Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yves Somers"'
Autor:
Henk van der Linde, Yves Somers, Bruce P. Damiano, Bruno Van Deuren, David J. Gallacher, Mariusz Lubomirski, Ard Teisman
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 72:72-84
Introduction Preclinical proarrhythmic risk assessment of drug candidates is focused predominantly on arrhythmias arising from repolarization abnormalities. However, drug-induced cardiac conduction slowing is associated with significant risk of life-
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:374
Publikováno v:
Current Protocols in Pharmacology
This unit describes a procedure for performing safety studies in the anesthetized beagle dog. Detailed are the anesthetic regime, the surgical procedure, and all materials needed to perform cardiovascular, central nervous system, and respiratory safe
Publikováno v:
Journal of the American College of Cardiology. 21:1269-1279
Objectives. We sought to examine to what extent a combination of strong thromboxane A2, synthase inhibition and moderate endoperoxide receptor blockade enhances streptokinase-induced coronary thrombolysis and provides anti-ischemic activity independe
Autor:
W.H. Drinkenburg, H.J. van der Linde, B. Van Deuren, Yves Somers, Ard Teisman, David J. Gallacher
Publikováno v:
Journal of pharmacological and toxicological methods. 63(1)
Introduction The purpose of this study was to explore the integration of electroencephalographical (EEG) measurements into the fentanyl/etomidate-anaesthetised Beagle (FEAB) model in order to detect burst suppression and/or seizure development caused
Publikováno v:
British Journal of Pharmacology. 99:631-636
1. The pathways contributing to the platelet adhesion/aggregation reaction elicited by collagen microfibrils, administered to cats in vivo, were analysed. 2. The intra-aortic infusion of collagen (100 micrograms kg-1 in 1 min) caused an extensive act
Autor:
Henk van der Linde, Bruce Damiano, Bruno Van Beuren, Ard Teisman, Yves Somers, David J. Gallacher
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 70:341
Autor:
Bruno Van Deuren, Ard Teisman, Hua Rong Lu, Yves Somers, David J. Gallacher, Brigitte Loenders, Henk van der Linde
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 70:346
Autor:
Yves Somers, Jan D'Aubioul, David J. Gallacher, Brigitte Loenders, Sigrid Janssens, Ard Teisman, Jan Verrelst
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 58:147-148
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 64:e4