Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Yvonne K. Gruijthuijsen"'
1
Helix 8 of the viral chemokine receptor ORF74 directs chemokine binding
Autor: Mario Schwarz, Philip M. Murphy, Yvonne K. Gruijthuijsen, Marie van Dijk, Dennis Verzijl, John Nicholas, Henk Timmerman, Leonardo Pardo, Martine J. Smit, Aldo Jongejan, Rob Leurs
Publikováno v: Verzijl, D, Pardo, L M, van Dijk, M A, Gruijthuijsen, Y K, Jongejan, A, Timmerman, H, Nicholas, J, Schwarz, M, Murphy, P M, Leurs, R & Smit, M J 2006, ' Helix 8 of the viral chemokine receptor ORF74 directs chemokine binding ', Journal of Biological Chemistry, vol. 281, no. 46, pp. 35327-35 . https://doi.org/10.1074/jbc.M606877200
Journal of Biological Chemistry, 281(46), 35327-35. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 281(46), 35327-35335. American Society for Biochemistry and Molecular Biology Inc.
Verzijl, D, Pardo, L, Van Dijk, M, Gruijthuijsen, Y K, Jongejan, A, Timmerman, H, Nicholas, J, Schwarz, M, Murphy, P M, Leurs, R & Smit, M J 2006, ' Helix 8 of the viral chemokine receptor ORF74 directs chemokine binding ', Journal of Biological Chemistry, vol. 281, no. 46, pp. 35327-35335 . https://doi.org/10.1074/jbc.M606877200
The constitutively active G-protein-coupled receptor and viral oncogene ORF74, encoded by Kaposi sarcoma-associated herpesvirus (human herpesvirus 8), binds a broad range of chemokines, including CXCL1 (agonist), CXCL8 (neutral ligand), and CXCL10 (i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3108a879ff28de07fe9512843823ae
https://doi.org/10.1074/jbc.m606877200
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2
The Epstein-Barr Virus BILF1 Gene Encodes a G Protein-Coupled Receptor That Inhibits Phosphorylation of RNA-Dependent Protein Kinase
Autor: Dennis Verzijl, Martine J. Smit, Cathrien A. Bruggeman, Erik Beuken, Patrick S. Beisser, Cornelis Vink, Rob Leurs, Yvonne K. Gruijthuijsen
Publikováno v: Beisser, P S, Verzijl, D, Gruijthuijsen, Y K, Beuken, E V, Smit, M J, Leurs, R, Bruggeman, C A & Vink, C 2005, ' The Epstein-Barr virus BILF1 gene encodes a G protein-coupled receptor that inhibits phosphorylation of RNA-dependent protein kinase ', Journal of Virology, vol. 79, no. 1, pp. 441-9 . https://doi.org/10.1128/JVI.79.1.441-449.2005
Journal of Virology, 79(1), 441-9. American Society for Microbiology
Epstein-Barr virus (EBV) infection is associated with many lymphoproliferative diseases, such as infectious mononucleosis and Burkitt's lymphoma. Consequently, EBV is one of the most extensively studied herpesviruses. Surprisingly, a putative G prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727a7c5ca20b8c7a83d8d41025b9896c
https://doi.org/10.1128/jvi.79.1.441-449.2005
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3
Mutational analysis of the R33-encoded G protein-coupled receptor of rat cytomegalovirus: identification of amino acid residues critical for cellular localization and ligand-independent signalling
Autor: Erik Beuken, Martine J. Smit, Cathrien A. Bruggeman, Rob Leurs, Cornelis Vink, Yvonne K. Gruijthuijsen
Publikováno v: Journal of General Virology, 85(Pt 4), 897-909. Society for General Microbiology
Gruijthuijsen, Y K, Beuken, E V, Smit, M J, Leurs, R, Bruggeman, C A & Vink, C 2004, ' Mutational analysis of the R33-encoded G protein-coupled receptor of rat cytomegalovirus: identification of amino acid residues critical for cellular localization and ligand-independent signalling ', Journal of General Virology, vol. 85, no. Pt 4, pp. 897-909 . https://doi.org/10.1099/vir.0.19709-0
The rat cytomegalovirus (RCMV)R33gene encodes a G protein-coupled receptor (GPCR), pR33, which possesses agonist-independent, constitutive signalling activity. To characterize this activity further, we generated a series of point and deletion mutants
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f36ef7a598aa4ab40abd4a06d9e8d0
https://doi.org/10.1099/vir.0.19709-0
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4
The rat cytomegalovirus R78 G protein-coupled receptor gene is required for production of infectious virus in the spleen
Autor: Gert Grauls, Suzanne J.F. Kaptein, Cathrien A. Bruggeman, Patrick S. Beisser, Koen W. R. van Cleef, Yvonne K. Gruijthuijsen, Kim G.M. Savelkouls, Cornelis Vink, Erik Beuken
Publikováno v: Journal of General Virology. 84:2517-2530
The rat cytomegalovirus (RCMV) R33 and R78 genes are conserved within members of the subfamily Betaherpesvirinae and encode proteins (pR33 and pR78, respectively) that show sequence similarity with G protein-coupled receptors. Previously, the biologi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6bce0d14195c3b79b70020256c6235
https://doi.org/10.1099/vir.0.19227-0
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5
The r131 gene of rat cytomegalovirus encodes a proinflammatory CC chemokine homolog which is essential for the production of infectious virus in the salivary glands
Autor: Cornelis Vink, Frank R. M. Stassen, Cathrien A. Bruggeman, Patrick S. Beisser, Lieve van Buggenhout, Yvonne K. Gruijthuijsen, Erik Beuken, Suzanne J.F. Kaptein, Koen W. R. van Cleef
Publikováno v: Virus genes. 29(1)
Rat cytomegalovirus (RCMV) possesses two adjacent genes, r131 and r129, which have the potential to encode CC chemokine homologs. Interestingly, the amino acid sequences encoded by both genes show similarity to the sequence of the murine CMV (MCMV) M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd6bc131989c25c0bde3c9598460054
https://pubmed.ncbi.nlm.nih.gov/15215683
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6
Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes
Autor: Rob Leurs, Martine J. Smit, Thomas Mertens, Paola Casarosa, Detlef Michel, Patrick S. Beisser, Cornelis Vink, Cathrien A. Bruggeman, Dennis Verzijl, Carlos P. Fitzsimons, Jens Holl, Yvonne K. Gruijthuijsen
Publikováno v: Journal of Biological Chemistry, 278(50), 50010-23. American Society for Biochemistry and Molecular Biology Inc.
Casarosa, P, Gruijthuijsen, Y K, Michel, D, Beisser, P S, Holl, J, Fitzsimons, C P, Verzijl, D, Bruggeman, C A, Mertens, T, Leurs, R, Vink, C & Smit, M J 2003, ' Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes ', Journal of Biological Chemistry, vol. 278, no. 50, pp. 50010-23 . https://doi.org/10.1074/jbc.M306530200
The human cytomegalovirus (HCMV) UL33 gene is conserved among all beta-herpesviruses and encodes a protein that shows sequence similarity with chemokine receptors belonging to the family of G protein-coupled receptors. Here, we show that HCMV UL33 is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d340c763beaa7f4205c25ddb987574
https://research.vu.nl/en/publications/04b3c885-2094-415a-a458-eb7a7b7d7157
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7
The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion
Autor: Cornelis Vink, Suzanne J.F. Kaptein, Jos L. V. Broers, Martine J. Smit, Cathrien A. Bruggeman, Rob Leurs, Paola Casarosa, Yvonne K. Gruijthuijsen
Publikováno v: Journal of virology, 76(3), 1328-1338. American Society for Microbiology
Journal of Virology, 76(3), 1328-38. American Society for Microbiology
Gruijthuijsen, Y K, Casarosa, P, Kaptein, S J, Broers, J L, Leurs, R, Bruggeman, C A, Smit, M J & Vink, C 2002, ' The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion ', Journal of Virology, vol. 76, no. 3, pp. 1328-38 . https://doi.org/10.1128/JVI.76.3.1328-1338.2002
The rat cytomegalovirus (RCMV) R33 gene is conserved among all betaherpesviruses and encodes a protein (pR33) that shows sequence similarity with chemokine-binding G protein-coupled receptors (GPCRs). Previously, the physiological significance of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179518c5d07ff3a4baaa63a0c347b659
https://research.tue.nl/nl/publications/bbe9f23a-7b77-44d5-b1a6-d8fd9c9b3c38
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8
Rat cytomegalovirus R89 is a highly conserved gene which expresses a spliced transcript
Autor: Yvonne K. Gruijthuijsen, Cathrien A. Bruggeman, Erik Beuken, Cornelis Vink
Publikováno v: Virus research. 69(2)
In all sequenced herpesvirus genomes, a homolog of the herpes simplex virus type 1 UL15 gene has been identified. This gene encodes a protein that is involved in viral genome maturation. Although transcription of the alphaherpesvirus UL15 gene has be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23fa28ff7302f78e49afabbab80716d
https://pubmed.ncbi.nlm.nih.gov/11018281
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