Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yvonne Richaud"'
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102445- (2021)
Germline heterozygous GATA2 mutations underlie a complex disorder characterized by bone marrow failure, immunodeficiency and high risk to develop myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Our understanding about GATA2 deficienc
Externí odkaz:
https://doaj.org/article/620d1103049b4a9789e18ced1e1491c5
Autor:
Meritxell Carrió, Helena Mazuelas, Yvonne Richaud-Patin, Bernat Gel, Ernest Terribas, Imma Rosas, Senda Jimenez-Delgado, Josep Biayna, Leen Vendredy, Ignacio Blanco, Elisabeth Castellanos, Conxi Lázaro, Ángel Raya, Eduard Serra
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 411-426 (2019)
Summary: Neurofibromatosis type 1 (NF1) is a tumor predisposition genetic disease caused by mutations in the NF1 tumor suppressor gene. Plexiform neurofibromas (PNFs) are benign Schwann cell (SC) tumors of the peripheral nerve sheath that develop thr
Externí odkaz:
https://doaj.org/article/88a77f9a7c3e4807b0539d76fcbde7b1
Autor:
Angelique di Domenico, Giulia Carola, Carles Calatayud, Meritxell Pons-Espinal, Juan Pablo Muñoz, Yvonne Richaud-Patin, Irene Fernandez-Carasa, Marta Gut, Armida Faella, Janani Parameswaran, Jordi Soriano, Isidro Ferrer, Eduardo Tolosa, Antonio Zorzano, Ana Maria Cuervo, Angel Raya, Antonella Consiglio
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 213-229 (2019)
Summary: Parkinson's disease (PD) is associated with the degeneration of ventral midbrain dopaminergic neurons (vmDAns) and the accumulation of toxic α-synuclein. A non-cell-autonomous contribution, in particular of astrocytes, during PD pathogenesi
Externí odkaz:
https://doaj.org/article/70aa8260cb6b4833930f331560a354aa
Autor:
Cristina Olgasi, Maria Talmon, Simone Merlin, Alessia Cucci, Yvonne Richaud-Patin, Gabriella Ranaldo, Donato Colangelo, Federica Di Scipio, Giovanni N. Berta, Chiara Borsotti, Federica Valeri, Francesco Faraldi, Maria Prat, Maria Messina, Piercarla Schinco, Angelo Lombardo, Angel Raya, Antonia Follenzi
Publikováno v:
Stem Cell Reports, Vol 11, Iss 6, Pp 1391-1406 (2018)
Summary: We generated patient-specific disease-free induced pluripotent stem cells (iPSCs) from peripheral blood CD34+ cells and differentiated them into functional endothelial cells (ECs) secreting factor VIII (FVIII) for gene and cell therapy appro
Externí odkaz:
https://doaj.org/article/8867c765fe344630b78a3afcd6aa23de
Autor:
Rubén Fernández‐Santiago, Iria Carballo‐Carbajal, Giancarlo Castellano, Roger Torrent, Yvonne Richaud, Adriana Sánchez‐Danés, Roser Vilarrasa‐Blasi, Alex Sánchez‐Pla, José Luis Mosquera, Jordi Soriano, José López‐Barneo, Josep M Canals, Jordi Alberch, Ángel Raya, Miquel Vila, Antonella Consiglio, José I Martín‐Subero, Mario Ezquerra, Eduardo Tolosa
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 12, Pp 1529-1546 (2015)
Abstract The epigenomic landscape of Parkinson's disease (PD) remains unknown. We performed a genomewide DNA methylation and a transcriptome studies in induced pluripotent stem cell (iPSC)‐derived dopaminergic neurons (DAn) generated by cell reprog
Externí odkaz:
https://doaj.org/article/007509ba6a4d4d19940a0fff72f98b85
Autor:
Isaac Canals, Jordi Soriano, Javier G. Orlandi, Roger Torrent, Yvonne Richaud-Patin, Senda Jiménez-Delgado, Simone Merlin, Antonia Follenzi, Antonella Consiglio, Lluïsa Vilageliu, Daniel Grinberg, Angel Raya
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 546-557 (2015)
Induced pluripotent stem cell (iPSC) technology has been successfully used to recapitulate phenotypic traits of several human diseases in vitro. Patient-specific iPSC-based disease models are also expected to reveal early functional phenotypes, altho
Externí odkaz:
https://doaj.org/article/41412330940d4205b3aa8f678df1978c
Autor:
Meritxell Pons-Espinal, Lucas Blasco-Agell, Irene Fernandez-Carasa, Angelique di Domenico, Yvonne Richaud, Jose Luis Mosquera, Laura Marruecos, Lluís Espinosa, Alicia Garrido, Eduardo Tolosa, Michael J. Edel, Manel Juan Otero, Isidre Ferrer, Angel Raya, Antonella Consiglio
Parkinson’s disease (PD) is associated with premature death of dopamine-producing neurons in the brain. Previous studies have shown that astrocytes of PD patients may contribute to neuronal degeneration by mechanisms involving both direct cell-to-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2bb968ae16b7e22844716570ce0bf65
https://doi.org/10.1101/2022.08.23.504918
https://doi.org/10.1101/2022.08.23.504918
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Stem Cell Research, Vol 55, Iss, Pp 102445-(2021)
Universidad de Barcelona
Stem Cell Research, Vol 55, Iss, Pp 102445-(2021)
Germline heterozygous GATA2 mutations underlie a complex disorder characterized by bone marrow failure, immunodeficiency and high risk to develop myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Our understanding about GATA2 deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd686d982912949f339e0f3a7bb30d7d
http://hdl.handle.net/2445/181015
http://hdl.handle.net/2445/181015
Autor:
Maria Messina, Alessia Cucci, Federica Di Scipio, Antonia Follenzi, Giovanni Nicolao Berta, Simone Merlin, Angel Raya, Donato Colangelo, Federica Valeri, Cristina Olgasi, Chiara Borsotti, Piercarla Schinco, Francesco Faraldi, Gabriella Ranaldo, Maria Talmon, Maria Prat, Angelo Lombardo, Yvonne Richaud-Patin
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 11, Iss 6, Pp 1391-1406 (2018)
Stem Cell Reports, Vol 11, Iss 6, Pp 1391-1406 (2018)
Summary We generated patient-specific disease-free induced pluripotent stem cells (iPSCs) from peripheral blood CD34+ cells and differentiated them into functional endothelial cells (ECs) secreting factor VIII (FVIII) for gene and cell therapy approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c842671561c5d316f5bf6f97e9aa794
https://doi.org/10.1016/j.stemcr.2018.10.012
https://doi.org/10.1016/j.stemcr.2018.10.012
Autor:
Daniel Malagarriga, Meritxell Pons-Espinal, Carles Calatayud, Antonella Consiglio, Eduard Tolosa, Irene Fernandez-Carasa, E Molina, Giulia Carola, Patrizia Dell'Era, Angel Raya, V Baruffi, Yvonne Richaud-Patin, J J Toledo-Aral, Jordi Soriano, Alysson R. Muotri, J. Garcia Ojalvo, S Beltramone, L Blasco-Agell
Publikováno v:
NPJ Parkinson's Disease
NPJ Parkinson's disease, vol 7, iss 1
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
NPJ Parkinson's disease, vol 7, iss 1
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
A deeper understanding of early disease mechanisms occurring in Parkinson’s disease (PD) is needed to reveal restorative targets. Here we report that human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons (DAn) obtained from health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c71b2a76cc565b24ff934aca2dd988f
https://pubmed.ncbi.nlm.nih.gov/34215735
https://pubmed.ncbi.nlm.nih.gov/34215735