Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Yvonne McCarthy"'
Autor:
Desmond M Murphy, B J Plant, Joseph A Eustace, Parniya Arooj, David V Morrissy, Yvonne McCarthy, Tamara Vagg, Mairead McCarthy, Claire Fleming, Mary Daly
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background Previous studies showed that the combination of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector and potentiator, lumacaftor–ivacaftor (LUMA–IVA) provides meaningful clinical benefits in patients with cystic fibrosi
Externí odkaz:
https://doaj.org/article/49db3130031441878d029412e4fb451a
Autor:
Owen Cronin, Wiley Barton, Carthage Moran, Donal Sheehan, Ronan Whiston, Helena Nugent, Yvonne McCarthy, Catherine B. Molloy, Orla O’Sullivan, Paul D. Cotter, Michael G. Molloy, Fergus Shanahan
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Overweight and metabolic problems now add to the burden of illness in patients with Inflammatory Bowel Disease. We aimed to determine if a program of aerobic and resistance exercise could safely achieve body composition changes in
Externí odkaz:
https://doaj.org/article/0e2af7649ba8478e820d13859ed58207
Autor:
Aileen O'Connell, Shi-Qi An, Yvonne McCarthy, Fabian Schulte, Karsten Niehaus, Yong-Qiang He, Ji-Liang Tang, Robert P. Ryan, J. Maxwell Dow
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 26, Iss 10, Pp 1131-1137 (2013)
The black rot pathogen Xanthomonas campestris utilizes molecules of the diffusible signal factor (DSF) family as signals to regulate diverse processes contributing to virulence. DSF signal synthesis and transduction requires proteins encoded by the r
Externí odkaz:
https://doaj.org/article/8aef22c479cc4ccf9db9df41cd40a295
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1004986 (2015)
Many pathogenic bacteria use cell-cell signaling systems involving the synthesis and perception of diffusible signal molecules to control virulence as a response to cell density or confinement to niches. Bacteria produce signals of diverse structural
Externí odkaz:
https://doaj.org/article/37781293d67b403a804aab946f67e64a
Autor:
Shi-qi An, Delphine L Caly, Yvonne McCarthy, Sarah L Murdoch, Joseph Ward, Melanie Febrer, J Maxwell Dow, Robert P Ryan
Publikováno v:
PLoS Pathogens, Vol 10, Iss 10, p e1004429 (2014)
Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions thr
Externí odkaz:
https://doaj.org/article/4c4453fdc67d458f87f6cb52e9ffafd3
Autor:
Kate B Twomey, Mark Alston, Shi-Qi An, Oisin J O'Connell, Yvonne McCarthy, David Swarbreck, Melanie Febrer, J Maxwell Dow, Barry J Plant, Robert P Ryan
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82432 (2013)
Chronic polymicrobial infections of the lung are the foremost cause of morbidity and mortality in cystic fibrosis (CF) patients. The composition of the microbial flora of the airway alters considerably during infection, particularly during patient ex
Externí odkaz:
https://doaj.org/article/a18b392736e342cbb21006d07fd8d0a3
Autor:
Xiu-Hong Lu, Shi-Qi An, Dong-Jie Tang, Yvonne McCarthy, Ji-Liang Tang, John Maxwell Dow, Robert P Ryan
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52646 (2012)
Biofilm formation and dispersal in the black rot pathogen Xanthomonas campestris pathovar campestris (Xcc) is influenced by a number of factors. The extracellular mannanase ManA has been implicated in biofilm dispersal whereas biofilm formation requi
Externí odkaz:
https://doaj.org/article/da6796a301d7427cbcb131d8502f6202
Autor:
Heather Pearl McLaughlin, Delphine L Caly, Yvonne McCarthy, Robert Patrick Ryan, John Maxwell Dow
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42205 (2012)
The synthesis of virulence factors by pathogenic bacteria is highly regulated and occurs in response to diverse environmental cues. An array of two component systems (TCSs) serves to link perception of different cues to specific changes in gene expre
Externí odkaz:
https://doaj.org/article/8812fe9fbb3949f48b453c3574dd012e
Autor:
Deirdre Gilpin, Barry J. Plant, Fergus Shanahan, J. Stuart Elborn, David Mullane, Joseph A. Eustace, Gisli G. Einarsson, N.J. Ronan, D. Mooney, M. Mccarthy, Desmond M. Murphy, Muireann NiChroinin, Michael M. Tunney, C. McGettigan, Yvonne McCarthy
Publikováno v:
Einarsson, G G, Ronan, N J, Mooney, D, McGettigan, C, Mullane, D, NiChroinin, M, Shanahan, F, Murphy, D M, McCarthy, M, McCarthy, Y, Eustace, J A, Gilpin, D F, Elborn, J S, Plant, B J & Tunney, M M 2021, ' Extended-culture and culture-independent molecular analysis of the airway microbiota in cystic fibrosis following CFTR modulation with ivacaftor ', Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society . https://doi.org/10.1016/j.jcf.2020.12.023
BACKGROUND: Treatment with Ivacaftor provides a significant clinical benefit in people with cystic fibrosis (PWCF) with the class III G551D-CFTR mutation. This study determined the effect of CFTR modulation with ivacaftor on the lung microbiota in PW