Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yvonne Lis"'
Autor:
Malte Juchem, Nele Lehmann, Yvonne Lisa Behrens, Christian Bär, Thomas Thum, Jeannine Hoepfner
Publikováno v:
Stem Cell Research, Vol 79, Iss , Pp 103478- (2024)
The X-linked lysosomal storage disorder Fabry disease originates from GLA gene mutations causing α-galactosidase A enzyme deficiency. Here we generated the GLA knockout hiPSC line MHHi001-A-15 (GLA-KO hiPSC) as an in vitro Fabry disease model by tar
Externí odkaz:
https://doaj.org/article/dc79d98e000645619d1df4b30b25b3e3
Autor:
Christopher Jahn, Malte Juchem, Kristina Sonnenschein, Anika Gietz, Theresa Buchegger, Nico Lachmann, Gudrun Göhring, Yvonne Lisa Behrens, Christian Bär, Thomas Thum, Jeannine Hoepfner
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103404- (2024)
Fabry disease (FD) is a rare and inherited monogenetic disease caused by mutations in the X-chromosomal alpha-galactosidase A gene GLA concomitant with accumulation of its substrate globotriaosylceramide (Gb3) and multi-organ symptoms. We derived an
Externí odkaz:
https://doaj.org/article/3b872bd17b574fc09cc9f159e84b496d
Autor:
Yvonne Lisa Behrens, Gudrun Göhring, Laura Gaschler, Ronny Nienhold, Thea Reinkens, Elke Schirmer, Sabine Lukat, Sabine Knöß, Renate Strasser, Stephanie Sembill, Zofia Wotschofsky, Meinolf Suttorp, Manuela Krumbholz, Brigitte Schlegelberger, Markus Metzler, Axel Karow
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100067- (2023)
Externí odkaz:
https://doaj.org/article/54bcb69c90bd43ab9dc33c418b839f96
Autor:
Lukas Westermann, Yong Li, Burulca Göcmen, Matthias Niedermoser, Kilian Rhein, Johannes Jahn, Isabel Cascante, Felix Schöler, Niklas Moser, Björn Neubauer, Alexis Hofherr, Yvonne Lisa Behrens, Gudrun Göhring, Anna Köttgen, Michael Köttgen, Tilman Busch
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Genome editing tools such as CRISPR/Cas9 enable the rapid and precise manipulation of genomes. CRISPR-based genome editing has greatly simplified the study of gene function in cell lines, but its widespread use has also highlighted challenge
Externí odkaz:
https://doaj.org/article/dfb8393f4f104d318f92b9e9ef18d933
Autor:
Yvonne Lisa Behrens, Laura Gaschler, Ronny Nienhold, Thea Reinkens, Elke Schirmer, Sabine Knöß, Renate Strasser, Stephanie Sembill, Zofia Wotschofsky, Meinolf Suttorp, Manuela Krumbholz, Brigitte Schlegelberger, Markus Metzler, Gudrun Göhring, Axel Karow
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/2991f0a209f34f849c803225ef909f31
Autor:
Rabia Shahswar, Gernot Beutel, Razif Gabdoulline, Adrian Schwarzer, Arnold Kloos, Christian Koenecke, Michael Stadler, Gudrun Gohring, Yvonne Lisa Behrens, Zhixiong Li, Louisa-Kristin Dallmann, Piroska Klement, Catherin Albert, Martin Wichmann, Yasmine Alwie, Axel Benner, Maral Saadati, Arnold Ganser, Felicitas Thol, Michael Heuser
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Treatment options for relapsed and refractory acute myeloid leukemia patients (R/R AML) are limited. This retrospective cohort study compares safety and efficacy of fludarabine, cytarabine, and idarubicin (FLA-IDA) without or with venetoclax (FLAVIDA
Externí odkaz:
https://doaj.org/article/3e7c9d7e6a4f485a890f7508ac5f6304
Publikováno v:
Value in Health. 15:1108-1118
Objective 1) To compare the Food and Drug Administration's (FDA's) Risk Evaluation and Mitigation Strategies (REMS) and European Medicines Agency's (EMA's) Risk Management Plan (RMP) guidances and 2) to compare REMS and RMPs for specific chemical ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc601148dca7495411d27299049e7a9
https://doi.org/10.1016/j.jval.2012.06.019
https://doi.org/10.1016/j.jval.2012.06.019
Autor:
Silke Fähnrich, Hans G. Drexler, Yvonne Lis, Roderick A.F. MacLeod, Elisabeth Becker, W. G. Dirks
Publikováno v:
International Journal of Cancer. 100:49-56
The initial identification of the ALK gene, expressed as C-terminal part of the transforming fusion protein NPM-ALK in the t(2;5)(p23;q35) lymphoma-associated chromosomal translocation, revealed a novel receptor tyrosine kinase (RTK). In order to exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3cf5adc14358ce17a8b3ddd387f774
https://doi.org/10.1002/ijc.10435
https://doi.org/10.1002/ijc.10435
Publikováno v:
Journal of Clinical Epidemiology. 47:307-312
The initial results are reported of a case-control study undertaken on the VAMP multi-purpose database and designed to estimate the risk for first-time occurrence of myocardial infarction in users of hormone replacement therapy (HRT). The findings cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1d1f92828e9d077f4d9769e16b5c35
https://doi.org/10.1016/0895-4356(94)90014-0
https://doi.org/10.1016/0895-4356(94)90014-0
Publikováno v:
Value in Health. 14(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43436a0f9052593c50a8fe2abd52d002