Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.

Autor: Evan Quon, Yves Y Sere, Neha Chauhan, Jesper Johansen, David P Sullivan, Jeremy S Dittman, William J Rice, Robin B Chan, Gilbert Di Paolo, Christopher T Beh, Anant K Menon

Publikováno v: PLoS Biology, Vol 16, Iss 5, p e2003864 (2018)

Tether proteins attach the endoplasmic reticulum (ER) to other cellular membranes, thereby creating contact sites that are proposed to form platforms for regulating lipid homeostasis and facilitating non-vesicular lipid exchange. Sterols are synthesi

Externí odkaz: https://doaj.org/article/efa2ddef75a04ab9ab955fc705402e73

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

Autor: Alberto T Gatta, Louise H Wong, Yves Y Sere, Diana M Calderón-Noreña, Shamshad Cockcroft, Anant K Menon, Tim P Levine

Publikováno v: eLife, Vol 4 (2015)

Sterol traffic between the endoplasmic reticulum (ER) and plasma membrane (PM) is a fundamental cellular process that occurs by a poorly understood non-vesicular mechanism. We identified a novel, evolutionarily diverse family of ER membrane proteins

Externí odkaz: https://doaj.org/article/5e7eaabd41d4422a863124ee74eb6141

Increased fatty acid synthesis inhibits nitrogen starvation-induced autophagy in lipid droplet-deficient yeast

Autor: Pierre Voisin, Yves Y. Sere, François-Xavier Bernard, Christine Barrault, Venty M.S. Soeroso, Bin Wan, Thierry Bergès, Marianne Bernard, Matthieu Régnacq, Nadine Camougrand

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2016, 477 (1), pp.33-39. ⟨10.1016/j.bbrc.2016.06.017⟩

Biologie végétale; International audience; Macroautophagy is a degradative pathway whereby cells encapsulate and degrade cytoplasmic material within endogenously-built membranes. Previous studies have suggested that autophagosome membranes originat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec5f08860018d745b41ad9cc60a7b2d
https://doi.org/10.1016/j.bbrc.2016.06.017

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation

Autor: Jeremy S. Dittman, Jesper Johansen, Christopher T. Beh, Anant K. Menon, Evan Quon, Neha Chauhan, Robin B. Chan, William J. Rice, Yves Y. Sere, David P. Sullivan, Gilbert Di Paolo

Publikováno v: PLoS Biology, Vol 16, Iss 5, p e2003864 (2018)
PLoS Biology

Tether proteins attach the endoplasmic reticulum (ER) to other cellular membranes, thereby creating contact sites that are proposed to form platforms for regulating lipid homeostasis and facilitating non-vesicular lipid exchange. Sterols are synthesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1555b79edad4d510ec8cc3077d6e97a8
https://doaj.org/article/efa2ddef75a04ab9ab955fc705402e73

Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane

Autor: Daniel Wüstner, Azra Pizovic, Yves Y. Sere, Anant K. Menon, Katarzyna A. Solanko, Lukasz M. Solanko, Thomas Günther Pomorski, Anita Lunding, Lyubomir Dimitrov Stanchev, Maria Szomek, David P. Sullivan

Publikováno v: Solanko, L M, Sullivan, D P, Sere, Y Y, Szomek, M, Lunding, A, Solanko, K A, Pizovic, A, Stanchev, L D, Pomorski, T G, Menon, A K & Wüstner, D 2018, ' Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane ', Traffic, vol. 19, no. 3, pp. 198-214 . https://doi.org/10.1111/tra.12545

Transbilayer lipid asymmetry is a fundamental characteristic of the eukaryotic cell plasma membrane (PM). While PM phospholipid asymmetry is well documented, the transbilayer distribution of PM sterols such as mammalian cholesterol and yeast ergoster

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1da610c1c5e24bf29e807684ffb79d
https://findresearcher.sdu.dk:8443/ws/files/141818799/Ergosterol_is_mainly_located_in_the_cytoplasmic_leaflet_of_the_yeast_plasma_membrane.pdf