Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yvonne Hari"'
Autor:
Paulius Ruzgys, Stephan Böhringer, Ayse Sila Dokumaci, Yvonne Hari, Christian M. Schürch, Frido Brühl, Stefan Schürch, Sönke Szidat, Carsten Riether, Saulius Šatkauskas, Thomas Geiser, David Hradetzky, Amiq Gazdhar
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: An advanced stage, centrally localized invasive tumor is a major cause of sudden death in lung cancer patients. Currently, chemotherapy, radiotherapy, laser ablation, or surgical resection if possible are the available state-of-the-art tr
Externí odkaz:
https://doaj.org/article/33c12e6764224a9c9a414c5ba0cf11b9
Publikováno v:
CHIMIA, Vol 71, Iss 3 (2017)
The search for effective drugs against cisplatin-resistant tumors resulted in a large number of organometallic compounds that are evaluated for their antiproliferative activity. Among the most promising candidates are bent metallocenes based on vario
Externí odkaz:
https://doaj.org/article/af1698057e0a443a9839cdfb69f3a592
Publikováno v:
CHIMIA, Vol 68, Iss 3 (2014)
In continuation of the long tradition of mass spectrometric research at the University of Bern, our group focuses on the characterization of nucleic acids as therapeutic agents and as drug targets. This article provides a short overview of our recent
Externí odkaz:
https://doaj.org/article/b98423fe214d486c85c2828586a221e3
Autor:
Yvonne Hari, Silvan R. Stucki, Adrien Nyakas, Lorenz Blum, Jean-Louis Reymond, Stefan Schürch
Publikováno v:
CHIMIA, Vol 68, Iss 1-2 (2014)
Externí odkaz:
https://doaj.org/article/bd2d8b9d0c12435c8d9c9b910f44195e
Autor:
Alena Istrate, Branislav Dugovic, Stefan Schürch, Christian J. Leumann, Annabel Fignolé, Yvonne Hari
Publikováno v:
Journal of the American Society for Mass Spectrometry. 27:1186-1196
Tricyclo-DNA (tcDNA) is a sugar-modified analogue of DNA currently tested for the treatment of Duchenne muscular dystrophy in an antisense approach. Tandem mass spectrometry plays a key role in modern medical diagnostics and has become a widespread t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a14cb3e84829534f2c9995725c7330
https://doi.org/10.1007/s13361-016-1391-3
https://doi.org/10.1007/s13361-016-1391-3
Autor:
Yvonne, Hari, Silvan R, Stucki, Adrien, Nyakas, Lorenz, Blum, Jean-Louis, Reymond, Stefan, Schürch
Publikováno v:
Chimia. 68(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5ed1418942cc726b09e07cb635cc641
https://pubmed.ncbi.nlm.nih.gov/28982446
https://pubmed.ncbi.nlm.nih.gov/28982446
Publikováno v:
Journal of the American Society for Mass Spectrometry. 28(12)
Radical activation methods, such as electron transfer dissociation (ETD), produce structural information complementary to collision-induced dissociation. Herein, electron transfer dissociation of 3-fold protonated DNA hexamers was studied to gain ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649e8b2eef46a5f0d38908da44b54581
https://pubmed.ncbi.nlm.nih.gov/28932996
https://pubmed.ncbi.nlm.nih.gov/28932996
Publikováno v:
Eberle, RahelP.; Hari, Yvonne Ilona; Schürch, Stefan (2017). Transition Metal-based Anticancer Drugs Targeting Nucleic Acids: A Tandem Mass Spectrometric Investigation. CHIMIA, 71(3), pp. 120-123. Schweizerische Chemische Gesellschaft 10.2533/chimia.2017.120
CHIMIA, Vol 71, Iss 3 (2017)
Chimia
CHIMIA, Vol 71, Iss 3 (2017)
Chimia
The search for effective drugs against cisplatin-resistant tumors resulted in a large number of organometallic compounds that are evaluated for their antiproliferative activity. Among the most promising candidates are bent metallocenes based on vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63594fe949d20a5fa48c293a19bce401
Publikováno v:
J. Am. Soc. Mass Spectrom.
Bent metallocenes Cp2MCl2 (M = Ti, V, Nb, Mo) are known to exhibit cytotoxic activity against a variety of cancer types. Though the mechanism of action is not fully understood yet, the accumulation of the metal ions in the nucleus points towards DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecd2c64eb6e2dfe82064e0388d4a246
https://pubmed.ncbi.nlm.nih.gov/28500584
https://pubmed.ncbi.nlm.nih.gov/28500584
Autor:
Volker Auwärter, Stefan König, Alexandra Schröck, Yvonne Hari, Stefan Schürch, Wolfgang Weinmann
Publikováno v:
Drug Testing and Analysis. 6:363-366
During the last few years γ-hydroxybutyric acid (GHB) and γ-butyrolactone (GBL) have attracted much interest as recreational drugs and knock-out drops in drug-facilitated sexual assaults. This experiment aims at getting an insight into the pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f6e778dd9c93cf03fca8616e043c51
https://doi.org/10.1002/dta.1498
https://doi.org/10.1002/dta.1498