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Ultra-performance liquid chromatography for quantification of amphotericin B plasma concentrations after use of liposomal amphotericin B

Autor: Joost Wauters, Sander Croes, Yvo de Beer, Johan Maertens, Roger J. M. Brüggemann, Isabel Spriet, Rob E. Aarnoutse, Ruth Van Daele

Publikováno v: Journal of Antimicrobial Chemotherapy, 76, 961-966
Journal of Antimicrobial Chemotherapy, 76(4), 961-966. Oxford University Press
Journal of Antimicrobial Chemotherapy, 76, 4, pp. 961-966

ObjectivesLiposomal amphotericin B is widely used to treat life-threatening invasive fungal infections and has replaced conventional amphotericin B deoxycholate due to its more favourable toxicity profile. Despite the fact that liposomal amphotericin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c800e7e18f0ee441b6dc000707c5319
https://doi.org/10.1093/jac/dkaa515

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Liposomal amphotericin B exposure in critically ill patients: a prospective pharmacokinetic study

Autor: Ruth Van Daele, Joost Wauters, Omar Elkayal, Erwin Dreesen, Yves Debaveye, Katrien Lagrou, Yvo de Beer, Johan Maertens, Roger J Brüggemann, Isabel Spriet

Publikováno v: Medical Mycology, 60
Medical Mycology. Informa Healthcare
Medical Mycology, 60, 10

Liposomal amphotericin B (L-AmB) is a broad-spectrum antifungal drug. Little is known about its pharmacokinetics (PK) in critically ill patients. The aim of this study was to document the PK of L-AmB in this population. It was also explored if covari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21489093093e702b45167dec384585f6
http://hdl.handle.net/2066/287857

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Development and validation of an HPLC-MS/MS method to simultaneously quantify alectinib, crizotinib, erlotinib, gefitinib and osimertinib in human plasma samples, using one assay run

Autor: Roy Schoufs, Sander Croes, Leo M L Stolk, Ard van Veelen, Robin M. J. M. van Geel, Yvo de Beer, Lizza E.L. Hendriks

Publikováno v: Biomedical Chromatography, 35(12):e5224. John Wiley & Sons Inc.

A liquid chromatography-tandem mass spectrometry method was developed and validated to quantify alectinib, crizotinib, erlotinib and gefitinib. This assay can be combined with our method for osimertinib, allowing quantification of the most used ALK-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e925fd334e3f034ad97627b5e60c1a9
https://cris.maastrichtuniversity.nl/en/publications/7e6fc3c6-8b8e-44d3-90f2-417723b90448

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Fixed Dosing of Liposomal Amphotericin B in Morbidly Obese Individuals

Autor: Roeland E Wasmann, Cornelis Smit, Roger J. M. Brüggemann, René M J Wiezer, Jill Adler-Moore, David M. Burger, Eric P H van Dongen, Yvo de Beer, Catherijne A. J. Knibbe

Publikováno v: Clinical Infectious Diseases, 70, 2213-2215
Clinical Infectious Diseases, 70(10):ciz885, 2213-2215. Oxford University Press
Clinical Infectious Diseases, 70(10), 2213-2215. Oxford University Press
Clinical Infectious Diseases, 70, 10, pp. 2213-2215

Contains fulltext : 220654.pdf (Publisher’s version ) (Open Access) In this prospective study, we examined the pharmacokinetics of 1 and 2 mg/kg liposomal amphotericin B in 16 morbidly obese individuals (104-177 kg). Body size had no effect on clea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d36f3cb7b06cf3257c701d5b4da6ba
https://doi.org/10.1093/cid/ciz885

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Validation of an analytical method using HPLC-MS/MS to quantify osimertinib in human plasma and supplementary stability results

Autor: Sander Croes, Yvo de Beer, Robin M. J. M. van Geel, Anne-Marie C. Dingemans, Ard van Veelen, Frank de Vries, Rob ter Heine, Leo M L Stolk

Publikováno v: Biomedical Chromatography, 34, 4, pp. e4771
Biomedical Chromatography, 34, e4771
Biomedical Chromatography, 34(4), 1. John Wiley and Sons Ltd
Biomedical Chromatography, 34(4):e4771. John Wiley & Sons Inc.

Contains fulltext : 218134.pdf (Publisher’s version ) (Closed access) A new method for quantification of osimertinib (OSIM) in human plasma using a high-performance liquid chromatography-tandem mass spectrometry method was developed and validated.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ba3860be9ffcb8a98f56076d9d06c9
https://doi.org/10.1002/bmc.4771

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Correlation of toxicity and efficacy with pharmacokinetics (PK) of pegylated liposomal doxorubicin (PLD) (Caelyx(A (R)))

Autor: Mirjam G. W. Arens van der Logt, Petronella B. Ottevanger, Winette T. A. van der Graaf, Carla M.L. van Herpen, Marye J Boers-Sonderen, Ingrid M.E. Desar, Yvo de Beer, Nielka P. van Erp

Publikováno v: Cancer Chemotherapy and Pharmacology, 74(3), 457-463. Springer Verlag
Cancer Chemotherapy and Pharmacology, 74, 457-63
Cancer Chemotherapy and Pharmacology, 74, 3, pp. 457-63

Item does not contain fulltext PURPOSE: Pegylated liposomal doxorubicin (PLD) is used to treat patients with breast and gynecological cancers. In order to optimize treatment with PLD, we assessed the prognostic and predictive factors for efficacy of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3b98b44b42fa3c47aa57fa88ab889d
https://cris.maastrichtuniversity.nl/en/publications/15e5e2b0-7f51-4c04-a215-5ed50c6b914c

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