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pro vyhledávání: '"Yvonne Woitzat"'
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans
Autor:
Samim Sharifi, Prerana Chaudhari, Asya Martirosyan, Alexander Otto Eberhardt, Finja Witt, André Gollowitzer, Lisa Lange, Yvonne Woitzat, Eberechukwu Maryann Okoli, Huahui Li, Norman Rahnis, Joanna Kirkpatrick, Oliver Werz, Alessandro Ori, Andreas Koeberle, Holger Bierhoff, Maria Ermolaeva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Ribosome biogenesis is initiated by RNA polymerase I (Pol I)-mediated synthesis of pre-ribosomal RNA (pre-rRNA). Pol I activity was previously linked to longevity, but the underlying mechanisms were not studied beyond effects on nucleolar st
Externí odkaz:
https://doaj.org/article/e8c06c7d253c4ce7a8ddf6f0c29bac62
