Výsledky vyhledávání - "Yvonne A Yang"

Akademický článek

Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status

Autor: Yvonne S. Yang, Jason Smucny, Huailin Zhang, Richard J. Maddock

Publikováno v: NeuroImage: Clinical, Vol 39, Iss , Pp 103461- (2023)

Background: Brain metabolite abnormalities measured with magnetic resonance spectroscopy (MRS) provide insight into pathological processes in schizophrenia. Prior meta-analyses have not yet answered important questions about the influence of clinical

Externí odkaz: https://doaj.org/article/39253aede3f34ced8a3efd9d6be86c0f

Zobrazit plný text záznamu

Reimagining Merit and Representation: Promoting Equity and Reducing Bias in GME Through Holistic Review

Autor: Christine Wells, Sonya M Shadravan, Nicolás E Barceló, Katrina DeBonis, Yvonne S. Yang, Nichole Goodsmith, Trevor R. Shaddox, Brittany Tarrant, Eraka Bath

Publikováno v: Academic Psychiatry. 45:34-42

This study aims to evaluate the capacity of a holistic review process in comparison with non-holistic approaches to facilitate mission-driven recruitment in residency interview screening and selection, with particular attention to the promotion of ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8feff2d17ac20e0ad1830e0b40220356
https://doi.org/10.1007/s40596-020-01327-5

Zobrazit plný text záznamu

Brain glutathione levels and age at onset of illness in chronic schizophrenia

Autor: Michael F. Green, Gerhard Hellemann, Stephen R. Marder, Yvonne S. Yang, Junghee Lee, Richard J. Maddock, Huailin Zhang, Katherine L. Narr

Publikováno v: Acta Neuropsychiatrica. 31:343-347

Objective:Oxidative stress is implicated in the aetiology of schizophrenia, and the antioxidant defence system (AODS) may be protective in this illness. We examined the major antioxidant glutathione (GSH) in prefrontal brain and its correlates with c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6e4e825f020573a7f828b40ed71c1f
https://doi.org/10.1017/neu.2019.29

Zobrazit plný text záznamu

N-Acetylcysteine effects on glutathione and glutamate in schizophrenia: A preliminary MRS study

Autor: Yvonne S. Yang, Richard J. Maddock, Huailin Zhang, Junghee Lee, Gerhard Hellemann, Stephen R. Marder, Michael F. Green

Publikováno v: Psychiatry Research: Neuroimaging. 325:111515

N-acetylcysteine (NAC) is a commonly used antioxidant that may have beneficial effects for schizophrenia. In this double-blind, randomized, placebo-controlled preliminary study, 40 patients with schizophrenia or schizoaffective disorder were randomiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c04a88b15fae93eceb78a3898c6420
https://doi.org/10.1016/j.pscychresns.2022.111515

Zobrazit plný text záznamu

Akademický článek

Cre Stoplight: A Red/Green Fluorescent Reporter of Cre Recombinase Expression in Living Cells

Autor: Yvonne S. Yang, Thomas E. Hughes

Publikováno v: BioTechniques, Vol 31, Iss 5, Pp 1036-1041 (2001)

The Cre/lox system is a powerful genetic tool with which to manipulate the genome. Here, we describe the development of a simple reporter system for Cre recombinase, called the Cre Stoplight. In the absence of Cre, the red fluorescent protein is expr

Externí odkaz: https://doaj.org/article/03454841068c41ec96e5829afcd67a84

Zobrazit plný text záznamu

Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy volunteers

Autor: Joshua T. Kantrowitz, John H. Krystal, Tse-Hwei Choo, Jeffrey A. Lieberman, Melanie M. Wall, Guillermo Horga, Jack Grinband, Tarek Sobeih, Donald C. Goff, Stephen R. Marder, Yvonne S. Yang, Michael F. Green, Junghee Lee, Daniel C. Javitt, William Z. Potter, Ragy R. Girgis, Lawrence S. Kegeles, Adrienne C. Lahti

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 45, iss 11
Neuropsychopharmacology

Glutamate neurotransmission is a prioritized target for antipsychotic drug development. Two metabotropic glutamate receptor 2/3 (mGluR2/3) agonists (pomaglumetad [POMA] and TS-134) were assessed in two Phase Ib proof of mechanism studies of comparabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a428d2a66e88d01546be80d5bb2506
https://escholarship.org/uc/item/6q02z4dg

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání