Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yvette van Loon"'
Autor:
Rania Ghouil, Simona Miron, Lieke Koornneef, Jasper Veerman, Maarten W. Paul, Marie-Hélène Le Du, Esther Sleddens-Linkels, Sari E. van Rossum-Fikkert, Yvette van Loon, Natalia Felipe-Medina, Alberto M. Pendas, Alex Maas, Jeroen Essers, Pierre Legrand, Willy M. Baarends, Roland Kanaar, Sophie Zinn-Justin, Alex N. Zelensky
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
BRCA2 and its interactor HSF2BP are required for meiotic recombination. Here, the authors define the interaction structurally, revealing that a repeat in BRCA2 binds two HSF2BP units, increasing the affinity. This region is, however, not essential fo
Externí odkaz:
https://doaj.org/article/0b53e0fe0b894a1fac23825f31a88406
Autor:
Marie-Hélène Le Du, Maarten W. Paul, Roland Kanaar, Esther Sleddens-Linkels, Rania Ghouil, Alberto M. Pendás, Pierre Legrand, Lieke Koornneef, Yvette van Loon, Natalia Felipe-Medina, Jasper Veerman, Alex N. Zelensky, Jeroen Essers, Willy M. Baarends, Sari E. van Rossum-Fikkert, Sophie Zinn-Justin, Alex Maas, Simona Miron
Publikováno v:
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 12(1):4605. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 12(1):4605. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
© The Author(s) 2021.
BRCA2 and its interactors are required for meiotic homologous recombination (HR) and fertility. Loss of HSF2BP, a BRCA2 interactor, disrupts HR during spermatogenesis. We test the model postulating that HSF2BP localizes BR
BRCA2 and its interactors are required for meiotic homologous recombination (HR) and fertility. Loss of HSF2BP, a BRCA2 interactor, disrupts HR during spermatogenesis. We test the model postulating that HSF2BP localizes BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b99781f32df629289d3166479d9c2f
https://doi.org/10.1038/s41467-021-24871-6
https://doi.org/10.1038/s41467-021-24871-6
Autor:
Roland Kanaar, Pierre Legrand, Alex Maas, Simona Miron, Maarten W. Paul, Rania Ghouil, Lieke Koornneef, Alberto M. Pendás, Jasper Veerman, Esther Sleddens-Linkels, Sari E. van Rossum-Fikkert, Marie-Hélène Le Du, Sophie Zinn-Justin, Willy M. Baarends, Alex N. Zelensky, Jeroen Essers, Natalia Felipe-Medina, Yvette van Loon
BRCA2 plays a prominent role in meiotic homologous recombination (HR). Loss of BRCA2 or several of its meiotic partners causes fertility defects. One of these partners, HSF2BP, was recently discovered as expressed physiologically in germline and ecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa2d17b626d9e0e3401e1933aa2123f1
https://doi.org/10.1101/2020.12.29.424679
https://doi.org/10.1101/2020.12.29.424679
