Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Z, Kostrouch"'
Autor:
Z, Kostrouch
Publikováno v:
Folia biologica. 66(3)
Publikováno v:
Scopus-Elsevier
CHR3 is a Caenorhabditis elegans orphan nuclear hormone receptor highly homologous to Drosophila DHR3, an ecdysone-inducible gene product involved in metamorphosis. Related vertebrate factors include RORalpha/RZRalpha, RZRbeta and RevErb. Gel-shift s
Publikováno v:
Folia biologica. 57(6)
Nuclear receptors (NRs), or nuclear hormone receptors (NHRs), are transcription factors that regulate development and metabolism of most if not all animal species. Their regulatory networks include conserved mechanisms that are shared in-between spec
Autor:
Z, Kostrouch
Publikováno v:
Folia biologica. 53(6)
Autor:
K, Simecková, E, Brozová, J, Vohánka, M, Pohludka, Z, Kostrouch, M W, Krause, J E, Rall, M, Kostrouchová
Publikováno v:
Folia biologica. 53(3)
The C. elegans genome encodes an unexpectedly large number of NHRs, the majority of which are classified as supplementary nuclear receptors (supnrs) that are likely to have evolved from an ancestral protein related to vertebrate HNF-4. To understand
Autor:
M, Kostrouchová, Z, Kostrouch
Publikováno v:
Folia biologica. 53(2)
Valproic acid (2-propyl pentanoic acid) is a drug used for the treatment of epilepsy and bipolar disorder. Although very rare, side effects such as spina bifida and other defects of neural tube closure indicate that valproic acid interferes with deve
Publikováno v:
Folia biologica. 52(4)
BIR-1 and Survivin are highly conserved members of the inhibitor of apoptosis protein family that regulate cell division in nematodes and mammals and inhibit apoptosis in mammals. In the C. elegans genome, bir-1 is organized in an operon together wit
Autor:
P, Libý, M, Kostrouchová, M, Pohludka, P, Yilma, P, Hrabal, J, Sikora, E, Brozová, J E, Rall, Z, Kostrouch
Publikováno v:
Folia biologica. 52(1-2)
Abnormal expression of histone deacetylases may contribute to the establishment of a cancer specific transcription profile. We examined expression of HDAC3 in human non-malignant gliosis and glial astrocytic tumours. Samples from four non-malignant g
Publikováno v:
Folia biologica. 51(1)
CD44 comprises a family of membrane adhesion molecules encoded by a single gene and diversified by alternative splicing and extensive posttranslational modifications. Alterations of CD44 expression patterns are linked to tumour invasion and formation
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(23)
Nuclear hormone receptors comprise a characteristic family of transcription factors found in vertebrates, insects and nematodes. Here we show by cDNA and gene cloning that a Cnidarian, Tripedalia cystophora , possesses a retinoid receptor (jRXR) with