Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yvonne L. Chao"'
Autor:
Patrick L. Leslie, Yvonne L. Chao, Yi-Hsuan Tsai, Subrata K. Ghosh, Alessandro Porrello, Amanda E. D. Van Swearingen, Emily B. Harrison, Brian C. Cooley, Joel S. Parker, Lisa A. Carey, Chad V. Pecot
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The prognosis of cancer patients with lymph node (LN) metastasis is worse than those without. Here, the authors report that while histone deacetylase 11 (HDAC11) inhibition suppresses tumor growth within the LN, it also promotes cancer cell migration
Externí odkaz:
https://doaj.org/article/8e3b52eb05f3442ca4bd8694e416db75
Autor:
Alessandro Porrello, Patrick L. Leslie, Emily B. Harrison, Balachandra K. Gorentla, Sravya Kattula, Subrata K. Ghosh, Salma H. Azam, Alisha Holtzhausen, Yvonne L. Chao, Michele C. Hayward, Trent A. Waugh, Sanggyu Bae, Virginia Godfrey, Scott H. Randell, Cecilia Oderup, Liza Makowski, Jared Weiss, Matthew D. Wilkerson, D. Neil Hayes, H. Shelton Earp, Albert S. Baldwin, Alisa S. Wolberg, Chad V. Pecot
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Lung squamous carcinomas (LUSC) are poorly molecularly characterized, but sub-populations show promising response to immune checkpoint inhibitors. Here, the authors identify a subset of LUSC characterized by infiltration of inflammatory monocytes, wh
Externí odkaz:
https://doaj.org/article/98a06355bdd34530b4587e1a8b9d1ffe
Autor:
Lisa A. Carey, Patrick L. Leslie, Yvonne L. Chao, Alessandro Porrello, Yi-Hsuan Tsai, Emily B. Harrison, Joel S. Parker, Subrata K. Ghosh, Brian C. Cooley, Chad V. Pecot, Amanda E.D. Van Swearingen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Lymph node (LN) metastases correspond with a worse prognosis in nearly all cancers, yet the occurrence of cancer spreading from LNs remains controversial. Additionally, the mechanisms explaining how cancers survive and exit LNs are largely unknown. H
Autor:
Balachandra K. Gorentla, Patrick L. Leslie, Trent A. Waugh, D. Neil Hayes, Jared Weiss, Albert S. Baldwin, Emily B. Harrison, Subrata K. Ghosh, Alessandro Porrello, Yvonne L. Chao, Michele C. Hayward, Alisa S. Wolberg, Sravya Kattula, Alisha Holtzhausen, Matthew D. Wilkerson, Cecilia Oderup, Chad V. Pecot, Liza Makowski, Virginia Godfrey, Sanggyu Bae, Scott H. Randell, H. Shelton Earp, Salma H. Azam
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Nature Communications
Nature Communications
Lung cancer is the leading cause of cancer-related deaths worldwide, and lung squamous carcinomas (LUSC) represent about 30% of cases. Molecular aberrations in lung adenocarcinomas have allowed for effective targeted treatments, but corresponding the
Autor:
Carey K. Anders, Yvonne L. Chao
Publikováno v:
Current Breast Cancer Reports. 9:217-226
Over 25% of patients with metastatic breast cancer will develop brain metastases. Recent advances in systemic therapy, especially molecularly targeted agents, have improved control of extracranial disease, but have had limited effect on intracranial
Autor:
Yinzhou Zhu, Yi-Hsuan Tsai, Chad V. Pecot, Yvonne L. Chao, Lisa A. Carey, Jimena Giudice, Amanda E.D. Van Swearingen, Lily Wilkinson, Christopher L. Holley, Alessandro Porrello, Hannah J. Wiedner
Publikováno v:
Cancer Research. 81:PD15-01
Background: While the presence of lymph node (LN) metastases in solid tumor malignancies is clinically significant and associated with increased risk for distant metastases, there is little evidence that lymphatic metastasis is distinct from hematoge
Autor:
Chad V. Pecot, Yvonne L. Chao
Publikováno v:
Cold Spring Harb Perspect Med
The epigenetic landscape, which in part includes DNA methylation, chromatin organization, histone modifications, and noncoding RNA regulation, greatly contributes to the heterogeneity that makes developing effective therapies for lung cancer challeng
Autor:
Yvonne L. Chao, Chad V. Pecot
Publikováno v:
Immunotherapy. 10(8)
Autor:
Carey K. Anders, Yvonne L. Chao
Publikováno v:
Clinical breast cancer. 18(3)
Autor:
Kathleen M. Munson, Randall T. Peterson, Calum A. MacRae, Jing-Ruey J. Yeh, Yvonne L. Chao, Quinn P. Peterson
Publikováno v:
Development. 135:401-410
AML1-ETO is one of the most common chromosomal translocation products associated with acute myelogenous leukemia (AML). Patients carrying the AML1-ETO fusion gene exhibit an accumulation of granulocyte precursors in the bone marrow and the blood. Her