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Autor:
Paul L. Hallenbeck, J. Andrew Bristol, Kiran Sakhuja, Dawn B. Kayda, Michael Kaleko, Yvette Hudson, John L. Jakubczak, Sheila Connelly, David L. Ennist, Kevin D. Burroughs
Publikováno v:
Cancer Gene Therapy. 11:92-102
Oncolytic adenoviral vectors selectively replicate in and lyse human tumor cells, providing a promising means for targeted tumor destruction. However, oncolytic vectors have limited capacity for incorporation of additional genetic material that could