Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits.

Autor: Jenny Ibach, Yvonne Radon, Márton Gelléri, Michael H Sonntag, Luc Brunsveld, Philippe I H Bastiaens, Peter J Verveer

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0143162 (2015)

Signaling from the epidermal growth factor receptor (EGFR) via phosphorylation on its C-terminal tyrosine residues requires self-association, which depends on the diffusional properties of the receptor and its density in the plasma membrane. Dimeriza

Externí odkaz: https://doaj.org/article/5356e206125a44ed8eb6bdeeed260bac

Co-imaging extrinsic, intrinsic and effector caspase activity by fluorescence anisotropy microscopy

Autor: Piotr Liguzinski, Philippe I. H. Bastiaens, Hernán E. Grecco, Peter J. Verveer, Klaus C. Schuermann, Yvonne Radon, Agustín A. Corbat

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Redox Biology, Vol 19, Iss, Pp 210-217 (2018)
Redox Biology

In order to overcome intercellular variability and thereby effectively assess signal propagation in biological networks it is imperative to simultaneously quantify multiple biological observables in single living cells. While fluorescent biosensors h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e6f8b25433ca71cc57e62b62f48570
https://www.sciencedirect.com/science/article/pii/S2213231718305524

A Bayesian mixture model to quantify parameters of spatial clustering

Autor: Peter J. Verveer, Sabrina Herrmann, Katja Ickstadt, Holger Schwender, Martin Schäfer, Thomas Klein, Yvonne Radon

Publikováno v: Computational Statistics & Data Analysis. 92:163-176

A new Bayesian approach for quantifying spatial clustering is proposed that employs a mixture of gamma distributions to model the squared distance of points to their second nearest neighbors. The method is designed to answer questions arising in biop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::300c3de9e55f918da24e9c60466835c2
https://doi.org/10.1016/j.csda.2015.07.004

Conserved Roles of the Prion Protein Domains on Subcellular Localization and Cell-Cell Adhesion

Autor: Claudia A. O. Stuermer, Edward Málaga-Trillo, Gonzalo P. Solis, Yvonne Radon, Katharina Jechow, Emily Sempou

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e70327 (2013)

Analyses of cultured cells and transgenic mice expressing prion protein (PrP) deletion mutants have revealed that some properties of PrP -such as its ability to misfold, aggregate and trigger neurotoxicity- are controlled by discrete molecular determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251ed1181ae9e27308fca8b11369b93d
https://doi.org/10.1371/journal.pone.0070327