Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood ', Clinica Chimica Acta, vol. 515, pp. 16-20 . https://doi.org/10.1016/j.cca.2020.12.023
Clin Chim Acta
Clinica Chimica Acta, 515, 16-20. Elsevier

Procollagen type I N-propeptide (PINP) and the C-terminal telopeptide of type I collagen (β-CTX) in blood have been designated as reference bone turnover markers in osteoporosis by the International Osteoporosis Foundation (IOF) and International Fe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba97bde10729592f5baa417a873fa17c
https://doi.org/10.1016/j.cca.2020.12.023

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