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pro vyhledávání: '"Yvette Weinrauch"'
Autor:
Anne Mayer-Scholl, Robert Hurwitz, Volker Brinkmann, Monika Schmid, Peter Jungblut, Yvette Weinrauch, Arturo Zychlinsky
Publikováno v:
PLoS Pathogens, Vol 1, Iss 3, p e23 (2005)
Bacillus anthracis spores cause natural infections and are used as biological weapons. Inhalation infection with B. anthracis, the etiological agent of anthrax, is almost always lethal, yet cutaneous infections usually remain localized and resolve sp
Externí odkaz:
https://doaj.org/article/df762b73efe7493889c85cf3aa58c02a
Autor:
Björn Eilers, Travis Walker, Yvette Weinrauch, Arturo Zychlinsky, Christoph M. Tang, Anne Mayer-Scholl
Publikováno v:
Cellular Microbiology. 12:1134-1143
Shigella flexneri is an enteric pathogen that causes massive inflammation and destruction of the human intestinal epithelium. Neutrophils are the first cells of the innate immune system recruited to the site of infection. These cells can attack micro
Autor:
Christian Goosmann, Arturo Zychlinsky, Volker Wahn, Ulrike Abu Abed, Yvette Weinrauch, Volker Brinkmann, Robert Hurwitz, Ilka Schulze, Tobias A. Fuchs
Publikováno v:
The Journal of Cell Biology
Neutrophil extracellular traps (NETs) are extracellular structures composed of chromatin and granule proteins that bind and kill microorganisms. We show that upon stimulation, the nuclei of neutrophils lose their shape, and the eu- and heterochromati
Autor:
David S. Weiss, Yvonne Uhlemann, Yvette Weinrauch, Arturo Zychlinsky, Beatrix Fauler, Christian Goosmann, Volker Brinkmann, Ulrike Reichard
Publikováno v:
Science. 303:1532-1535
Neutrophils engulf and kill bacteria when their antimicrobial granules fuse with the phagosome. Here, we describe that, upon activation, neutrophils release granule proteins and chromatin that together form extracellular fibers that bind Gram-positiv
Publikováno v:
Nature. 417:91-94
Shigellae cause bacillary dysentery, a bloody form of diarrhoea that affects almost 200 million people and causes nearly 2 million deaths per year1. Shigella invades the colonic mucosa, where it initiates an acute inflammation, rich in neutrophils, t
Autor:
Arturo Zychlinsky, Yvette Weinrauch
Publikováno v:
Annual Review of Microbiology. 53:155-187
▪ Abstract Apoptosis is a highly regulated process of cell death that is required for the development and homeostasis of multicellular organisms. In contrast to necrosis, apoptosis eliminates individual cells without inducing an inflammatory respon
Publikováno v:
Journal of Clinical Investigation. 103:715-721
We have shown previously that a group IIA phospholipase A2 (PLA2) is responsible for the potent bactericidal activity of inflammatory fluids against many Gram-positive bacteria. To exert its antibacterial activity, this PLA2 must first bind and trave
Publikováno v:
Journal of Clinical Investigation. 102:633-638
Extracellular mobilization of Group IIA 14-kD phospholipase A2 (PLA2) in glycogen-induced rabbit inflammatory peritoneal exudates is responsible for the potent bactericidal activity of the inflammatory fluid toward Staphylococcus aureus (1996. J. Cli
Publikováno v:
Journal of Clinical Investigation. 97:250-257
The cell-free fluid (ascitic fluid, AF) of a sterile inflammatory peritoneal exudate elicited in rabbits is potently bactericidal for complement-resistant gram-negative as well as gram-positive bacterial species. This activity is absent in plasma. We
Autor:
Yvette Weinrauch, Martin J. Blaser, Seema K. Pursnani, Nicole M. Iovine, Gregory A. Wasserman, Alex Voldman
Publikováno v:
Infection and immunity. 76(3)
Campylobacter jejuni, a gram-negative, invasive organism, is a common cause of food-borne bacterial diarrheal disease. However, the relationship betweenC. jejuniand the innate immune system is not well described. To better characterize host defense a