Zobrazeno 1 - 10 of 88 pro vyhledávání: '"Yw, Kow"'
1
New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase
Autor: Hatahet Z, Yw, Kow, Aa, Purmal, Rp, Cunningham, Susan S. Wallace
Publikováno v: Europe PubMed Central
5-Hydroxy-2'-deoxycytidine (5-OHdC) and 5-hydroxy-2'-deoxyuridine (5-OHdU) are major products of oxidative DNA damage with mutagenic potential. Until now, no enzymatic activity responsible for their removal has been identified. We report here that bo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::08227466280272749f03e80740d7daaa
https://pubmed.ncbi.nlm.nih.gov/8034633
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2
Processing of model single-strand breaks in phi X-174 RF transfecting DNA by Escherichia coli
Autor: Yw, Kow, Faundez G, Rj, Melamede, Susan S. Wallace
Publikováno v: Europe PubMed Central
The inactivation efficiency and repair of single-strand breaks was investigated using model strand breaks created by endonucleolytic incision of damaged DNA. Phi X-174 duplex transfecting DNA containing either thymine glycols, urea residues, or abasi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::77635e84b47404921b91983320a2737b
https://pubmed.ncbi.nlm.nih.gov/1852023
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3
Methylperoxyl radicals as intermediates in the damage to DNA irradiated in aqueous dimethyl sulfoxide with gamma rays
Autor: Jr, Milligan, Jy, Ng, Cc, Wu, Ja, Aguilera, Jf, Ward, Yw, Kow, Susan S. Wallace, Rp, Cunningham
Publikováno v: Europe PubMed Central
Using agarose gel electrophoresis, we have measured the yields of DNA single-strand breaks (SSBs) for plasmid DNA gamma-irradiated in aerobic aqueous solution. Incubation after irradiation with the base damage repair endonucleases formamidopyrimidine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9cfbb3f84a7787394e1b3f07d1cf2050
http://europepmc.org/abstract/med/8927715
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4
Uracil DNA N-glycosylase distributively interacts with duplex polynucleotides containing repeating units of either TGGCCAAGCU or TGGCCAAGCTTGGCCAAGCU
Autor: Aa, Purmal, Gw, Lampman, Ei, Pourmal, Rj, Melamede, Susan S. Wallace, Yw, Kow
Publikováno v: Europe PubMed Central
Uracil DNA N-glycosylase (UDG) has been used as a model enzyme to test a novel universal approach to discriminate between two possible enzymatic mechanisms of specific site location in DNA, processive (DNA-scanning mechanism) and distributive (random
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cf904960de43faa379bcff7e8883e81a
http://europepmc.org/abstract/med/8071327
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5
Akademický článek
Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans.
Autor: Flood CL; Department of Biology, Emory University, Atlanta, Georgia, United States of America., Rodriguez GP; Department of Biology, Emory University, Atlanta, Georgia, United States of America., Bao G; Department of Radiation Oncology, Emory University, Atlanta, Georgia, United States of America., Shockley AH; Department of Biology, Emory University, Atlanta, Georgia, United States of America., Kow YW; Department of Radiation Oncology, Emory University, Atlanta, Georgia, United States of America; Winship Cancer Institute, Emory University, Atlanta, Georgia, United States of America., Crouse GF; Department of Biology, Emory University, Atlanta, Georgia, United States of America; Winship Cancer Institute, Emory University, Atlanta, Georgia, United States of America.
Publikováno v: PLoS genetics [PLoS Genet] 2015 Mar 05; Vol. 11 (3), pp. e1005049. Date of Electronic Publication: 2015 Mar 05 (Print Publication: 2015).
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6
Akademický článek
Inactivation of a common OGG1 variant by TNF-alpha in mammalian cells.
Autor: Morreall J; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA; Graduate Program in Genetics and Molecular Biology, Emory University, Atlanta, GA, 30322, USA., Limpose K; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA; Graduate Program in Cancer Biology, Emory University, Atlanta, GA, 30322, USA., Sheppard C; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA., Kow YW; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA., Werner E; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA., Doetsch PW; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA; Emory Winship Cancer Institute, Emory University, Atlanta, GA, 30322, USA; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA. Electronic address: medpwd@emory.edu.
Publikováno v: DNA repair [DNA Repair (Amst)] 2015 Feb; Vol. 26, pp. 15-22. Date of Electronic Publication: 2014 Dec 04.
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7
Akademický článek
The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity.
Autor: Hong S; Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA; Molecular and Systems Pharmacology Graduate Program, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA. Electronic address: shong27@emory.edu., Hashimoto H; Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA. Electronic address: hhashi3@emory.edu., Kow YW; Department of Radiation Oncology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA. Electronic address: ykow@emory.edu., Zhang X; Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA. Electronic address: xzhan02@emory.edu., Cheng X; Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA. Electronic address: xcheng@emory.edu.
Publikováno v: Journal of molecular biology [J Mol Biol] 2014 Nov 11; Vol. 426 (22), pp. 3703-3712. Date of Electronic Publication: 2014 Sep 21.
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8
Akademický článek
Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base.
Autor: Pande P; Department of Chemistry, University of Connecticut, Storrs, CT 06269, USA., Das RS, Sheppard C, Kow YW, Basu AK
Publikováno v: DNA repair [DNA Repair (Amst)] 2012 Nov 01; Vol. 11 (11), pp. 926-31. Date of Electronic Publication: 2012 Oct 10.
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9
Akademický článek
Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans.
Autor: Morris LP; Program in Genetics and Molecular Biology, Graduate Division of Biological and Biomedical Sciences, James T. Laney School of Graduate Studies, Emory University, USA., Degtyareva N, Sheppard C, Heyburn L, Ivanov AA, Kow YW, Doetsch PW
Publikováno v: DNA repair [DNA Repair (Amst)] 2012 Sep 01; Vol. 11 (9), pp. 753-65. Date of Electronic Publication: 2012 Jul 19.
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10
Akademický článek
Human endonuclease V as a repair enzyme for DNA deamination.
Autor: Mi R; Department of Genetics and Biochemistry, South Carolina Experiment Station, Clemson University, Room 219 Biosystems Research Complex, 105 Collings Street, Clemson, SC 29634, United States., Alford-Zappala M, Kow YW, Cunningham RP, Cao W
Publikováno v: Mutation research [Mutat Res] 2012 Jul 01; Vol. 735 (1-2), pp. 12-8. Date of Electronic Publication: 2012 Jun 01.
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