Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yvonne G. Y. Chan"'
Autor:
Swati Gupta, Leena McCann, Yvonne G. Y. Chan, Edwin W. Lai, Wei Wei, Pok Fai Wong, James W. Smithy, Jodi Weidler, Brian Rhees, Michael Bates, Harriet M. Kluger, David L. Rimm
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract Background In melanoma, there is no companion diagnostic test to predict response to programmed cell death 1 (PD-1) axis immune checkpoint inhibitor (ICI) therapy. In the adjuvant setting, only one in five patients may benefit from ICI, so a
Externí odkaz:
https://doaj.org/article/753f2d78f9e54da6aa048a1cde53fbc9
Publikováno v:
Journal of Biological Chemistry. 289:15680-15690
Envelope biogenesis in bacteria involves synthesis of intermediates that are tethered to the lipid carrier undecaprenol-phosphate. LytR-CpsA-Psr (LCP) enzymes have been proposed to catalyze the transfer of undecaprenol-linked intermediates onto the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1c8069e3022baa1bc4e0e6e9019002
https://doi.org/10.1074/jbc.m114.567669
https://doi.org/10.1074/jbc.m114.567669
Autor:
Swati Gupta, Pok Fai Wong, Harriet M. Kluger, Edwin W. Lai, Brian Rhees, David L. Rimm, Leena McCann, Michael Bates, Jodi Weidler, Yvonne G. Y. Chan, James W. Smithy
Publikováno v:
Cancer Research. 79:3142-3142
Background: In melanoma, there is no companion diagnostic test to predict response to programmed cell death 1 (PD-1) axis immune checkpoint inhibitor therapy (ICI). In the adjuvant setting, only 1 in 5 patients may benefit from ICI, so biomarker is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26df88a0f4e533b01ef3639a27ac8b9b
https://doi.org/10.1158/1538-7445.am2019-3142
https://doi.org/10.1158/1538-7445.am2019-3142
The envelope of Staphylococcus aureus is comprised of peptidoglycan and its attached secondary polymers, teichoic acid, capsular polysaccharide, and protein. Peptidoglycan synthesis involves polymerization of lipid II precursors into glycan strands t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd98707ef1af35a38bea56f00c0394e
https://europepmc.org/articles/PMC4800868/
https://europepmc.org/articles/PMC4800868/
Autor:
Timothy M. Hermanas, Kenneth C. Goh, Sean P. Riley, Juan J. Martinez, Yvonne G. Y. Chan, Marissa M. Cardwell
Publikováno v:
Infection and Immunity. 78:1895-1904
The pathogenesis of spotted fever group (SFG)Rickettsiaspecies, includingR. conoriiandR. rickettsii, is acutely dependent on adherence to and invasion of host cells, including cells of the mammalian endothelial system. Bioinformatic analyses of sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebb61a65d920a49c59a6275df7731ae
https://doi.org/10.1128/iai.01165-09
https://doi.org/10.1128/iai.01165-09
Autor:
Timothy M. Hermanas, Yvonne G. Y. Chan, Juan J. Martinez, Tsuneo Uchiyama, Marissa M. Cardwell
Publikováno v:
Cellular Microbiology. 11:629-644
Rickettsia conorii, an obligate intracellular tick-borne pathogen and the causative agent of Mediterranean spotted fever, binds to and invades non-phagocytic mammalian cells. Previous work identified Ku70 as a mammalian receptor involved in the invas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913c572944a0ca5312de8b67c5e91065
https://doi.org/10.1111/j.1462-5822.2008.01279.x
https://doi.org/10.1111/j.1462-5822.2008.01279.x
Autor:
Olaf Schneewind, Yvonne G. Y. Chan, J. M. Lunderberg, Dominique Missiakas, Megan Liszewski Zilla
Publikováno v:
Journal of bacteriology. 197(2)
Bacillus anthracis, the causative agent of anthrax, replicates as chains of vegetative cells by regulating the separation of septal peptidoglycan. Surface (S)-layer proteins and associated proteins (BSLs) function as chain length determinants and bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3297445fd901f173df1a390e5eb74b3
https://pubmed.ncbi.nlm.nih.gov/25384480
https://pubmed.ncbi.nlm.nih.gov/25384480
Publikováno v:
Journal of bacteriology. 195(20)
The LytR-CpsA-Psr (LCP) proteins are thought to transfer bactoprenol-linked biosynthetic intermediates of wall teichoic acid (WTA) to the peptidoglycan of Gram-positive bacteria. In Bacillus subtilis , mutants lacking all three LCP enzymes do not dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be1d04f57be0e0998fee8ef4cb89cdd
https://pubmed.ncbi.nlm.nih.gov/23935043
https://pubmed.ncbi.nlm.nih.gov/23935043
Pathogenic rickettsiae are the causative agents of Rocky Mountain spotted fever, typhus, and other human diseases with high mortality and an important impact on society. Although survivors of rickettsial infections are considered immune to disease, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cc0ca23c540cc7cc0b7477b9c41e0e
https://europepmc.org/articles/PMC3125829/
https://europepmc.org/articles/PMC3125829/
Publikováno v:
Frontiers in Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 1 (2010)
Frontiers in Cellular and Infection Microbiology, Vol 1 (2010)
The pathogenic lifecycle of obligate intracellular bacteria presents a superb opportunity to develop understanding of the interaction between the bacteria and host under the pretext that disruption of these processes will likely lead to death of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbb204e3e73ca0667d20830d3b2f8e8
http://europepmc.org/articles/PMC3109342
http://europepmc.org/articles/PMC3109342