Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yvonne G. Lukes"'
Autor:
Catherine A. Dinauer, Yvonne G. Lukes, Gary L. Francis, R. Michael Tuttle, Cydney Fenton, Diarmuid Nicholson
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:1170-1175
The ret/PTC rearrangements (PTC-1, PTC-2, and PTC-3) are characteristic of papillary thyroid cancer (PTC). In adults, PTC-1 is common and may be associated with an aggressive clinical course. The incidence and significance of ret/PTC mutations are le
Autor:
M. Mengistu, Sabita Lahiri, Frances E. Carr, Henry B. Burch, Endre Nagy, Yvonne G. Lukes, Kenneth D. Burman
Publikováno v:
Journal of Endocrinological Investigation. 17:437-441
RNA was isolated from fibroblasts from the retroocular area, from endomysial fibroblasts obtained from orbital lateral rectus muscle, and from abdominal skin fibroblasts. The RNA was reverse transcribed into cDNA which was then used as a template for
Autor:
Yvonne G. Lukes, Frances E. Carr, Thomas B. Francis, Mark E. Peele, Kenneth D. Burman, Henry B. Burch, Wen-Yi Cai, Leonard Wartofsky
Publikováno v:
Thyroid. 1:223-228
Human lymphocytes are known to play a critical role in autoimmune diseases both by producing antibodies and by participating in lymphokine-cellular interactions. TSH, a classic pituitary hormone, may be secreted by human lymphocytes, and controversy
Autor:
Yvonne G. Lukes, Barbara L. Solomon, Gary L. Francis, Cydney Fenton, Aneeta Patel, Jefferey S. Anderson, R. Michael Tuttle, Matthew D. Ringel
Publikováno v:
Pediatric research. 49(3)
Reverse transcriptase-PCR has identified thyroglobulin mRNA (Tg mRNA) in peripheral blood of normal adults and adults with thyroid cancer. However, no children were studied. The primary objective of this study was to determine whether whole blood Tg
Autor:
R M Tuttle, Yvonne G. Lukes, Catherine A. Dinauer, Gary L. Francis, Cydney Fenton, J. Anderson
Publikováno v:
Journal of endocrinological investigation. 22(10)
Mutations in the ras genes (H-ras, K-ras, and N-ras) occur in 10-15% of all human cancers, and commonly arise from single base substitutions at codons 12, 13, or 61. Although ras mutations have been found in adult thyroid cancers, they were absent fr
Autor:
Leonard D. Kohn, Yvonne G. Lukes, S. Kosugi, Kenneth D. Burman, Henry B. Burch, Endre Nagy, Frances E. Carr
Publikováno v:
Journal of endocrinological investigation. 16(7)
Clarifying the role of the TSH receptor protein in the autoimmune process may be the key to understanding the development of Graves’ disease. In the present study we used a 16 amino acid peptide of the human TSH receptor (hTSHR) to immunize rabbits
Autor:
Jesse Greer, Yvonne G. Lukes, Susan Barnes, Jacob F. Collen, Aaron B. Holley, Elena Morris, Christopher J. Lettieri
Publikováno v:
Chest. 138:244A
Autor:
Frances Carr, Yvonne G. Lukes, Kenneth D. Burman, Yin Ying Djuh, Juan D'avis, Phyllis Rhooms, Leonard Wartofsky, Wen Yi Cai, James R. Baker, Henry B. Burch
Publikováno v:
Autoimmunity. 13(1)
Human TSH receptor (hTSH-R) gene and RNA transcripts were analyzed by Southern and Northern blots in patients with various thyroid disorders, and in tissue cell lines. A 1.4 Kb cDNA encoding the extracellular human TSH-R domain was used as a probe. S
Autor:
Kenneth D. Burman, Yvonne G. Lukes, Karen Mahoney, John C. Morris, Endre Nagy, Henry B. Burch
Twenty-nine peptides covering the full extracellular domain of the human thyrotropin receptor have been synthesized and tested for reactivity with Graves' patients' and normal sera in ELISA. Two peptides, amino acids 331–350 and the second extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03834cefd00feae5f2e46506f3da2713
Autor:
Wen Yi Cai, Yvonne G. Lukes, Kenneth D. Burman, Leonard Wartofsky, Endre Nagy, Henry B. Burch
A comparison of the nucleotide sequence of the human thyrotropin receptor (hTSH-R) with that of HIV-1 revealed 61% homology between a 161 base pair region encoding a unique portion of the hTSH-R and an immunogenic HIV-1 regulatory protein, nef. Amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12eaeac861f9eb87e7779081cf43a359