Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yvonne Boergeling"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Restoring impaired peripheral immune tolerance is the primary challenge in treating autoimmune diseases. Our previous research demonstrated the effectiveness of small spleen peptides (SSPs), a fraction of low molecular weight prot
Externí odkaz:
https://doaj.org/article/ac3f29972f4c485e93914cd061931059
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Maintaining peripheral immune tolerance and preventing harmful autoimmune reactions is a fundamental task of the immune system. However, these essential functions are significantly compromised during autoimmune disorders, creating a major challenge i
Externí odkaz:
https://doaj.org/article/3cf02aee77fc453c80df48f5790f4a23
Autor:
Ramona Meissner, Viktor Wixler, Franziska Paulina Wulfert, Jasmin Carina Jacob, Benjamin G. Hale, Thomas Robeck, Dörthe Masemann, Yvonne Boergeling, Stephan Ludwig
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100741- (2023)
Low pathogenic influenza A viruses (IAVs) have shown promising oncolytic potential in lung cancer–bearing mice. However, as replication-competent pathogens, they may cause side effects in immunocompromised cancer patients. To circumvent this proble
Externí odkaz:
https://doaj.org/article/e049391d1543496e91f84abf9feb0076
Autor:
Verónica A. Ferrando, Marcel E. Friedrich, Shrey Gandhi, Alexander Mellmann, Dörthe Masemann, Anmari Christersson, Darisuren Anhlan, Linda Brunotte, Monika Stoll, Timm Harder, Martin Beer, Yvonne Boergeling, Stephan Ludwig
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTInfluenza A viruses (IAV) cause annual epidemics and occasional pandemics in humans. The most recent pandemic outbreak occurred in 2009 with H1N1pdm09. This virus, which most likely reassorted in swine before its transmission to humans, was r
Externí odkaz:
https://doaj.org/article/4a0d20eb3cce4efea4caca01d4f9af78
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 469 (2024)
Restoring peripheral immune tolerance is crucial for addressing autoimmune diseases. An ancient mechanism in maintaining the balance between inflammation and tolerance is the ratio of extracellular ATP (exATP) and adenosine. Our previous research dem
Externí odkaz:
https://doaj.org/article/d85ba9c30ede4d819acc0fbc3ca87f5a
Autor:
Angeles Mecate-Zambrano, Swathi Sukumar, Guiscard Seebohm, Kevin Ciminski, André Schreiber, Darisuren Anhlan, Lilo Greune, Ludmilla Wixler, Stephanie Grothe, Nora Caroline Stein, M Alexander Schmidt, Klaus Langer, Martin Schwemmle, Tianlai Shi, Stephan Ludwig, Yvonne Boergeling
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008775 (2020)
Small RNA viruses only have a very limited coding capacity, thus most viral proteins have evolved to fulfill multiple functions. The highly conserved matrix protein 1 (M1) of influenza A viruses is a prime example for such a multifunctional protein,
Externí odkaz:
https://doaj.org/article/fefccbf695be46aa806a99952163c902
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11164 (2021)
Influenza A viruses (IAVs) are respiratory pathogens that are able to hijack multiple cellular mechanisms to drive their replication. Consequently, several viral and cellular proteins undergo posttranslational modifications such as dynamic phosphoryl
Externí odkaz:
https://doaj.org/article/d6bfb87cf28e44f0851d7e7f1e9a8201
Publikováno v:
Viruses, Vol 13, Iss 10, p 2068 (2021)
Respiratory viruses are known to be the most frequent causative mediators of lung infections in humans, bearing significant impact on the host cell signaling machinery due to their host-dependency for efficient replication. Certain cellular functions
Externí odkaz:
https://doaj.org/article/f225979d409d4d379d375cab8ea05b22
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5486 (2021)
Influenza virus is a well-known respiratory pathogen, which still leads to many severe pulmonary infections in the human population every year. Morbidity and mortality rates are further increased if virus infection coincides with co-infections or sup
Externí odkaz:
https://doaj.org/article/c7788ab3fbd4413e8facf2e8cc27e778
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9289 (2020)
Medical research is changing into direction of precision therapy, thus, sophisticated preclinical models are urgently needed. In human pathogenic virus research, the major technical hurdle is not only to translate discoveries from animals to treatmen
Externí odkaz:
https://doaj.org/article/a2c40aface2046bba78e7732f644c795