Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Yvette Torrens"'
Autor:
Yvette Torrens, Sandra Jimena Hernández Vallejo, Jean-Pol Tassin, Emilie Lucie Doucet, Vanessa Houades, G. Godeheu, Christophe Lanteri, Lucas Salomon
Publikováno v:
The Journal of Neuroscience. 29:987-997
Although nicotine is generally considered to be the main compound responsible for addictive properties of tobacco, experimental data indicate that nicotine does not exhibit all the characteristics of other substances of abuse. We recently showed that
Publikováno v:
International Journal of Peptide and Protein Research. 21:254-257
The synthesis of two glycosylated analogs of Substance P is described. The activity of the peptides was assayed on the isolated guinea-pig ileum and their degradation was studied using rat hypothalamus slices. While glycosylation noticeably enhances
Publikováno v:
Journal of Neurochemistry. 79:985-996
Attempts were made to label tachykinin NK2 binding sites in the adult rat brain using [125I]neurokinin A (NKA) as ligand in the presence of NK1 and NK3 agonist or antagonist to avoid labelling of NK1 and NK3 binding sites, respectively. A high-affini
Publikováno v:
Peptides. 25:339-357
Several aspects of our 25 year adventure in the field of tachykinins will be successively described. They concern: substance P (SP) synthesis and release in the basal ganglia, the identification and pharmacological characterization of central tachyki
Autor:
François Couraud, Joël Prémont, Yvette Torrens, Joël Bockaert, Philippe Marin, Laurent Fagni, Jacques Glowinski, Gisèle Alcaraz
Publikováno v:
European Journal of Neuroscience. 14:1953-1960
Glutamatergic transmission is mediated by ionotropic receptors that directly gate cationic channels and metabotropic receptors that are coupled to second messenger generating systems and to ionic channels via heterotrimeric guanine-nucleotide binding
Publikováno v:
Peptides. 20:1347-1352
Binding studies have shown that [ 125 I]NKA is a selective ligand of tachykinin septide-sensitive binding sites from membranes of the rat submaxillary gland. Indeed, this ligand bound with high affinity to a single population of sites. In addition, c
Autor:
Jacques Glowinski, Christian Giaume, Yvette Torrens, Jocelyne Cordier, Laurent Venance, Sandrine Sagan
Publikováno v:
European Journal of Neuroscience. 11:691-699
The effects of anandamide and the cannabinoid receptor agonists WIN 55212-2 and CP 55940 on the evoked formation of cyclic AMP were compared in cultured neurons and astrocytes from the cerebral cortex and striatum of mouse embryos. The three compound
Autor:
Jacques Glowinski, S. Lavielle, Jean-Claude Beaujouan, Monique Saffroy, G. Chassaing, Sandrine Sagan, Yvette Torrens
Publikováno v:
Scopus-Elsevier
Propionyl-[Met(O2)11]substance P(7-11) [ALIE-124 or propionyl-[Met(O2)11]SP(7-11)] has been designed as a septide-like ligand adequate for tritiation and, therefore, adequate for binding studies. In Chinese hamster ovary (CHO) cells expressing human
Publikováno v:
European Journal of Pharmacology. 319:307-316
Binding studies indicated that tachykinin NK3 binding sites in peripheral (ileum) and central (cerebral cortex) tissues of the guinea pig exhibit similar pharmacological properties. They also confirmed that the tachykinin NK3 receptor antagonist (S)-
Publikováno v:
Peptides. 16:587-594
The selective NK2 agonist [Lys5,MeLeu9,Nle10]NKA(4–10) markedly stimulated [3H]inositol monophosphate (IP1) formation in prisms from the rat urinary bladder. This response was blocked by the NK2 antagonist SR 48968. Senktide (NK3 agonist) was inact