Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Yvonne A. Lefebvre"'
Autor:
Amanda Carrigan, Laura Visentin, Ella Atlas, Gregory C. Addicks, Yanouchka Rouleau, Allison Edgecombe, Claudia Lamprecht, Yvonne A. Lefebvre, Robert J. G. Haché, Rhian F. Walther
Publikováno v:
Journal of Biological Chemistry. 280:17549-17561
The mineralocorticoid receptor (MR) is a tightly regulated nuclear hormone receptor that selectively transmits corticosteroid signals. Steroid treatment transforms MR from a transcriptionally inert state, in which it is distributed equally between th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdb218f176f3d8cd9928c1cf00a9bc0
https://doi.org/10.1074/jbc.m501548200
https://doi.org/10.1074/jbc.m501548200
Autor:
Isabelle Groulx, Stephen Lee, Andrew Ridsdale, Robert J. G. Haché, Yvonne A. Lefebvre, Rhian F. Walther, Claudia Lamprecht
Publikováno v:
Journal of Biological Chemistry. 278:37858-37864
Nucleocytoplasmic exchange of nuclear hormone receptors is hypothesized to allow for rapid and direct interactions with cytoplasmic signaling factors. In addition to recycling between a naïve, chaperone-associated cytoplasmic complex and a liganded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209205b25433402cd20a22c22ad1f6c4
https://doi.org/10.1074/jbc.m306356200
https://doi.org/10.1074/jbc.m306356200
Autor:
Yvonne A. Lefebvre, Claudia Lamprecht, Mingmin Liao, Gratien G. Prefontaine, Robert J. G. Haché, Rhian F. Walther, Joanne G.A. Savory
Publikováno v:
Molecular and Cellular Biology. 21:781-793
Steroid hormone receptors act to regulate specific gene transcription primarily as steroid-specific dimers bound to palindromic DNA response elements. DNA-dependent dimerization contacts mediated between the receptor DNA binding domains stabilize DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bb3cfc6a86b821fb8459b536eea808
https://doi.org/10.1128/mcb.21.3.781-793.2001
https://doi.org/10.1128/mcb.21.3.781-793.2001
Publikováno v:
Journal of Biological Chemistry. 274:1432-1439
Glucocorticoid receptor (GR) recycles between an inactive form complexed with heat shock proteins (hsps) and localized to the cytoplasm and a free liganded form that regulates specific gene transcription in the nucleus. We report here that, contrary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85ea23b9b08fdaff08a58c1806ecff7
https://doi.org/10.1074/jbc.274.3.1432
https://doi.org/10.1074/jbc.274.3.1432
Autor:
David J. Rodda, Yixian Zhang, Joanna Kwast-Welfeld, Gratien G. Prefontaine, Yvonne A. Lefebvre, Nancy L. Weigel, Ward Giffin, Robert J. G. Haché, Maya Traykova-Andonova
Publikováno v:
Journal of Biological Chemistry. 272:5647-5658
NRE1 is a DNA sequence element through which Ku antigen/DNA-dependent protein kinase (DNA-PK) catalytic subunit represses the induction of mouse mammary tumor virus transcription by glucocorticoids. Although Ku is an avid binder of DNA ends and has t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ab515dce0dd728ec9086766ad0f2595
https://doi.org/10.1074/jbc.272.9.5647
https://doi.org/10.1074/jbc.272.9.5647
Autor:
Yvonne Mignot-Lefebvre
Publikováno v:
Tiers-Monde. 37:339-357
Plus de trente ans se sont ecoules depuis la decolonisation ; ce mouve ment a cree de nouvelles souverainetes, lesquelles ont pris la forme d'Etats independants, le plus souvent de democraties, sur le modele occidental. Mais ces nouveaux Etats ne cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e08b2bd211a61bd0ee895189d705749
https://doi.org/10.3406/tiers.1996.5105
https://doi.org/10.3406/tiers.1996.5105
Autor:
Yvonne A. Lefebvre, Eric C. LaCasse
Publikováno v:
Nucleic Acids Research. 23:1647-1656
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f127b3eab527eb830f29f43f387a391
https://doi.org/10.1093/nar/23.10.1647
https://doi.org/10.1093/nar/23.10.1647
Publikováno v:
Endocrinology. 127:1087-1096
To exert their action at the genome, steroids must traverse the nuclear envelope, either alone or complexed to their receptor. Our previous studies identified two classes of dexamethasone-binding sites on male rat liver nuclear envelopes: a low capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336705e43a9a89eec6fa7ace094009ee
https://doi.org/10.1210/endo-127-3-1087
https://doi.org/10.1210/endo-127-3-1087
Autor:
Houssein Abdou Salem, Yvonne A. Lefebvre, Dongmei Wu, Robert J.G. Haché, Amanda Carrigan, Rhian F. Walther, Ella Atlas
Publikováno v:
The Journal of biological chemistry. 282(15)
The glucocorticoid receptor (GR) cycles between a naive chaperone-complexed form in the cytoplasm and a transcriptionally active steroid-bound nuclear form. Nuclear import of GR occurs rapidly and is mediated through the importin alpha/beta karyopher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecc4df5428f932c246258f457d8cf4a
https://pubmed.ncbi.nlm.nih.gov/17314103
https://pubmed.ncbi.nlm.nih.gov/17314103
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 16(12)
The effects of acetylation on gene expression are complex, with changes in chromatin accessibility intermingled with direct effects on transcriptional regulators. For the nuclear receptors, both positive and negative effects of acetylation on specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f95370054f9c9f80cc19b55b9b4bcde
https://pubmed.ncbi.nlm.nih.gov/12456802
https://pubmed.ncbi.nlm.nih.gov/12456802