Výsledky vyhledávání - "Yvonne M H Bruls"

Akademický článek

Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T

Autor: Julian Mevenkamp, Yvonne M. H. Bruls, Rodrigo Mancilla, Lotte Grevendonk, Joachim E. Wildberger, Kim Brouwers, Matthijs K. C. Hesselink, Patrick Schrauwen, Joris Hoeks, Riekelt H. Houtkooper, Mijke Buitinga, Robin A. de Graaf, Lucas Lindeboom, Vera B. Schrauwen-Hinderling

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract NADH and NAD+ act as electron donors and acceptors and NAD+ was shown to stimulate mitochondrial biogenesis and metabolic health. We here develop a non-invasive Phosphorous Magnetic Resonance Spectroscopy (31P-MRS) method to quantify these m

Externí odkaz: https://doaj.org/article/641cc9cbaffb4da5a60ddf4d1b9cf383

Zobrazit plný text záznamu

Akademický článek

Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial

Autor: Sten M. M. van Beek, Yvonne M. H. Bruls, Froukje Vanweert, Ciarán E. Fealy, Niels J. Connell, Gert Schaart, Esther Moonen-Kornips, Johanna A. Jörgensen, Frédéric M. Vaz, Ellen T. H. C. Smeets, Peter J. Joris, Anne Gemmink, Riekelt H. Houtkooper, Matthijs K. C. Hesselink, Tore Bengtsson, Bas Havekes, Patrick Schrauwen, Joris Hoeks

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

β2-agonist treatment improves skeletal muscle glucose uptake and whole-body glucose homeostasis in rodents. Here the authors report that two-weeks of treatment with the β2-agonist clenbuterol improves insulin-stimulated glucose disposal in healthy

Externí odkaz: https://doaj.org/article/c70a9895a6d34e0086372025f6878383

Zobrazit plný text záznamu

Akademický článek

Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

Autor: Kay H. M. Roumans, Lucas Lindeboom, Pandichelvam Veeraiah, Carlijn M. E. Remie, Esther Phielix, Bas Havekes, Yvonne M. H. Bruls, Martijn C. G. J. Brouwers, Marcus Ståhlman, Marjan Alssema, Harry P. F. Peters, Renée de Mutsert, Bart Staels, Marja-Riitta Taskinen, Jan Borén, Patrick Schrauwen, Vera B. Schrauwen-Hinderling

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Here, the authors use 1H-MRS methodology to show hepatic SFA fraction is a measure o

Externí odkaz: https://doaj.org/article/2c9a2f8b1cf44a76b5b73a890bc8f73e

Zobrazit plný text záznamu

Akademický článek

L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility.

Autor: Yvonne M H Bruls, Yvo J M Op den Kamp, Esther Phielix, Lucas Lindeboom, Bas Havekes, Gert Schaart, Esther Moonen-Kornips, Joachim E Wildberger, Matthijs K C Hesselink, Patrick Schrauwen, Vera B Schrauwen-Hinderling

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0239506 (2020)

BackgroundLow carnitine status may underlie the development of insulin resistance and metabolic inflexibility. Intravenous lipid infusion elevates plasma free fatty acid (FFA) concentration and is a model for simulating insulin resistance and metabol

Externí odkaz: https://doaj.org/article/3aa7b54fb6b249e0a6e6904ab28a4607

Zobrazit plný text záznamu

Plný text ve formátu HTML

Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function

Autor: Kenneth Meijer, Niels J. Connell, Patrick Schrauwen, Johanna A. Jörgensen, Ciaran E. Fealy, M. C. E. Bragt, L. Bilet, Gert Schaart, J. de Vogel-van den Bosch, J. Mevenkamp, Vera B. Schrauwen-Hinderling, Lotte Grevendonk, Christopher McCrum, Esther Moonen-Kornips, Joris Hoeks, Yvonne M. H. Bruls, Bas Havekes

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications, 12(1):4773. Nature Publishing Group

The relationship between the age-associated decline in mitochondrial function and its effect on skeletal muscle physiology and function remain unclear. In the current study, we examined to what extent physical activity contributes to the decline in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62236b39f309f9f4cc91b561eb4689e
https://doaj.org/article/035190f53f0041ab9013b063d3712f34

Zobrazit plný text záznamu

No evidence for brown adipose tissue activation after creatine supplementation in adult vegetarians

Autor: Wouter D. van Marken-Lichtenbelt, Charlotte Andriessen, Niels J. Connell, Yvonne M. H. Bruls, Daniel Doligkeit, Lawrence Kazak, Tineke van de Weijer, Patrick Schrauwen, Joris Hoeks, Vera B. Schrauwen-Hinderling, Bruce M. Spiegelman, Esther Kornips-Moonen, Bas Havekes

Publikováno v: Nature Metabolism, 3(1), 107-117. Nature Publishing Group

Creatine availability is known to affect creatine-driven thermogenesis in mice. Here Connell et al. report data from a clinical trial in which daily creatine supplementation, perhaps surprisingly, did not alter thermogenesis in adults with otherwise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56a371b10afac62b1aae97d5e0ac34e
https://doi.org/10.1038/s42255-020-00332-0

Zobrazit plný text záznamu

Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

Autor: Marcus Ståhlman, Patrick Schrauwen, Carlijn M. E. Remie, Pandichelvam Veeraiah, Martijn C. G. J. Brouwers, Bas Havekes, Yvonne M. H. Bruls, Vera B. Schrauwen-Hinderling, Esther Phielix, Renée de Mutsert, Marja-Riitta Taskinen, Kay H. M. Roumans, Lucas Lindeboom, Jan Borén, Bart Staels, Marjan Alssema, Harry P. F. Peters

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.1891. ⟨10.1038/s41467-020-15684-0⟩
Nature Communications, 11(1):1891. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1891. ⟨10.1038/s41467-020-15684-0⟩
Nature Communications, 11(1). NATURE PUBLISHING GROUP

Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Hepatic saturated fatty acids (SFA) may be a marker of DNL and are suggested to be m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4cda44b40f970388e986453b2c16b6
https://doaj.org/article/2c9a2f8b1cf44a76b5b73a890bc8f73e

Zobrazit plný text záznamu

NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older Adults

Autor: Riekelt H. Houtkooper, Niels J. Connell, Ciaran E. Fealy, Patrick Schrauwen, R Hageman, Joris Hoeks, Rubén Zapata-Pérez, Bas Havekes, Esther Moonen-Kornips, J Geurts, J. De Vogel, Yvonne M. H. Bruls, Vera B. Schrauwen-Hinderling, Lotte Grevendonk

Publikováno v: Journal of Nutrition, 151(10), 2917-2931. Oxford University Press
Journal of nutrition, 151(10), 2917-2931. American Society for Nutrition
The Journal of Nutrition

Background Boosting NAD+ via supplementation with niacin equivalents has been proposed as a potential modality capable of promoting healthy aging and negating age-dependent declines of skeletal muscle mass and function. Objectives We investigated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aead37e22bb554e94428239aebdbcc15
https://cris.maastrichtuniversity.nl/en/publications/fd3b451c-f271-405a-a9b1-58deca02819d

Zobrazit plný text záznamu

L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility

Autor: Yvo J. M. op den Kamp, Vera B. Schrauwen-Hinderling, Joachim E. Wildberger, Yvonne M. H. Bruls, Patrick Schrauwen, Gert Schaart, Bas Havekes, Lucas Lindeboom, Esther Phielix, Esther Moonen-Kornips, Matthijs K. C. Hesselink

Publikováno v: PLOS ONE, 15(9):0239506. Public Library of Science
PLOS ONE
PLoS ONE, Vol 15, Iss 9, p e0239506 (2020)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7638bcd16383e2e75742234313b2301c
https://cris.maastrichtuniversity.nl/en/publications/c65012b4-8788-4a88-9730-027f39bb0bf0

Zobrazit plný text záznamu

Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liver

Autor: Tomas Jelenik, Anne Gemmink, Matthijs K. C. Hesselink, Bram Brouwers, Patrick Schrauwen, Dennis Dahlmans, Lauren M. Sparks, Bas Havekes, Michael Roden, Yvonne M. H. Bruls, Vera B. Schrauwen-Hinderling

Publikováno v: American Journal of Physiology : Endocrinology and Metabolism, 314(2), E165-E173. American Physiological Society

Exercise training reduces intrahepatic lipid (IHL) content in people with elevated liver fat content. It is unclear, however, whether exercise training reduces IHL content in people with normal liver fat content. Here, we measured the effect of exerc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36d07ea76f30c2582d8f55efe8a04d2
https://cris.maastrichtuniversity.nl/en/publications/b0ee0462-b3c5-40b7-a2a6-5aa34b8d98fc

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání