Localizing the lipid products of PI3Kγ in neutrophils

Autor: Arnaud Deladeriere, Hervé Guillou, Sabine Suire, Oliver Rausch, G. John Ferguson, Simon Andrews, Simon Walker, Tamara Chessa, Till Bretschneider, Cheng-Jin Du, Laura J. Norton, Anne Segonds-Pichon, Len R. Stephens, Takehiko Sasaki, Peter Finan, Yvonne E. Lindsay, Phillip T. Hawkins, John M. Lucocq

Publikováno v: Advances in Biological Regulation
Advances in Biological Regulation, 2016, 60, pp.36-45. ⟨10.1016/j.jbior.2015.10.005⟩
Advances in Biological Regulation (60), 36-45. (2016)

Class I phosphoinositide 3-kinases (PI3Ks) are important regulators of neutrophil migration in response to a range of chemoattractants. Their primary lipid products PtdIns(3,4,5)P3 and PtdIns(3,4)P2 preferentially accumulate near to the leading edge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ebb156550e35ea5bae9fafd142bb50

Migration Stimulating Factor (MSF) promotes fibroblast migration by inhibiting AKT

Autor: Ana M. Schor, Go Ohe, Seth L. Schor, Yvonne E. Lindsay, Nicolas R. Leslie, Sarah J. Jones, Ian R. Ellis

Publikováno v: Cellular Signalling. 22:1655-1659

The protein kinase AKT is activated strongly by many motogenic growth factors, yet has recently been shown capable of inhibiting migration in several cell types. Here we report that treatment with Migration Stimulating Factor (MSF), a truncated form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3689bc63b1769b61bdbfa608b6880715
https://doi.org/10.1016/j.cellsig.2010.06.005

Differential redox regulation within the PTP superfamily

Autor: Stephen T. Safrany, Michael J. Clague, Nick R. Leslie, Óscar Lorenzo, C. Peter Downes, Rachel Toth, Sarah H. Ross, Yvonne E. Lindsay, Fabrizio Villa

Publikováno v: Cellular Signalling. 19:1521-1530

The Protein Tyrosine Phosphatase (PTP) family comprises a large and diverse group of enzymes, regulating a range of biological processes through de-phosphorylation of many proteins and lipids. These enzymes share a catalytic mechanism that requires a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1e44286ab1e96810a0655a017cda6d
https://doi.org/10.1016/j.cellsig.2007.01.026

Identification of trehalose and glycine betaine as compatible solutes in the moderately halophilic sulfate reducing bacterium, Desulfovibrio halophilus

Autor: John Hannan, David T. Welsh, Yvonne E. Lindsay, Rodney A. Herbert, Pierre Caumette

Publikováno v: FEMS Microbiology Letters. 140:203-207

Increasing NaCl concentrations in the growth medium inhibited the growth of Desulfovibrio halophilus due to both an increase in the lag phase of growth and a reduction in the specific growth rate. Addition of 1 mM glycine betaine to the growth medium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::786d093e18bdd464ab59666e12c7647d
https://doi.org/10.1111/j.1574-6968.1996.tb08337.x

Zinc Levels in the Rat Fetal Liver are not Determined by Transport across the Placental Microvillar Membrane or the Fetal Liver Plasma Membrane1

Autor: H J McArdle, Yvonne E. Lindsay, Lesley M. Duthie

Publikováno v: Biology of Reproduction. 51:358-365

During pregnancy, zinc (Zn) levels in the rat fetal liver increase markedly. Why they do so or how the increase is regulated is unknown. We firstly investigated whether the increase occurs as a result of increased Zn transfer across the placenta and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a7b9bd316ee21faa1a36b7eea8a4c69
https://doi.org/10.1095/biolreprod51.3.358