Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer's disease

Autor: Yolande A.L. Pijnenburg, Philip Scheltens, Wiesje M. van der Flier, Iris E. Jansen, Martine J. van Belzen, Merel W. Boogaard, Jacobijn Gussekloo, Stella Trompet, Raymund A.C. Roos, Yvonne J.M. Campman, N. Ahmad Aziz, Aster V.E. Harder, Sarah L. Gardiner

Publikováno v: Neurobiology of Aging, 73, 230.e9-230.e17. Elsevier Inc.
Neurobiology of aging 73, 230.e9-230.e17 (2019). doi:10.1016/j.neurobiolaging.2018.09.007
Neurobiology of Aging, 73
Gardiner, S L, Harder, A V E, Campman, Y J M, Trompet, S, Gussekloo, J, van Belzen, M J, Boogaard, M W, Roos, R A C, Jansen, I E, Pijnenburg, Y A L, Scheltens, P, van der Flier, W M & Aziz, N A 2019, ' Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer's disease ', Neurobiology of Aging, vol. 73, pp. 230.e9-230.e17 . https://doi.org/10.1016/j.neurobiolaging.2018.09.007

Genomewide association studies (GWASs) have contributed greatly to unraveling the genetic basis of Alzheimer's disease (AD). However, a large amount of “missing heritability” remains. In this exploratory study, we investigated the effect of cytos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a44af72365ba7bf897e11cefc146843
https://hdl.handle.net/1887/116663