Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yvonne Y. Y. Lai"'
Autor:
Le Li, Alden King-Yung Leung, Tsz-Piu Kwok, Yvonne Y. Y. Lai, Iris K. Pang, Grace Tin-Yun Chung, Angel C. Y. Mak, Annie Poon, Catherine Chu, Menglu Li, Jacob J. K. Wu, Ernest T. Lam, Han Cao, Chin Lin, Justin Sibert, Siu-Ming Yiu, Ming Xiao, Kwok-Wai Lo, Pui-Yan Kwok, Ting-Fung Chan, Kevin Y. Yip
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Abstract We present a new method, OMSV, for accurately and comprehensively identifying structural variations (SVs) from optical maps. OMSV detects both homozygous and heterozygous SVs, SVs of various types and sizes, and SVs with or without creating
Externí odkaz:
https://doaj.org/article/fd1335bc468d46e4a3782b73f0fe7dac
Autor:
Pui-Yan Kwok, Elio Schijlen, James W. Hicks, Katherine S. Pollard, Marie Altmanová, Alex I. Makunin, Tomaso Patarnello, Petr Velenský, Michail Rovatsos, Yulia Mostovoy, Alisha K. Holloway, Vladimir A. Trifonov, Valerio Orlandini, Yvonne Y. Y. Lai, Marco Fondi, Massimo Milan, Ivan Rehák, Renato Fani, I. G. Kichigin, Lukáš Kratochvíl, Benoit G. Bruneau, Alessio Iannucci, Claudio Ciofi, Martina Johnson Pokorná, Tim S. Jessop, Oliver A. Ryder, Walter L. Eckalbar, Angel C.Y. Mak, Abigail L. Lind, Joseph R. Mendelson
Publikováno v:
Nature ecology & evolution, vol 3, iss 8
Nature ecology & evolution
Nature Ecology and Evolution 3 (2019) 8
Nature Ecology and Evolution, 3(8), 1241-1252
Nature ecology & evolution
Nature Ecology and Evolution 3 (2019) 8
Nature Ecology and Evolution, 3(8), 1241-1252
Monitor lizards are unique among ectothermic reptiles in that they have high aerobic capacity and distinctive cardiovascular physiology resembling that of endothermic mammals. Here, we sequence the genome of the Komodo dragon Varanus komodoensis, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd9768187f3dbbc526728997db02150
https://doi.org/10.1038/s41559-019-0945-8
https://doi.org/10.1038/s41559-019-0945-8
Autor:
Pui-Yan Kwok, Le Li, Melissa Chun-Jiao Liu, Yvonne Y. Y. Lai, Alden King-Yung Leung, Pak-Leung Ho, Ting-Fung Chan, Catherine J. Chu, Kevin Y. Yip
Publikováno v:
GigaScience
GigaScience, vol 8, iss 7
GigaScience, vol 8, iss 7
Background Optical mapping is an emerging technology that complements sequencing-based methods in genome analysis. It is widely used in improving genome assemblies and detecting structural variations by providing information over much longer (up to 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64f04d51412210eef5adc7f597aa2a4
https://pubmed.ncbi.nlm.nih.gov/31289833
https://pubmed.ncbi.nlm.nih.gov/31289833
Autor:
Iris K. Pang, Alden King-Yung Leung, Tsz-Piu Kwok, Ming Xiao, Le Li, Pui-Yan Kwok, Siu-Ming Yiu, Angel C.Y. Mak, Grace Tin Yun Chung, Han Cao, Yvonne Y. Y. Lai, Menglu Li, Kwok Wai Lo, Chin Lin, Ernest T. Lam, Kevin Y. Yip, Justin Sibert, Catherine Chu, Ting-Fung Chan, Jacob J. K. Wu, Annie Poon
Publikováno v:
Genome biology, vol 18, iss 1
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Human genomes contain structural variations (SVs) that are associated with various phenotypic variations and diseases. SV detection by sequencing is incomplete due to limited read length. Nanochannel-based optical mapping (OM) allows direct observati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324fbfab90f82ddcf18cdb6f905d8826
https://doi.org/10.1186/s13059-017-1356-2
https://doi.org/10.1186/s13059-017-1356-2
Autor:
Andy Wing Chun Pang, Yvonne Y. Y. Lai, Yulia Mostovoy, Heng Dai, Justin Sibert, Pui-Yan Kwok, Ernest T. Lam, Catherine M. L. Li, William Stedman, Željko Džakula, Siu-Ming Yiu, Jacob J. K. Wu, Thomas Anantharaman, Han Cao, Ting-Fung Chan, Aldrin Kay-Yuen Yim, Warren Andrews, Alex Hastie, Chin Lin, Saki Chan, Angel C.Y. Mak, Catherine Chu, Tsz-Piu Kwok, Annie Poon, Kevin Y. Yip, Ming Xiao, Alden King-Yung Leung, Xiang Zhou, Jing-Woei Li
Publikováno v:
Genetics, vol 202, iss 1
Genetics
Genetics
Comprehensive whole-genome structural variation detection is challenging with current approaches. With diploid cells as DNA source and the presence of numerous repetitive elements, short-read DNA sequencing cannot be used to detect structural variati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9d8739f1ee024da140da1ab8c8a893
https://doi.org/10.1534/genetics.115.183483
https://doi.org/10.1534/genetics.115.183483
Autor:
David P. Astling, Veronica B. Searles, Tina Graves, Pui-Yan Kwok, James M. Sikela, Majesta O'Bleness, Yvonne Y. Y. Lai, Richard K. Wilson, C. Michael Dickens, Derek Albracht, Angel C.Y. Mak, Catherine Chu, Chin Lin
Publikováno v:
BMC genomics, vol 15, iss 1
BMC Genomics
BMC Genomics
Background Although the reference human genome sequence was declared finished in 2003, some regions of the genome remain incomplete due to their complex architecture. One such region, 1q21.1-q21.2, is of increasing interest due to its relevance to hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b462577b81abaa2aac4e2b8fdc4a623
https://doi.org/10.1186/1471-2164-15-387
https://doi.org/10.1186/1471-2164-15-387