Výsledky vyhledávání - "Z, Obradovic"

Akademický článek

Characterization of gene expression and biological pathways in Wilms tumor

Autor: Claire D. Gerall, Aleksandar Z. Obradovic, Madison C. Betcher, Larisa Debelenko, Alice Lee, Matthew C. Dallos, Erica M. Fallon

Publikováno v: Journal of Pediatric Surgery Open, Vol 4, Iss , Pp 100095- (2023)

Background: Although mortality for low stage (I/II) Wilms tumor (WT) has greatly improved with dose-intense multimodality and multi-agent interventions, advanced stage (III/IV) tumors remain associated with relapse, mortality and increased treatment-

Externí odkaz: https://doaj.org/article/f6cc79cd6996434795e8121664219d52

Zobrazit plný text záznamu

Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death

Autor: Joshua H. Choe, Tatsuya Kawase, An Xu, Asja Guzman, Aleksandar Z. Obradovic, Ana Maria Low-Calle, Bita Alaghebandan, Ananya Raghavan, Kaitlin Long, Paul M. Hwang, Joshua D. Schiffman, Yan Zhu, Ruiying Zhao, Dung-Fang Lee, Chen Katz, Carol Prives

Publikováno v: Cancer Discovery. 13:1250-1273

Cancer-relevant mutations in the oligomerization domain (OD) of the p53 tumor suppressor protein, unlike those in the DNA binding domain, have not been well elucidated. Here, we characterized the germline OD mutant p53(A347D), which occurs in cancer-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee3f5faba37fa6f65003b502bf802e04
https://doi.org/10.1158/2159-8290.cd-22-0882

Zobrazit plný text záznamu

Supplementary Figures from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death

Autor: Carol Prives, Chen Katz, Dung-Fang Lee, Ruiying Zhao, Yan Zhu, Joshua D. Schiffman, Paul M. Hwang, Kaitlin Long, Ananya Raghavan, Bita Alaghebandan, Ana Maria Low-Calle, Aleksandar Z. Obradovic, Asja Guzman, An Xu, Tatsuya Kawase, Joshua H. Choe

Supplementary Figures 1-9 demonstrating the GOF and LOF activities of p53(A347D)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc4e592a4f44e9fe8a084a6306927ad
https://doi.org/10.1158/2159-8290.22758948

Zobrazit plný text záznamu

Supplementary Data 2 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death

Differentially expressed genes in U2OS cells varying in p53 allelic status combined from two independent RNA library preparations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e2aea4d4b66c460c14fe8e4f80fb32
https://doi.org/10.1158/2159-8290.22758963

Zobrazit plný text záznamu

Supplementary Data 4 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death

p53 ChIPseq peaks from U2OS cells varying in p53 allelic status

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1e26825ff2f005ddb7a242ea60daca
https://doi.org/10.1158/2159-8290.22758957

Zobrazit plný text záznamu

Supplementary Data 6 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death

p53 ChIPseq peaks from osteoblasts derived from normal and LFS individuals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dc8f31e4f2db187fb94823e375bfac
https://doi.org/10.1158/2159-8290.22758951

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání