Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yves Théoret"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Mean arterial pressure to mean pulmonary arterial pressure ratio (mAP/mPAP) has been identified as a strong predictor of perioperative complications in cardiac surgery. We therefore investigated the pharmacokinetic/pharmacodynamic (PK/PD) re
Externí odkaz:
https://doaj.org/article/f06a60f85b954575ada135c1e1b8ffab
Autor:
Khalil Ben Hassine, Tiago Nava, Yves Théoret, Christa E. Nath, Youssef Daali, Nastya Kassir, Victor Lewis, Robbert G. M. Bredius, Peter J. Shaw, Henrique Bittencourt, Maja Krajinovic, Chakradhara Rao Satyanarayana Uppugunduri, Marc Ansari
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 1043-1056 (2021)
Abstract Busulfan (Bu) is a common component of conditioning regimens before hematopoietic stem cell transplantation (HSCT) and is known for high interpatient pharmacokinetic (PK) variability. This study aimed to develop and externally validate a mul
Externí odkaz:
https://doaj.org/article/4a2a660863bf4f659cde9d7b20f139cd
Autor:
Sébastien Perreault, Valérie Larouche, Uri Tabori, Cynthia Hawkin, Sarah Lippé, Benjamin Ellezam, Jean-Claude Décarie, Yves Théoret, Marie-Élaine Métras, Serge Sultan, Édith Cantin, Marie-Ève Routhier, Maxime Caru, Geneviève Legault, Éric Bouffet, Lucie Lafay-Cousin, Juliette Hukin, Craig Erker, Nada Jabado
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Pediatric low-grade gliomas (PLGG) are the most frequent brain tumors in children. Up to 50% will be refractory to conventional chemotherapy. It is now known that the majority of PLGG have activation of the MAPK/ERK pathway. The s
Externí odkaz:
https://doaj.org/article/e66eabef1a354091978ff8f6087684a2
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Inhaled milrinone administered before cardiopulmonary bypass (CPB) reduces the severity of pulmonary hypertension during cardiac surgery. However, milrinone pharmacokinetics has not been determined for this route of administration. The objective of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e5a0601fae79bccbd1bd6b0caa0864
http://link.springer.com/article/10.1038/s41598-020-58902-x
http://link.springer.com/article/10.1038/s41598-020-58902-x
Autor:
Dorsa Sadat Kiaei, Valérie Larouche, Jean-Claude Décarie, Uri Tabori, Cynthia Hawkin, Sarah Lippé, Benjamin Ellezam, Luis H Ospina, Yves Théoret, Léandra Desjardins, Marie-Élaine Métras, Serge Sultan, Édith Cantin, Marie-Ève Routhier, Chantal Mailloux, Marie-Claude Bertrand, Maxime Caru, Stéphanie Vairy, Geneviève Legault, Éric Bouffet, Vijay Ramaswamy, Hallie Coltin, Lucie Lafay-Cousin, Juliette Hukin, Craig Erker, Nada Jabado, Mathieu Dehaes, Sébastien Perreault
Publikováno v:
Neuro-Oncology. 24:i129-i129
BACKGROUND: Plexiform neurofibromas (PN) are found in up to 50% of patients with neurofibromatosis type 1 (NF1). Trametinib has been used widely to treat PN but limited data has been reported on its efficacy within a clinical trial. METHODS: This ong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a3ce9de27d59c5aca9976f0c4504948
https://doi.org/10.1093/neuonc/noac079.472
https://doi.org/10.1093/neuonc/noac079.472
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 32:2130-2138
Objectives Milrinone pulmonary administration is used currently for the treatment of pulmonary hypertension. Several methods are available: simple jet nebulization, vibrating mesh nebulization, intratracheal instillation, and intratracheal atomizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861c4827a7ba7d7bcc4127f4119e70fb
https://doi.org/10.1053/j.jvca.2018.01.031
https://doi.org/10.1053/j.jvca.2018.01.031
Autor:
Nicolas Poirier, Elie Haddad, Michel Duval, Valérie Paquin, Séverine Leclerc, Véronique Lisi, Carolina Marmolejo, Hicham Affia, Paulo Cordeiro, Yves Théorêt, Gregor Andelfinger, Vincent Philippe Lavallée, Sabine Herblot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Allogeneic hematopoietic stem cell transplantation (HSCT) remains the standard of care for chemotherapy-refractory leukemia patients, but cure rates are still dismal. To prevent leukemia relapse following HSCT, we aim to improve the early
Externí odkaz:
https://doaj.org/article/f0f0716f6dc24b4b8ba472b368e8d196
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 46:20-29
Cardiopulmonary bypass triggers an ischemia-reperfusion injury with endothelial dysfunction in the pulmonary circulation which can result in pulmonary hypertension. Inhaled milrinone reduces this reperfusion phenomenon and two methods commonly availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be489c131593d285c1e5d882ac07f9f9
https://doi.org/10.1016/j.pupt.2017.08.004
https://doi.org/10.1016/j.pupt.2017.08.004
Autor:
Yves Théorêt
Gérer son projet vise à adapter la gestion de projet aux besoins des chercheurs, des étudiants et des professionnels qui travaillent dans le domaine des sciences humaines. Il offre une vision d'ensemble des méthodes, des outils, des techniques et
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 10 (2017)
Background: Thiopurines, azathioprine (AZA) and 6-mercaptopurine (6-MP) are common maintenance medications for inflammatory bowel disease (IBD). Excessive methylation via thiopurine methyltransferase (TPMT) frequently causes therapeutic failure. Allo
Externí odkaz:
https://doaj.org/article/f1b55654b1974cc5836b0394982810de