Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation

Autor: Jennifer Janina Stepanek, Abdulkadir Yayci, Martin Kozik, Niklas B.M. Janzing, Britta Schubert, Martin Benda, Yvonne Märtens, Kenneth C. Keiler, Jared T. Shaw, Lars I. Leichert, Bingyao Zhu, Tadeja Lukežič, Heike Brötz-Oesterhelt, Michaela Wenzel, Jörg Stülke, Maya Penkova, Ümran Ay, Kathi Scheinpflug, John N. Alumasa, Reece G. Miller, Christoph Helmut Rudi Senges, Christian Hertweck, Jean M. Brunel, Helen L. Warmuth, Sina Schäkermann, Julia E. Bandow, Nicole Lorenz, Melissa Vázquez Hernández, Bauke Albada, Nadja Raatschen, Jens Bongard, Nohemy A. Sorto, Pascal Prochnow, Nils Metzler-Nolte, Hrvoje Petković

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2020, 65 (1), pp.e01373-20. ⟨10.1128/AAC.01373-20⟩
Antimicrobial Agents and Chemotherapy, 65(1)
Antimicrobial Agents and Chemotherapy, 2020, 65 (1), pp.e01373-20. ⟨10.1128/AAC.01373-20⟩
Antimicrobial Agents and Chemotherapy 65 (2021) 1
Antimicrobial agents and chemotherapy, vol 65, iss 1

New antibiotics are urgently needed to address the mounting resistance challenge. In early drug discovery, one of the bottlenecks is the elucidation of targets and mechanisms. To accelerate antibiotic research, we provide a proteomic approach for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df45f8b4378fa90f98c46d45bd3b9497
https://doi.org/10.1128/aac.01373-20