Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Z, Grunbaum"'
Publikováno v:
Radiation research. 111(2)
Radiolabeled fluoromisonidazole has been characterized as a probe for hypoxic cells in vitro and in vivo. The uptake and retention of [3H]fluoromisonidazole and [3H]misonidazole were compared in V-79 cell monolayers and spheroids by varying incubatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d81875f200428f30a471ca1e7740dcdd
https://pubmed.ncbi.nlm.nih.gov/3628717
https://pubmed.ncbi.nlm.nih.gov/3628717
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 28(1)
Misonidazole is a known hypoxic cell sensitizer that binds covalently in hypoxic cells. Its congeners labeled with 77Br, 75Br, or 18F, are likely candidates for imaging hypoxia. We have synthesized and tested [82Br]-4-bromomisonidazole, [3H]-4-bromom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b28818cbb71faca6b40fa46e904ff263
https://pubmed.ncbi.nlm.nih.gov/3794812
https://pubmed.ncbi.nlm.nih.gov/3794812
Publikováno v:
Journal of the National Cancer Institute. 64(1)
We studied the tumor uptake of [67Ga]citrate, [59Fe]citrate, and 125I-labeled transferrin (TF) by the in vitro growth form of EMT-6, a sarcoma-like mammary tumor of BALB/c mice. In analyzing the binding experiments, we developed a new mathematical mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f0c3c738dcf2445ea1f3c5c6a5db31c
https://pubmed.ncbi.nlm.nih.gov/6243376
https://pubmed.ncbi.nlm.nih.gov/6243376
Publikováno v:
Radiation research. 102(1)
3-Amino-2-hydroxypropyl phosphorothioate (WR77913), a less toxic phosphorothioate radioprotector than WR2721, has been labeled with 35S. The biodistribution of a radioprotective dose of 800 mg/kg was determined in C3H mice bearing RIF-1 tumors as a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0c8a7a0bc00d0cac4b52989ca8b4369
https://pubmed.ncbi.nlm.nih.gov/2984715
https://pubmed.ncbi.nlm.nih.gov/2984715
Autor:
S M, Larson, P L, Weiden, Z, Grunbaum, H G, Kaplan, J S, Rasey, M M, Graham, G E, Sale, G D, Harp, D L, Williams
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 22(10)
Uptake of [3H]2-deoxyglucose was studied in BALB/c mice with EMT-6 sarcoma, in Buffalo rats with Morris 7777 hepatoma, and in eight dogs with spontaneous neoplasms: five osteosarcomas and three diffuse lymphomas. High tumor-to-tissue ratios were obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85c566e079303c3399b09cb968528233
https://pubmed.ncbi.nlm.nih.gov/6974768
https://pubmed.ncbi.nlm.nih.gov/6974768
Autor:
S M, Larson, P L, Weiden, Z, Grunbaum, J S, Rasey, H G, Kaplan, M M, Graham, G D, Harp, G E, Sale, D L, Williams
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 22(10)
Uptake [3H] thymidine was studied in BALB/c mice with EMT-6 sarcoma, in Buffalo rats with Morris 7777 hepatoma, and in nine dogs with spontaneous neoplasms: four lymphomas, two osteosarcomas, two soft-tissue sarcomas, and a thyroid carcinoma. High tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39184afaa05e2eb02a8bc7116ee405b7
https://pubmed.ncbi.nlm.nih.gov/6974767
https://pubmed.ncbi.nlm.nih.gov/6974767
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 20(8)
The EMT-6 sarcoma-like tumor of BALB/c mice can be grown as a solid subcutaneous transplantable tumor in vivo or as a monolayer culture in vitro. We have studied the uptake of gallium-67 by this tumor growing subcutaneously on the backs of 6-week-old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24632c0afc50adafa878526c05b07a5d
https://pubmed.ncbi.nlm.nih.gov/541731
https://pubmed.ncbi.nlm.nih.gov/541731
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 25(7)
Uptake of H-3 thymidine was studied in mice, both normal and with spontaneous lymphoma, and in the organs and tumors of dogs with spontaneous tumors. Uptake was compared with relative blood flow as measured by the distribution of C-14 iodoantipyrine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd3dba7e00d48a9198bb49f38c37a163
https://pubmed.ncbi.nlm.nih.gov/6610731
https://pubmed.ncbi.nlm.nih.gov/6610731
Publikováno v:
Radiation research. 102(1)
[14C]Bromomisonidazole was prepared by direct bromination of [ring-2] [14C]misonidazole in dioxane. The uptake and binding of the two labeled sensitizers were compared in vitro in 1-mm EMT-6 spheroids which contain a necrotic core. Using liquid scint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa7264cbd18e7ea9608298561f107a0c
https://pubmed.ncbi.nlm.nih.gov/3983371
https://pubmed.ncbi.nlm.nih.gov/3983371
Publikováno v:
Radiation research. 101(3)
Uptake of [2-ring-14C]misonidazole and [3H]misonidazole with tritium in the side chain has been compared in 1-mm EMT-6/UW spheroids using liquid scintillation counting and autoradiography. The uptake of both labeled sensitizers as a function of incub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35fac565002f3e4cb7a30892027cd974
https://pubmed.ncbi.nlm.nih.gov/3983363
https://pubmed.ncbi.nlm.nih.gov/3983363