Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yvonne, Hofmann"'
Autor:
Marta Sánchez-Carbonell, Patricia Jiménez Peinado, Cathrin Bayer-Kaufmann, Jean-Christopher Hennings, Yvonne Hofmann, Silvio Schmidt, Otto W. Witte, Anja Urbach
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Single-cell RNA sequencing (scRNA-seq) provides a powerful tool to evaluate the transcriptomic landscape and heterogeneity of thousands of cells in parallel. However, complex study designs or the unavailability of in-house instruments require the tem
Externí odkaz:
https://doaj.org/article/7a5bc465502c4afbb0f6f3897d5f453e
Autor:
Quratul, Ain, Christian W, Schmeer, Diane, Wengerodt, Yvonne, Hofmann, Otto W, Witte, Alexandra, Kretz
Publikováno v:
International journal of molecular sciences. 23(6)
Efficient purification of viable neural cells from the mature CNS has been historically challenging due to the heterogeneity of the inherent cell populations. Moreover, changes in cellular interconnections, membrane lipid and cholesterol compositions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c739aad63a08b598de70845bc60f0d7
https://pubmed.ncbi.nlm.nih.gov/35328432
https://pubmed.ncbi.nlm.nih.gov/35328432
Autor:
Brunhilde Wirth, L. Brichta, E. Hahnen, Yvonne Hofmann, Ilker Y. Eyüpoglu, Heidrun Raschke, Ingmar Blümcke, Florian A. Siebzehnrubl
Publikováno v:
Human Molecular Genetics. 12:2481-2489
Proximal spinal muscular atrophy (SMA) is a common neuromuscular disorder causing infant death in half of all patients. Homozygous absence of the survival motor neuron gene (SMN1) is the primary cause of SMA, while SMA severity is mainly determined b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d426b0f3bca31c90f023ea90b2413ed
https://doi.org/10.1093/hmg/ddg256
https://doi.org/10.1093/hmg/ddg256
Publikováno v:
Journal of Geodynamics. 35:209-220
The occurrence of swarm earthquakes in the Vogtland/NW-Bohemia area results probably from the physical interactions of fluids, the stress field and the geometry of the geological units. Therefore the present study aims at the development of a 3-D den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abd93593a40b5feb83e1b5bc4b7b2b00
https://doi.org/10.1016/s0264-3707(02)00063-7
https://doi.org/10.1016/s0264-3707(02)00063-7
Publikováno v:
Scopus-Elsevier
Spinal muscular atrophy (SMA), a common motor neuron disease in humans, results from loss of functional survival motor neuron ( SMN1 ) alleles. A nearly identical copy of the gene, SMN2 , fails to provide protection from SMA because of a single trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fe38457279c9ec7cb2cf98d3e53a8c
https://doi.org/10.1073/pnas.160181697
https://doi.org/10.1073/pnas.160181697
Autor:
Ellie Landman, Souren Mkrtchian, Yvonne Hofmann, Isa Cavaco, Jana Nekvindová, Magnus Ingelman-Sundberg, Rasmus Steen Pedersen, Jessica Mwinyi
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
CYP2C9 is an important drug-metabolizing enzyme that metabolizes, e. g., warfarin, antidiabetics, and antiphlogistics. However, the endogenous regulation of this enzyme is largely unknown. In this study, we examined the role of GATA transcription fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a3a49b760516e4b9ccf9b7e6d9499a
https://pubmed.ncbi.nlm.nih.gov/19995889
https://pubmed.ncbi.nlm.nih.gov/19995889
Autor:
Jana Nekvindová, Isa Cavaco, Souren Mkrtchian, Yvonne Hofmann, Rasmus Steen Pedersen, Magnus Ingelman-Sundberg, Jessica Mwinyi
Publikováno v:
Life sciences. 86(19-20)
Aims Cytochrome P4502C19 (CYP2C19) is an important enzyme involved in the metabolism of antiulcer drugs and antidepressants. However, despite the well documented drug-dependent variability of CYP2C19 expression, the mechanisms underlying the regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30a4225faa9c8956d678baca56184b7
https://pubmed.ncbi.nlm.nih.gov/20206639
https://pubmed.ncbi.nlm.nih.gov/20206639
Autor:
Xue-Qing Li, Inger Johansson, Tommy B. Andersson, Åsa Nordling, Sabina Nivelius, Yvonne Hofmann, Magnus Ingelman-Sundberg, Susanne Andersson
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 33(4)
The enzymic basis for intracellular reduction of N-hydroxylated amidines to their corresponding amidines, and hydroxylamines to their corresponding amines, is unknown. The hydroxylated amidines can be used as prodrug moieties, and an understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd731a36ef6853a2491c4d9db8de8be5
https://pubmed.ncbi.nlm.nih.gov/15640373
https://pubmed.ncbi.nlm.nih.gov/15640373
Autor:
Sabine Rudnik-Schöneborn, Frank Schoenen, Klaus Zerres, Heidrun Raschke, Gabriela E. Oprea, Brunhilde Wirth, Yvonne Hofmann, Claudia Helmken
Publikováno v:
Human genetics. 114(1)
Proximal spinal muscular atrophy (SMA) is a neuromuscular disorder caused by homozygous mutations of the SMN1 gene. SMN1 interacts with multiple proteins with functions in snRNP biogenesis, pre-mRNA splicing and presumably neural transport. SMN2, a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8cece801bd4b836bac27e5e64dbef8
https://pubmed.ncbi.nlm.nih.gov/14520560
https://pubmed.ncbi.nlm.nih.gov/14520560
Autor:
Brunhilde Wirth, Yvonne Hofmann
Publikováno v:
Human molecular genetics. 11(17)
Proximal spinal muscular atrophy (SMA) is a common motor neuron disease caused by homozygous loss of the survival motor neuron gene (SMN1). SMN2, a nearly identical copy of the gene and present in all SMA patients, fails to provide protection from SM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368d83cb58bf0885c161487c0cf2b266
https://pubmed.ncbi.nlm.nih.gov/12165565
https://pubmed.ncbi.nlm.nih.gov/12165565