Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Yvonne, Tay"'
Autor:
Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel Shao Weng Tan, Wai Leong Tam
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background The identification of cancer driver genes from sequencing data has been crucial in deepening our understanding of tumor biology and expanding targeted therapy options. However, apart from the most commonly altered genes, the mecha
Externí odkaz:
https://doaj.org/article/d7f9b649903749499dd3d17fb11e06b1
Autor:
Kuo-Chieh Liao, Xuping Xie, Anna Karin Beatrice Sundstrom, Xin Ni Lim, Kiat Kee Tan, Yu Zhang, Jing Zou, Amanda Makha Bifani, Hui Xian Poh, Jia Jia Chen, Wy Ching Ng, Su Ying Lim, Eng Eong Ooi, October M. Sessions, Yvonne Tay, Pei-Yong Shi, Roland G. Huber, Yue Wan
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Identifying host factors is key to understanding RNA virus pathogenicity. Besides proteins, RNAs can interact with virus genomes to impact replication. Results Here, we use proximity ligation sequencing to identify virus-host RNA
Externí odkaz:
https://doaj.org/article/47da49f037b74b8e94d5fc3d0069ec9f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3215 (2023)
Before the advent of next-generation sequencing, research on acute myeloid leukemia (AML) mostly centered on protein-coding genes. In recent years, breakthroughs in RNA sequencing technologies and whole transcriptome analysis have led to the discover
Externí odkaz:
https://doaj.org/article/3fe67dfac8f74c3c8ecb093cdb34802b
Autor:
Yongkang Long, Bin Zhang, Shuye Tian, Jia Jia Chan, Juexiao Zhou, Zhongxiao Li, Yisheng Li, Zheng An, Xingyu Liao, Yu Wang, Shiwei Sun, Ying Xu, Yvonne Tay, Wei Chen, Xin Gao
Publikováno v:
Genome Research. 33:644-657
Alternative polyadenylation (APA) enables a gene to generate multiple transcripts with different 3′ ends, which is dynamic across different cell types or conditions. Many computational methods have been developed to characterize sample-specific APA
Autor:
Hou, Weixin, Toh, Tan Boon, Abdullah, Lissa Nurrul, Yvonne, Tay Wei Zheng, Lee, Kuan J., Guenther, Ilonka, Chow, Edward Kai-Hua
Publikováno v:
In Nanomedicine: Nanotechnology, Biology, and Medicine April 2017 13(3):783-793
Autor:
Kourosh Zarringhalam, Yvonne Tay, Prajna Kulkarni, Assaf C. Bester, Pier Paolo Pandolfi, Rahul V. Kulkarni
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Regulation by microRNAs (miRNAs) and modulation of miRNA activity are critical components of diverse cellular processes. Recent research has shown that miRNA-based regulation of the tumor suppressor gene PTEN can be modulated by the expressi
Externí odkaz:
https://doaj.org/article/9eebffdf6a484073afb802d526c80efc
Autor:
Joanne Lee, Hossein Tabatabaeian, Michelle Limei Poon, Nagavalli Somasundaram, Liu Xin, Yi Ching Yuen, Chia Meng Teoh, Benedict Yan, Esther Hian Li Chan, Yen Lin Chee, Sanjay De Mel, Bin Zhang, Xiao Hong Chew, Tiffany Tang, Chiea Chuen Khor, Joanne Yuen Yie Ngeow, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, E Shyong Tai, Kee Yuan Ngiam, Soo Chin Lee, Boon Cher Goh, Anand Devaprasath D. Jeyasekharan, Yvonne Tay, Folefac Aminkeng
Publikováno v:
Blood. 140:4542-4544
Autor:
Zhongxiao Li, Bin Zhang, Jia Jia Chan, Hossein Tabatabaeian, Qing Yun Tong, Xiao Hong Chew, Xiaonan Fan, Patrick Driguez, Charlene Chan, Faith Cheong, Shi Wang, Bei En Siew, Ian Jse-Wei Tan, Kai-Yin Lee, Bettina Lieske, Wai-Kit Cheong, Dennis Kappei, Ker-Kan Tan, Xin Gao, Yvonne Tay
SummaryColorectal cancer (CRC) is the second leading cause of cancer death worldwide. In recent years, short-read single-cell RNA sequencing (scRNA-seq) has been instrumental in deciphering tumor cell heterogeneities. However, these studies only enab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::164d871344c44357378d920899e1d765
https://doi.org/10.1101/2023.04.21.536771
https://doi.org/10.1101/2023.04.21.536771
Autor:
Yvonne Tay, Dennis Kappei, Henry Yang, Velda Teh, Jia Jia Chan, Xiao Hong Chew, Bin Zhang, Zhi Hao Kwok
Approximately half of all miRNA reside within intronic regions and are often cotranscribed with their host genes. However, most studies of intronic miRNA focus on individual miRNA, while conversely most studies of protein-coding and noncoding genes f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63593126ebae55bca22377bbfb8d37d8
https://doi.org/10.1158/0008-5472.c.6512451
https://doi.org/10.1158/0008-5472.c.6512451
Autor:
Yvonne Tay, Dennis Kappei, Henry Yang, Velda Teh, Jia Jia Chan, Xiao Hong Chew, Bin Zhang, Zhi Hao Kwok
Figure S1 showing FTX-derived miRNAs are upregulated in colon cancer patients. Figure S2 showing FTX possesses oncogenic properties in colon cancer. Figure S3 showing FTX interacts with DHX9 and DICER. Figure S4 showing intronic miR-374b and -545 pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a417d9c5e9613090990c11f142bb9c5
https://doi.org/10.1158/0008-5472.22426788
https://doi.org/10.1158/0008-5472.22426788