Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Yvonne Freund Levi"'
Autor:
Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Clint De Nolf, Betty M. Tijms, Charlotte E. Teunissen, Suzanne E. Schindler, Frans Verhey, Inez Ramakers, Pablo Martinez-Lage, Mikel Tainta, Rik Vandenberghe, Jolien Schaeverbeke, Sebastiaan Engelborghs, Ellen De Roeck, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Yvonne Freund-Levi, Simon Lovestone, Johannes Streffer, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Pieter Jelle Visser, Roosmarijn E. Vandenbroucke, Stephanie J. B. Vos
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Structural and functional changes of the choroid plexus (ChP) have been reported in Alzheimer’s disease (AD). Nonetheless, the role of the ChP in the pathogenesis of AD remains largely unknown. We aim to unravel the relation bet
Externí odkaz:
https://doaj.org/article/7c5db71c472645af80c01089faaa997c
Autor:
Pieter Jelle Visser, Lianne M. Reus, Johan Gobom, Iris Jansen, Ellen Dicks, Sven J. van der Lee, Magda Tsolaki, Frans R. J. Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, José Luís Molinuevo, Sebastiaan Engelborghs, Yvonne Freund-Levi, Lutz Froelich, Kristel Sleegers, Valerija Dobricic, Simon Lovestone, Johannes Streffer, Stephanie J. B. Vos, Isabelle Bos, ADNI, August B. Smit, Kaj Blennow, Philip Scheltens, Charlotte E. Teunissen, Lars Bertram, Henrik Zetterberg, Betty M. Tijms
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-16 (2022)
Abstract Background Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of Alzheimer’s disease (AD) and is considered to result from neurodegeneration. T-tau levels, however, can be increased in very early disease stage
Externí odkaz:
https://doaj.org/article/4927a15981844155bce3ce2b9e6f5832
Autor:
Hans Westergren, Björn Gerdle, Eva Kosek, Britt-Marie Stålnacke, Paulin Andréll, Rolf Karlsten, Monika Lofgren, Bijar Ghafouri, Malin Ernberg, Emmanuel Bäckryd, Marcelo Rivano Fisher, Yvonne Freund-Levi, Henrik Grelz, Olaf Gräbel, Åsa Ringqvist, Karin Rudling, Niklas Sörlén, Karin Uhlin
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction About 20% of the adult population have chronic pain, often associated with psychological distress, sick leave and poor health. There are large variations in the clinical picture. A biopsychosocial approach is used in investigation and tr
Externí odkaz:
https://doaj.org/article/93f36022e6174df6a48105004400d141
Autor:
Victor Bloniecki, Henrik Zetterberg, Dag Aarsland, Patrizia Vannini, Hlin Kvartsberg, Bengt Winblad, Kaj Blennow, Yvonne Freund-Levi
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background The underlying disease mechanism of neuropsychiatric symptoms (NPS) in dementia remains unclear. Cerebrospinal fluid (CSF) biomarkers for synaptic and axonal degeneration may provide novel neuropathological information for their o
Externí odkaz:
https://doaj.org/article/702adf2721b04dae83251459e74298a1
Autor:
Pieter Jelle Visser, Lianne M. Reus, Johan Gobom, Iris Jansen, Ellen Dicks, Sven J. van der Lee, Magda Tsolaki, Frans R. J. Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, José Luís Molinuevo, Sebastiaan Engelborghs, Yvonne Freund-Levi, Lutz Froelich, Kristel Sleegers, Valerija Dobricic, Simon Lovestone, Johannes Streffer, Stephanie J. B. Vos, Isabelle Bos, ADNI, August B. Smit, Kaj Blennow, Philip Scheltens, Charlotte E. Teunissen, Lars Bertram, Henrik Zetterberg, Betty M. Tijms
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/bed6d4acfcca4b45a20fbe17c567341a
Autor:
Daniel R. Bateman, Sascha Gill, Sophie Hu, Erin D. Foster, Myuri T. Ruthirakuhan, Allis F. Sellek, Moyra E. Mortby, Veronika Matušková, Kok Pin Ng, Rawan M. Tarawneh, Yvonne Freund‐Levi, Sanjeev Kumar, Serge Gauthier, Paul B. Rosenberg, Fabricio Ferreira de Oliveira, D. P. Devanand, Clive Ballard, Zahinoor Ismail, for The International Society to Advance Alzheimer's Research and Treatment (ISTAART), Neuropsychiatric Syndromes Professional Interest Area (NPS‐PIA)
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract To identify knowledge gaps regarding new‐onset agitation and impulsivity prior to onset of cognitive impairment or dementia the International Society to Advance Alzheimer's Research and Treatment Neuropsychiatric Syndromes (NPS) Profession
Externí odkaz:
https://doaj.org/article/d5d0366d50aa49c6854120307afc6613
Autor:
Isabelle Bos, Frans R. Verhey, Inez H.G.B. Ramakers, Heidi I. L. Jacobs, Hilkka Soininen, Yvonne Freund-Levi, Harald Hampel, Magda Tsolaki, Åsa K. Wallin, Mark A. van Buchem, Ania Oleksik, Marcel M. Verbeek, Marcel Olde Rikkert, Wiesje M. van der Flier, Philip Scheltens, Pauline Aalten, Pieter Jelle Visser, Stephanie J. B. Vos
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2017)
Abstract Background Cerebrovascular disease (CVD) and amyloid-β (Aβ) often coexist, but their influence on neurodegeneration and cognition in predementia stages remains unclear. We investigated the association between CVD and Aβ on neurodegenerati
Externí odkaz:
https://doaj.org/article/f6e23b1d04cf42c0b25f254d50755cf1
Autor:
Jin Xu, Rebecca Green, Min Kim, Jodie Lord, Amera Ebshiana, Sarah Westwood, Alison L. Baird, Alejo J. Nevado-Holgado, Liu Shi, Abdul Hye, Stuart G. Snowden, Isabelle Bos, Stephanie J. B. Vos, Rik Vandenberghe, Charlotte E. Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen Elisa De Roeck, Sebastiaan Engelborghs, Kristel Sleegers, Régis Bordet, Lorena Rami, Petronella Kettunen, Magda Tsolaki, Frans R. J. Verhey, Daniel Alcolea, Alberto Lleó, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Giovanni B. Frisoni, José Luis Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez-Lage, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone, Petroula Proitsi, Cristina Legido-Quigley, on behalf of the European Medical Information Framework Consortium
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1610 (2021)
Background: physiological differences between males and females could contribute to the development of Alzheimer’s Disease (AD). Here, we examined metabolic pathways that may lead to precision medicine initiatives. Methods: We explored whether sex
Externí odkaz:
https://doaj.org/article/6a6c1bacf1644613b95016a016cd9ea8
Autor:
Betty Marije Tijms, Johan Gobom, Charlotte Teunissen, Valerija Dobricic, Magda Tsolaki, Frans Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, José Luís Molinuévo, Sebastiaan Engelborghs, Yvonne Freund-Levi, Lutz Froelich, Lars Bertram, Simon Lovestone, Johannes Streffer, Stephanie Vos, ADNI, Kaj Blennow, Philip Scheltens, Henrik Zetterberg, Pieter Jelle Visser
Publikováno v:
Proteomes, Vol 9, Iss 3, p 36 (2021)
We recently discovered three distinct pathophysiological subtypes in Alzheimer’s disease (AD) using cerebrospinal fluid (CSF) proteomics: one with neuronal hyperplasticity, a second with innate immune system activation, and a third subtype with blo
Externí odkaz:
https://doaj.org/article/ebb8c4b24c124b4abfc43b06cd30834d
Autor:
Simon Holmgren, Thomas Andersson, Anders Berglund, Dag Aarsland, Jeffrey Cummings, Yvonne Freund-Levi
Publikováno v:
J Neuropsychiatry Clin Neurosci
OBJECTIVE: Degenerative dementia is characterized by progressive cognitive decline and neuropsychiatric symptoms. People with Alzheimer’s disease (AD), the most common cause of dementia, show synaptic loss and disruption of functional brain network