Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yvonne Füll"'
Autor:
Karthika Devi Kiran Kumar, Shubhangi Singh, Stella Maria Schmelzle, Paul Vogel, Carolin Fruhner, Alfred Hanswillemenke, Adrian Brun, Jacqueline Wettengel, Yvonne Füll, Lukas Funk, Valentin Mast, J. Josephine Botsch, Philipp Reautschnig, Jin Billy Li, Thorsten Stafforst
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract RNA base editing relies on the introduction of adenosine-to-inosine changes into target RNAs in a highly programmable manner in order to repair disease-causing mutations. Here, we propose that RNA base editing could be broadly applied to per
Externí odkaz:
https://doaj.org/article/724df14e1cb54fe4a6a260b6d4615676
Autor:
Julia Koch-Heier, Annette B. Vogel, Yvonne Füll, Marina Ebensperger, Annika Schönsiegel, Raphael S. Zinser, Oliver Planz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Regulatory T cells (Tregs) play a crucial and complex role in balancing the immune response to viral infection. Primarily, they serve to regulate the immune response by limiting the expression of proinflammatory cytokines, reducing inflammation in in
Externí odkaz:
https://doaj.org/article/2a1c5d66cd4c42598f7e351f339bb757
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Zapnometinib is a MEK inhibitor currently under clinical development for the treatment of COVID-19 and influenza. Zapnometinib has both antiviral and immunomodulatory effects. Information concerning the absorption, distribution, metabolism, and excre
Externí odkaz:
https://doaj.org/article/cfe84751bb6847ae8fff09fb8064ee12
Autor:
Julia Koch-Heier, Annika Schönsiegel, Lara Maria Waidele, Julian Volk, Yvonne Füll, Christian Wallasch, Sebastian Canisius, Michael Burnet, Oliver Planz
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The mitogen-activated protein kinase (MEK) inhibitor zapnometinib is in development to treat acute viral infections like COVID-19 and influenza. While the antiviral efficacy of zapnometinib is well documented, further data on target engagement/pharma
Externí odkaz:
https://doaj.org/article/e3392661b71f4f1faa046b7781c6c23e
Autor:
Yvonne Füll, Lara Waidele, Hazem Hamza, Oliver Poetz, Andreas Steinhilber, Viktoria Anselm, Mark Delany, Judith van den Brand, Geert van Amerongen, Leon de Waal, Stephan Ludwig, Oliver Planz
Coronaviruses, in particular the current pandemic strains of SARS-CoV-2, represent an ever-evolving threat to human life. Currently available antiviral drugs are not suitable for severely infected patients in later hyperinflammatory stages of the dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ce27037debb6eacb9bd095c6fa837b
https://doi.org/10.21203/rs.3.rs-1381607/v1
https://doi.org/10.21203/rs.3.rs-1381607/v1
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:797-804
The voltage-gated potassium channels KV7.2 and KV7.3 (KCNQ2/3 genes) play an important role in regulating neuronal excitability. More than 50 KCNQ2/3 mutations have been identified to cause an inherited form of epilepsy in newborns. For two of those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b313a2e8ba59311735d08db51d4cacec
https://doi.org/10.1007/s00424-012-1184-x
https://doi.org/10.1007/s00424-012-1184-x