Manufacturing and Characterization of a Recombinant Adeno-Associated Virus Type 8 Reference Standard Material

Autor: Xinhua Zhang, Mauro Giacca, Mauricio R. Alvira, Xavier León, Catherine Pythoud, Alberto Auricchio, Lorena Zentilin, Will Fountain, Marcus Müller, Christophe Darmon, Martin Lock, Olivier Bockstael, Hiroaki Mizukami, Eduard Ayuso, Keiya Ozawa, Brigitte Weins, Susan P. McGorray, Kai Gao, Barbara Leuchs, Monica Doria, Yvet Noordman, Fatima Bosch, J. Fraser Wright, K. Reed Clark, Catherine Melas, Philippe Moullier, Véronique Blouin, Stephanie Bucher, Liliane Tenenbaum, Juergen Dr Kleinschmidt, Marina Sumaroka, Richard O. Snyder, Abdelwahed Chtarto, Inge van der Linden, Guangping Gao, Richard T. Surosky

Publikováno v: Human Gene Therapy
Human Gene Therapy, Mary Ann Liebert, 2014, 25 (11), pp.977-987. ⟨10.1089/hum.2014.057⟩
Human Gene Therapy, 2014, 25 (11), pp.977-987. ⟨10.1089/hum.2014.057⟩
Human Gene Therapy, vol. 25, no. 11, pp. 977-987

Gene therapy approaches using recombinant adeno-associated virus serotype 2 (rAAV2) and serotype 8 (rAAV8) have achieved significant clinical benefits. The generation of rAAV Reference Standard Materials (RSM) is key to providing points of reference

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63fbfb64391b66e543280f2b0942e2c
https://europepmc.org/articles/PMC4236062/