Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yvonne J, Hort"'
Autor:
Andrew Mallett, Mark J. Cowley, Michel Tchan, Sarah R. Senum, Gopala K. Rangan, André E. Minoche, Amali Mallawaarachchi, Timothy J. Furlong, Ben Lundie, John Shine, Peter C. Harris, Marcel E. Dinger, Georgina E Hollway, Velimir Gayevskiy, Marcus Hinchcliffe, Leslie Burnett, Thomas Ohnesorg, Yvonne J. Hort, Nicole Schonrock, Chirag Patel
Publikováno v:
Eur J Hum Genet
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is common, with a prevalence of 1/1000 and predominantly caused by disease-causing variants in PKD1 or PKD2. Clinical diagnosis is usually by age-dependent imaging criteria, which is challenging in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01560009049474c33ee21f7ddd6a90b
https://doi.org/10.1038/s41431-020-00796-4
https://doi.org/10.1038/s41431-020-00796-4
Autor:
Yvonne J. Hort, Günther Sperk, Ramon O. Tasan, Kharen L. Doyle, John Shine, Herbert Herzog, Carla Cunha
Publikováno v:
Neuropeptides. 68:90-98
The mouse olfactory neuroepithelium (ON) is comprised of anatomically distinct populations of cells in separate regions; apical (sustentacular and microvillar), neuronal (olfactory sensory neurons) and basal (horizontal and globose basal cells). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4478dfec2f40580bd45d8605749ab2cb
https://doi.org/10.1016/j.npep.2018.02.007
https://doi.org/10.1016/j.npep.2018.02.007
Autor:
Yvonne J. Hort, Timothy J. Furlong, Marcel E. Dinger, Mark J. Cowley, Mark J. McCabe, John Shine, André E. Minoche, Amali Mallawaarachchi
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disorder and is due to disease-causing variants in PKD1 or PKD2. Strong genotype-phenotype correlation exists although diagnostic sequencing is not part of routi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9dc49e7e278465cc4963ba7857acfc
https://europepmc.org/articles/PMC5110048/
https://europepmc.org/articles/PMC5110048/
Publikováno v:
Journal of Neuroscience Research. 90:1126-1135
Neuropeptide Y (NPY) and peptide YY (PYY) are differentially expressed throughout the olfactory neuroepithelium (ON), with NPY expression present in sustentacular cells, olfactory ensheathing cells, and olfactory receptor neurons and PYY expressed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a9a1b88ca7ab8bdc561972ea9aa0b2
https://doi.org/10.1002/jnr.23008
https://doi.org/10.1002/jnr.23008
Publikováno v:
Journal of Neurochemistry. 105:641-652
While the regenerative capacity of the olfactory neuroepithelium has been well studied less is known about the molecular events controlling precursor cell activity. Neuropeptide Y (NPY) is expressed at high levels in the olfactory system, and NPY has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d8fd71769cb8e16e4706eeb0778f40
https://doi.org/10.1111/j.1471-4159.2007.05188.x
https://doi.org/10.1111/j.1471-4159.2007.05188.x
Publikováno v:
Molecular Brain Research. 107:195-200
The GALR1 galanin receptor is expressed at high levels within the central nervous system. To determine which specific actions of galanin are mediated by GALR1, we have developed mice with an insertional inactivating mutation within the gene encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd257986e9fdee7755f7b205a719c4e4
https://doi.org/10.1016/s0169-328x(02)00451-5
https://doi.org/10.1016/s0169-328x(02)00451-5
Autor:
Kin-Chuen Leung, Tiina P. Lismaa, Jennifer Turner, Ken K. Y. Ho, John P. Sheehy, Yvonne J. Hort, Betty Leung
Publikováno v:
Clinical Endocrinology. 56:397-403
Summary objectives Galanin (GAL) is a neuropeptide widely expressed in the central and peripheral nervous system and in neuroendocrine tissue, including the adenohypophysis where, in humans, it is expressed in corticotrophs and in ACTH-producing aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c55f07f468bb688c3d9f1682d10fdd7
https://doi.org/10.1046/j.1365-2265.2002.01486.x
https://doi.org/10.1046/j.1365-2265.2002.01486.x
Publikováno v:
Letters in Peptide Science. 8:139-146
The GALR1 galanin receptor is expressed at high levels within the central nervous system and is hypothesised to play a significant role in many of the central actions of galanin. To determine which specific actions of galanin are mediated by GALR1, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5641c6158283a3083f89b21c3677f91
https://doi.org/10.1007/bf02446510
https://doi.org/10.1007/bf02446510
Publikováno v:
Genome Research. 6:858-861
The human retinoblastoma susceptibility gene, a member of the tumor suppressor gene family, is located on chromosome 13q14.12-13q14.2 and consists of 27 exons that are distributed over 180 kb. This study shows that intron 17, the largest in size, con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a589b32fa6d53331058eace1cf29bfa
https://doi.org/10.1101/gr.6.9.858
https://doi.org/10.1101/gr.6.9.858
Publikováno v:
Genomics. 32:484-486
This report describes the localization of a novel human focal adhesion kinase, FAK2, to human chromosome 8p11.2-p22 using in situ hybridization. The focal adhesion kinases are a subfamily of protein tyrosine kinases and aid in the transduction of lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e869674e5aefa0fbde07c64800d775c
https://doi.org/10.1006/geno.1996.0149
https://doi.org/10.1006/geno.1996.0149